Abstract:
:Using a material that already is in widespread use in humans, India ink, the first EPR measurements in a human have been made, using the India ink in a pre-existing tattoo. The EPR spectra of India ink are very sensitive to the partial pressure of oxygen (pO2), thereby making it feasible to use this approach to measure pO2 in tissues in patients. This potentially provides a means to measure this parameter directly with a sensitivity, accuracy, and repeatability that have not been available previously, and thereby to be able to individualize and guide treatment of diseases such as cancer and peripheral vascular insufficiency.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Swartz HM,Liu KJ,Goda F,Walczak Tdoi
10.1002/mrm.1910310218subject
Has Abstractpub_date
1994-02-01 00:00:00pages
229-32issue
2eissn
0740-3194issn
1522-2594journal_volume
31pub_type
杂志文章abstract::The feasibility of MR subtraction imaging of lung ventilation using air against oxygen using a multiple inversion recovery half-Fourier single-shot turbo spin echo (MIR-HASTE) sequence was investigated. Eight healthy, nonsmoking volunteers (3 males, 5 females; from 27 to 48 years of age) were studied on a 1.5 T MR uni...
journal_title:Magnetic resonance in medicine
pub_type: 临床试验,杂志文章
doi:10.1002/1522-2594(200006)43:6<913::aid-mrm21>3.0.c
更新日期:2000-06-01 00:00:00
abstract::The study of lung perfusion in normal and diseased subjects is of great interest to physiologists and physicians. In this work we demonstrate the application of a liquid-phase hyperpolarized (HP) carbon-13 ((13)C) tracer to magnetic resonance imaging (MRI) of the pulmonary vasculature and pulmonary perfusion in a porc...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21168
更新日期:2007-03-01 00:00:00
abstract::A new contrast preparation based on modified driven equilibrium Fourier transfer is introduced and evaluated for generation of T1-weighted images for assessment of the myocardial perfusion with contrast agent first-pass kinetics. The new preparation scheme produces T1 contrast with insensitivity to arrhythmias in pros...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910340408
更新日期:1995-10-01 00:00:00
abstract::Manganese-enhanced MRI has previously been used for visualization of brain architecture and functional mapping of neural pathways. The present work investigated the potential of manganese-enhanced MRI for noninvasive imaging of salivary glands in living subjects. Marked shortening of T(1) was observed in salivary glan...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22452
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:A purely experimental method for MRI-based transfer function (TF) determination is presented. A TF characterizes the potential for radiofrequency heating of a linear implant by relating the incident tangential electric field to a scattered electric field at its tip. We utilize the previously introduced transfer...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27974
更新日期:2020-03-01 00:00:00
abstract::Lower extremity peripheral vein bypass grafts (LE-PVBG) imaged with high-resolution black blood three-dimensional (3D) inner-volume (IV) fast spin echo (FSE) MRI at 1.5 Tesla possess a two-layer appearance in T1W images while only the inner layer appears visible in the corresponding T2W images. This study quantifies t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22037
更新日期:2009-09-01 00:00:00
abstract::The rotating ultra-fast imaging sequence (RUFIS) is used to image spins flowing through the curved portion of a 180 degrees U-tube with a circular cross section and a ratio of inner diameter to curvature diameter of 0.41. A velocity-encoding preparation sequence is used with RUFIS to measure quantitatively the axial v...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(199906)41:6<1258::aid-mrm2
更新日期:1999-06-01 00:00:00
abstract::The hypothesis was tested that the intravoxel distribution of water diffusion rates, as measured with a stretched-exponential model of diffusion-weighted imaging (DWI), is a marker of brain tumor invasion. Eight rats underwent intracerebral inoculation of C6 glioma cells. In three rats, cells were labeled with a fluor...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20286
更新日期:2004-11-01 00:00:00
abstract::Some of the factors involved in the choice of field strength for NMR imaging are examined. The influences of relaxation times and chemical shift upon image quality and signal-to-noise ratio are highlighted, and power deposition is introduced as a significant factor which may limit the flexibility and information avail...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910030509
更新日期:1986-10-01 00:00:00
abstract:PURPOSE:Vulnerable atherosclerotic plaques are structurally weak and prone to rupture, presumably due to local oxidative stress. Redox active iron is linked to oxidative stress and the aim of this study was to investigate the distribution of Fe(III) in carotid plaques and its relation to vulnerability for rupture. MET...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24687
更新日期:2014-02-01 00:00:00
abstract::A common type of motion present in clinical magnetic resonance imaging examinations is rotational motion, such as that due to voluntary motion during head examinations. The correction scheme presented in this work offers a method for eliminating the effects of rotations within the imaging plane. Integral to the implem...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910330511
更新日期:1995-05-01 00:00:00
abstract::A new fully automatic algorithm for the segmentation of the brain and total intracranial cerebrospinal fluid (CSF) from T(1)-weighted volume MRI scans of the head, called Exbrain v.2, is described. The algorithm was developed in the context of serial intracranial volumetry. A brain mask obtained using a previous versi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10436
更新日期:2003-05-01 00:00:00
abstract::The relaxivities (R-values) of the gadolinium diethylene triamine pentaacetic acid (Gd(DTPA)2-) ions in a series of skim-milk solutions at 0-40% milk concentrations were measured using NMR spectroscopy. The R-value was found to be approximately linearly proportional to the concentration of the solid component in the m...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22169
更新日期:2010-01-01 00:00:00
abstract::A fast, two-coil, pseudo-continuous labeling scheme is presented. This new scheme permits the collection of a multislice subtraction pair in <3 s, depending on the subject's arterial transit times. The method consists of acquiring both control and tag images immediately after a labeling period that matches the arteria...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10733
更新日期:2004-03-01 00:00:00
abstract::Proton MR spectroscopy ((1)H-MRS) has been used for in vivo quantification of intracellular triglycerides within the sarcolemma. The purpose of this study was to assess whether breath-hold dual-echo in- and out-of-phase MRI at 3.0 T can quantify the fat content of the myocardium. Biases, including T(1), T*(2), and noi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22289
更新日期:2010-04-01 00:00:00
abstract::In the dynamic nuclear polarization process, microwave irradiation facilitates exchange of polarization from a radical's unpaired electron to nuclear spins at cryogenic temperatures, increasing polarization by >10,000. Doping samples with Gd(3+) ions further increases the achievable solid-state polarization. However, ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24207
更新日期:2012-12-01 00:00:00
abstract::A planar YBa2Cu3Ox (YBCO) coil has been used as a pick-up coil in a nuclear magnetic resonance imager. It was found that the quality factor (Q) of the YBCO coil was greater than its copper counterpart by approaching 50% even in a field of 0.15 T. The Q of the copper coil at 77 K and in a field of 0.15 T was 1200 while...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910200218
更新日期:1991-08-01 00:00:00
abstract:PURPOSE:Diabetic nephropathy (DN) is the leading cause of renal failure; however, current clinical tests are insufficient for assessing this disease. DN is associated with changes in renal metabolites, so we evaluated the utility of chemical exchange saturation transfer (CEST) imaging to detect changes characteristic o...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26045
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:High-resolution three-dimensional (3D) structural MRI is useful for delineating complex or small structures of the body. However, it requires long acquisition times and high SAR, limiting its clinical use. The purpose of this work is to accelerate the acquisition of high-resolution images by combining compresse...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27789
更新日期:2019-09-01 00:00:00
abstract::This review reports data on the general and renal tolerance of the paramagnetic contrast agent Gd-DTPA after intravenous administration. Gd-DTPA was administered usually at a dose level of 0.1-0.2 mmol/kg body wt (range: 0.005-0.25 mmol/kg body wt) in cranial, spinal and body MR indications. In phase I-IIIa studies a ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章,评审
doi:10.1002/mrm.1910220212
更新日期:1991-12-01 00:00:00
abstract:PURPOSE:High angular resolution diffusion imaging (HARDI) is a well-established method to help reveal the architecture of nerve bundles, but long scan times and geometric distortions inherent to echo planar imaging (EPI) have limited its integration into clinical protocols. METHODS:A fast imaging method is proposed he...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26163
更新日期:2017-02-01 00:00:00
abstract::The magnetization subtraction technique (MS), which is equivalent to the inversion recovery technique in strong magnetic fields, has been implemented in dynamic nuclear polarization-enhanced magnetic resonance imaging (DNPI). The general theoretical basis of the MS method, which can be applied to DNPI or to prepolariz...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910350316
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:To develop a fast protocol for measuring T1 values in the internal carotid artery (ICA), to validate this technique with in vitro measurements, and to evaluate its reproducibility. METHODS:A modified Look-Locker sequence was optimized to enable rapid determination of T1 in the ICA at 3T. T1 values from the ICA...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26325
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:To optimize 3D radial ultrashort echo time MRI for high resolution whole-lung imaging. METHODS:3D radial ultrashort echo time was implemented on a 3T scanner to investigate the effects of: (1) limited field-of-view excitation, (2) variable density readouts, and (3) radial oversampling. Improvements in noise pe...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24570
更新日期:2013-11-01 00:00:00
abstract::A stimulated echo sequence was used to obtain 19F NMR spectra from within a 4-ml voxel in a cat brain. The time dependence of the 19F NMR signal from an inert gas (CHF3) was used to calculate the blood flow in the voxel. The position of the voxel was selected using a 1H MR image. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910160316
更新日期:1990-12-01 00:00:00
abstract::We have noninvasively produced low-resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2-ml voxels in eight cats. Typical signal-to-noise of 4 to 1 was obtained in cerebral voxels in 16.5-s epochs. Mean flow during normocapnia (paCO2 = 39 +/- 4 mm Hg) and hypercapnia (paCO2 = 62 +/- 4 ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910280105
更新日期:1992-11-01 00:00:00
abstract::The sensitivity of diffusion-weighted MRI was compared to that of T2-weighted MRI following temporary middle cerebral artery occlusion (MCA-O) for 33 min followed by 4 h of reperfusion in rats. Diffusion-weighted spin-echo images using strong gradients (b value of 1413 s/mm2) demonstrated a significant increase in sig...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910180106
更新日期:1991-03-01 00:00:00
abstract::Patient-specific radiofrequency shimming in high-field MRI strengthens the need for online, patient-specific specific absorption rate (SAR) monitoring. Numerical simulation is currently most effective for this purpose but may require a patient-specific dielectric model. To investigate whether a generic model may be co...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24378
更新日期:2013-05-01 00:00:00
abstract::Cervical spinal cord spectroscopy has the potential to add metabolic information to spinal cord MRI and improve the clinical evaluation and research investigation of spinal cord diseases, such as multiple sclerosis (MS) and intraspinal tumors. However, in vivo proton MR spectroscopy ((1)H-MRS) of the spinal cord is di...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21113
更新日期:2007-01-01 00:00:00
abstract::Partial-volume effects (PVE) in stroke imaging could hinder proper delineation of normal, ischemic, and at-risk tissues. Cerebral-blood-flow (CBF) and apparent diffusion coefficient (ADC) were measured at high and low resolution (HR = 128 x 128, LR = 64 x 64) in focal ischemia in rats during the acute phase. The data ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20299
更新日期:2004-12-01 00:00:00