Abstract：
:Meiotic fine-structure maps of two efficient UGA suppressors of Schizosaccharomyces pombe which are known (sup8-e) or inferred (sup10-e) to code for two leucine tRNAs carrying the mutant anticodon U(*)CA (Kohli et al. 1979, 1980a, b; Wetzel et al. 1979; Mao et al. 1981) are presented. In both cases, the recombination frequencies given by the primary site of the anticodon mutation fitwell into the map defined by the sites of a number of inactivating secondary mutations. This contrasts the corresponding situation found in the serine tRNA genes sup3 and sup9 where the anticodon site exhibits a specific marker effect which strongly increases recombination frequencies in crosses with all revertant sites, due to a decrease in the efficiency of excision repair of base-pair mismatches whenever the anticodon site is included in hybrid-DNA (Hofer et al. 1979; Munz and Leupold 1979; Thuriaux et al. 1980). A pronounced specific marker effect which leads to a several fold increase of the recombination frequencies over those expected is observed, however, at one of the secondary inactivating sites mapping in the leucine tRNA gene sup8.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Munz P,Dorsch-Häsler K,Leupold Udoi
10.1007/BF00365633subject
Has Abstractpub_date
1983-04-01 00:00:00pages
101-8issue
2eissn
0172-8083issn
1432-0983journal_volume
7pub_type
杂志文章相关文献
CURRENT GENETICS文献大全abstract：:Cyh3 and cyh4, multiple drug resistant strains of Schizosaccharomyces pombe, show a much reduced uptake of trichodermin, chloramphenicol, cycloheximide, L-lysine, glycine, L-threonine, L-glutamine, L-arginine and L-glutamic acid when compared to wild type. The plasma membrane and mitochondrial ATPase activities of the...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00376075
更新日期：1983-07-01 00:00:00
abstract：:Sister chromatid cohesion is essential for chromosome segregation both in mitosis and meiosis. Cohesion between two chromatids is mediated by a protein complex called cohesin. The loading and unloading of the cohesin are tightly regulated during the cell cycle. In vertebrate cells, cohesin is released from chromosomes...
journal_title：Current genetics
pub_type： 杂志文章,评审
doi：10.1007/s00294-019-00959-x
更新日期：2019-08-01 00:00:00
abstract：:Cohesin is essential for sister chromatid cohesion, which ensures equal segregation of the chromatids to daughter cells. However, the molecular mechanism by which cohesin mediates this function is elusive. Scc3, one of the four core subunits of cohesin, is vital to cohesin activity. However, the mechanism by which Scc...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-020-01150-3
更新日期：2021-01-06 00:00:00
abstract：:The het-c locus controls heterokaryon formation in Neurospora crassa. It is subject to balancing selection operating to maintain polymorphism at that locus in natural populations. We have isolated hch, the het-c homolog from the related species Podospora anserina (hch for het-c homolog), in order to determine if this ...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s002940000130
更新日期：2000-07-01 00:00:00
abstract：:A DNA fragment which carries the leu1 gene encoding beta-isopropylmalate dehydrogenase in Schizosaccharomyces pombe has been isolated by complementation of an E. coli leuB mutation. This 1.5 kb DNA fragment complements not only the S. pombe leu1 mutation, but also the S. cerevisiae leu2 mutation. The nucleotide sequen...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00419995
更新日期：1988-10-01 00:00:00
abstract：:In Chlamydomonas reinhardtii, the expression of the nit1 gene encoding nitrate reductase is dependent on the nature of the nitrogen source and on other environmental factors. We have fused the nit1 promoter region to the arylsulphatase (ars) reporter gene lacking its own promoter and introduced this chimeric construct...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s002940050204
更新日期：1997-03-01 00:00:00
abstract：:By using the fluorochrome 4'-6-diamidino-2-phenylindole (DAPI) to stain DNA one can follow the pattern of events affecting plastid DNA which occur in the formation and maturation of individual zygotes of the green flagellate Chlamydomonas moewusii. This species, like C. reinhardi, expresses uniparental inheritance of ...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00434892
更新日期：1983-06-01 00:00:00
abstract：:Genetic analysis of carotenogenesis in Phycomyces is hampered by the inability of most mutants to complete the sexual cycle. Heterokaryons between complementing mutants or between a mutant and a helper strain are, however, fertile. Using this method crosses have been carried out between mutants representing the differ...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00445733
更新日期：1982-05-01 00:00:00
abstract：:The mitochondrial leucyl-tRNA synthetase (mLRS) of Saccharomyces cerevisiae is involved in both mitochondrial protein synthesis and pre-mRNA splicing. We have created mutations in the regions HIGH, GWD and KMSKS, which are involved in ATP-, amino acid- and tRNA-binding respectively, and which have been conserved in th...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00351744
更新日期：1992-07-01 00:00:00
abstract：:The soil-borne, asexual fungus Fusarium oxysporum f.sp. lycopersici (Fol) is a causal agent of tomato wilt disease. The infection process of Fol comprises root recognition, adhesion, penetration, colonization of the root cortex and hyphal proliferation within the xylem vessels, which are under the regulation of virule...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-019-00931-9
更新日期：2019-06-01 00:00:00
abstract：:Degenerative processes in the filamentous fungus Podospora anserina are strongly correlated with the instability of the mitochondrial genome. Among the sources of instability is the mobile group-II intron COX1-i1, also called intron alpha, which encodes a protein with a reverse transcriptase activity. In this paper we...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s002940050003
更新日期：2000-01-01 00:00:00
abstract：:Phylum Euglenozoa comprises three groups of eukaryotic microbes (kinetoplastids, diplonemids, and euglenids), the mitochondrial (mt) genomes of which exhibit radically different modes of organization and expression. Gene fragmentation is a striking feature of both euglenid and diplonemid mtDNAs. To rationalize the eme...
journal_title：Current genetics
pub_type： 杂志文章,评审
doi：10.1007/s00294-011-0340-8
更新日期：2011-08-01 00:00:00
abstract：:A main function of ectomycorrhizas, a symbiosis between certain soil fungi and fine roots of woody plants, is the exchange of plant-derived carbohydrates for fungus-derived nutrients. As it is required in large amounts, nitrogen is of special interest. A gene (AmAMT2) coding for a putative fungal ammonium importer was...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-006-0106-x
更新日期：2007-02-01 00:00:00
abstract：:The Cys6Zn2 DNA-binding domain transcription factor Pdr1 is a central regulator of drug resistance in the pathogenic yeast Candida glabrata. In this review, I discuss the multiple control mechanisms modulating the function of this positive transcriptional regulator. Available data suggest that Pdr1 activity is restrai...
journal_title：Current genetics
pub_type： 杂志文章,评审
doi：10.1007/s00294-018-0870-4
更新日期：2019-02-01 00:00:00
abstract：:The Saccharomyces cerevisiae open reading frame YDL202w has been characterised in the course of the EUROFAN yeast genome analysis program. Disruption of YDL202w causes a respiratory deficient phenotype accompanied by a loss of mitochondrial DNA. This phenotype is usually found in mutants defective in mitochondrial rep...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s002940050221
更新日期：1997-05-01 00:00:00
abstract：:An electrophoretic karyotype of the filamentous fungus Podospora anserina has been obtained using contour-clamped homogeneous electric field gel electrophoresis. Six chromosomal bands were separated with one migrating as a doublet. The size of the chromosomes was estimated to be between 3.8 and 6.0 megabase pairs (mb)...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00351795
更新日期：1993-09-01 00:00:00
abstract：:Genetic analysis of the MAL6 locus has previously yielded mal6 mutants which fall into a single complementation group and which are noninducible for maltase and maltose permease. However, the strains used in these studies contained additional partially functional copies of MAL1 (referred to as MAL1g) and MAL3 (referre...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00376740
更新日期：1988-09-01 00:00:00
abstract：:DNA replication checkpoint is a cell signaling pathway that is activated in response to perturbed replication. Although it is crucial for maintaining genomic integrity and cell survival, the exact mechanism of the checkpoint signaling remains to be understood. Emerging evidence has shown that RecQ helicases, a large f...
journal_title：Current genetics
pub_type： 杂志文章,评审
doi：10.1007/s00294-020-01147-y
更新日期：2021-01-11 00:00:00
abstract：:The wheat mitochondrial (mt) cox3 has been localized and sequenced. The gene exists as a single copy in the wheat mt master chromosome and is transcribed into a single 1.2 kb RNA, whose extremities have been mapped. Comparison of the wheat and Oenothera cox3 sequences gives ambiguous indications concerning the amino a...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00313247
更新日期：1990-01-01 00:00:00
abstract：:Mutants resistant to 200 micrograms/ml of the alkaloid lycorine (LYCR) in non-fermentable substrate were isolated after nitrosoguanidine mutagenesis. Tetrad analysis and growth of heterozygous (LYCR/lycS) diploids from two different mutants revealed that a single nuclear and dominant mutation is responsible for the re...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00420614
更新日期：1986-01-01 00:00:00
abstract：:In the wood destroying fungus Schizophyllum commune, a well known subject for genetic studies, fruit bodies are produced not only in the course of the sexual cycle but also asexually. Sexual fruiting requires the establishment of a dikaryon which is under the control of the incompatibility factors A and B. Asexual fru...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00413309
更新日期：1979-12-01 00:00:00
abstract：:The A-pathway of development in the basidiomycete fungus Schizophyllum commune may be activated by either of two mating-type loci, A alpha and A beta. A alpha consists of two multiallelic genes, Y and Z. Y contains a putative homeodomain; Z contains a homeodomain-related region. Non-self combinations of Y and Z form h...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF02221577
更新日期：1996-01-01 00:00:00
abstract：:A screening procedure for cell cycle mutants among is mutants of Physarum has been developed for unsynchronized microplasmodia. The synchronization of the microplasmodia and the ratio of pre- to post-mitotic nuclei were evaluated after a transient shift-up to the non-permissive temperature. In contrast with wild type ...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00390945
更新日期：1980-04-01 00:00:00
abstract：:The cif1 mutation of Saccharomyces cerevisiae causes inability to grow on glucose and related fermentable carbon sources. We have isolated two different suppressor mutations that allow growth on glucose of yeasts carrying the cif1 mutation. One of them, sci1-1, is recessive and caused inability to grow on non-fermenta...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00309531
更新日期：1994-02-01 00:00:00
abstract：:Expression of pho1-encoded acid phosphatase of Schizosaccharomyces pombe has been reported to be regulated by phosphate. In this communication we show that it is also regulated by adenine. Starving adenine auxotrophic strains for adenine leads to a drastic increase of the enzymatic activity while adenine represses thi...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/BF00317923
更新日期：1992-10-01 00:00:00
abstract：:The RAD52 group of genes in the yeast Saccharomyces cerevisiae controls the repair of DNA damage by a recombinational mechanism. Despite the growing evidence for physical and biochemical interactions between the proteins of this repair group, mutations in individual genes show very different effects on various types o...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s002940050467
更新日期：1999-08-01 00:00:00
abstract：:The cloning of fga1, the gene encoding a G protein alpha subunit, was performed by standard PCR techniques and by screening a Fusarium oxysporum genomic library, using the PCR product as a probe. The full-length open reading frame spanned 1,059 nucleotides and the deduced primary structure of the protein (353 amino ac...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-002-0322-y
更新日期：2002-09-01 00:00:00
abstract：:Glycerophosphoinositol (GroPIns) and glycerophosphocholine (GroPCho) are the products of phospholipase-B mediated deacylation of phosphatidylinositol and phosphatidylcholine, respectively. GroPIns and GroPCho are transported across the Saccharomyces cerevisiae plasma membrane into the cell via the transporter encoded ...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-006-0096-8
更新日期：2006-12-01 00:00:00
abstract：:Approximately, 1% of the genes in eukaryotic genomes encode for helicases, which make the number of helicases expressed in the cell considerably high. Helicases are motor proteins that participate in many central aspects of the nuclear and mitochondrial genomes, and based on their helicase motif conservation, they are...
journal_title：Current genetics
pub_type： 杂志文章,评审
doi：10.1007/s00294-016-0675-2
更新日期：2017-08-01 00:00:00
abstract：:The mother-bud neck is defined as the boundary between the mother cell and bud in budding microorganisms, wherein sequential morphological events occur throughout the cell cycle. This study was designed to quantitatively investigate the morphology of the mother-bud neck in budding yeast Saccharomyces cerevisiae. Obser...
journal_title：Current genetics
pub_type： 杂志文章
doi：10.1007/s00294-018-0872-2
更新日期：2019-02-01 00:00:00
