Abstract:
:The study of lung perfusion in normal and diseased subjects is of great interest to physiologists and physicians. In this work we demonstrate the application of a liquid-phase hyperpolarized (HP) carbon-13 ((13)C) tracer to magnetic resonance imaging (MRI) of the pulmonary vasculature and pulmonary perfusion in a porcine model. Our results show that high spatial and temporal resolution images of pulmonary perfusion can be obtained with this contrast technique. Traditionally, pulmonary perfusion measurement techniques have been challenging because of insufficient signal for quantitative functional assessments. The use of polarized (13)C in MRI overcomes this limitation and may lead to a viable clinical method for studying the pulmonary vasculature and perfusion.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Ishii M,Emami K,Kadlecek S,Petersson JS,Golman K,Vahdat V,Yu J,Cadman RV,MacDuffie-Woodburn J,Stephen M,Lipson DA,Rizi RRdoi
10.1002/mrm.21168subject
Has Abstractpub_date
2007-03-01 00:00:00pages
459-63issue
3eissn
0740-3194issn
1522-2594journal_volume
57pub_type
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