Potential roles of ATP and local neurons in the monitoring of blood O2 content by rat aortic bodies.

abstract：NEW FINDINGS:What is the central question of this study? What is the nature of slow wave-driven contraction frequency gradients in the small intestine? What is the main finding and its importance? Frequency plateaux are composed of discrete waves of increased interval, each wave associated with a contraction dislocatio...

journal_title：Experimental physiology

authors： Parsons SP,Huizinga JD

更新日期：2018-08-01 00:00:00

abstract：:The effect of the neuronal 5-HT3 receptor antagonist MDL 72222 has been investigated on the reflex tachypnoeic response to pulmonary embolism in pentobarbitone-anaesthetized rabbits. Pre-treatment with MDL 72222 (640 micrograms kg-1, 5 min prior to embolization) significantly attenuated the reflex tachypnoeic response...

journal_title：Experimental physiology

authors： Armstrong DJ,Kay IS

更新日期：1990-07-01 00:00:00

abstract：:The role of bicarbonate as a hydrogen ion buffer has been investigated using the fluorescent dye BCECF in individual rat cerebellar, hippocampal and neocortical neurones maintained in culture. The steady-state intracellular pH (pHi) was estimated to be 7.07 +/- 0.05 (n = 22) in CO2-HCO3(-)-buffered media. Buffering po...

journal_title：Experimental physiology

authors： Amos BJ,Pocock G,Richards CD

更新日期：1996-07-01 00:00:00

abstract：:It has been shown previously that the amplitudes of the harmonic components of the pulse spectrum vary in specific patterns when the arteries leading to different organs are ligated, with the variations in the harmonics being linearly additive. Since ligation can be regarded as a vast increase in organ resistance, the...

journal_title：Experimental physiology

authors： Hsu TL,Chao PT,Hsiu H,Wang WK,Li SP,Wang YY

更新日期：2006-01-01 00:00:00

abstract：:Recent studies showed that progesterone stimulates the hypoxic ventilatory response and may reduce apnoea frequency in newborn rats, but so far we still do not know by what mechanisms and whether endogenous progesterone might contribute to respiratory control in neonates. We therefore determined the role of the nuclea...

journal_title：Experimental physiology

authors： Potvin C,Rossignol O,Uppari N,Dallongeville A,Bairam A,Joseph V

更新日期：2014-11-01 00:00:00

abstract：:The purpose of the present study was to characterize the Ca2+ channels in smooth muscle cells from human stomach and to examine the effects of osmotic swelling on the channel activity. Ca2+ channel current with either Ca2+ or Ba2+ as charge carrier was recorded from freshly isolated smooth muscle cells using the conve...

journal_title：Experimental physiology

authors： Kim CH,Rhee PL,Rhee JC,Kim YI,So I,Kim KW,Park MK,Uhm DY,Kang TM

更新日期：2000-09-01 00:00:00

abstract：:The present study examined whether an increase in leg blood flow and oxygen delivery at the onset of intense exercise would speed the rate of rise in leg oxygen uptake. Nine healthy men (25 ± 1 years old, mean ± SEM) performed one-leg knee-extensor exercise (62 ± 3 W, 86 ± 3% of incremental test peak power) for 4 min ...

journal_title：Experimental physiology

authors： Nyberg M,Christensen PM,Mortensen SP,Hellsten Y,Bangsbo J

更新日期：2014-10-01 00:00:00

abstract：:In humans, skeletal muscle blood flow is regulated by an interaction between several locally formed vasodilators, including NO and prostaglandins. In plasma, ATP is a potent vasodilator that stimulates the formation of NO and prostaglandins and, very importantly, can offset local sympathetic vasoconstriction. Adenosin...

journal_title：Experimental physiology

authors： Mortensen SP,Saltin B

更新日期：2014-12-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What is the precise subcellular localization of the epithelial sodium channel (ENaC) in human airway epithelium? What is the main finding and its importance? ENaC protein has an unexpected localization in the peripheral region of the apical membrane of bronchial ...

journal_title：Experimental physiology

authors： Musante I,Scudieri P,Venturini A,Guidone D,Caci E,Castellani S,Conese M,Galietta LJV

更新日期：2019-06-01 00:00:00

abstract：:The renin-angiotensin system is activated in the early phase of two-kidney, one-clip (2K-1C) hypertension. The paraventricular nucleus (PVN) integrates inputs regulating sympathetic outflow. The PVN receives inputs from plasma angiotensin II via projections from circumventricular organs and from renal afferent nerves ...

journal_title：Experimental physiology

authors： Rossi NF,Maliszewska-Scislo M,Chen H,Black SM,Sharma S,Ravikov R,Augustyniak RA

更新日期：2010-08-01 00:00:00

abstract：:Pairs of Ia and II afferent fibres supplying primary and secondary endings lying in the same tenuissimus spindles were prepared in barbiturate anaesthetized cats in order to compare the variability in the rhythm of discharge of the two endings during responses elicited by the contraction of different intrafusal muscle...

journal_title：Experimental physiology

authors： Celichowski J,Emonet-Dénand F,Gladden M,Laporte Y,Petit J

更新日期：1994-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the characteristics of the NK cell response following acute moderate-intensity aerobic exercise in prostate cancer survivors and is there a relationship between stress hormones and NK cell mobilization? What is the main finding and its importance? NK cel...

journal_title：Experimental physiology

authors： Hanson ED,Sakkal S,Que S,Cho E,Spielmann G,Kadife E,Violet JA,Battaglini CL,Stoner L,Bartlett DB,McConell GK,Hayes A

更新日期：2020-09-01 00:00:00

abstract：:The purpose of the present study was to investigate the effect of temperature on the rates of isometric force development and relaxation in electrically activated fresh and fatigued human adductor pollicis muscle. Following immersion of the lower arm for 20 min in water baths of four different temperatures, muscle tem...

journal_title：Experimental physiology

authors： de Ruiter CJ,Jones DA,Sargeant AJ,de Haan A

更新日期：1999-11-01 00:00:00

abstract：:The effect of resistance training on arterial stiffening is controversial. We tested the hypothesis that resistance training would not alter central arterial compliance. Young healthy men (age, 23 +/- 3.9 (mean +/- s.e.m.) years; n = 28,) were whole-body resistance trained five times a week for 12 weeks, using a rotat...

journal_title：Experimental physiology

authors： Rakobowchuk M,McGowan CL,de Groot PC,Bruinsma D,Hartman JW,Phillips SM,MacDonald MJ

更新日期：2005-07-01 00:00:00

abstract：:A method is described that enables the cell membrane of isolated rat ventricular myocytes to be permeabilized and resealed while maintaining cell viability. Streptolysin O, a cholesterol-binding cytolysin, was used to form pores in the surface membrane; subsequent incubation with 5% fetal bovine serum was used to reve...

journal_title：Experimental physiology

authors： Fawcett JM,Harrison SM,Orchard CH

更新日期：1998-05-01 00:00:00

abstract：:After food is ingested, nutrients pass through the gastrointestinal tract, stimulating the release of a range of peptide hormones. Among their many local, central and peripheral actions, these hormones act to mediate glucose metabolism and satiety. Indeed, it is the modification of gut hormone secretion that is consid...

journal_title：Experimental physiology

authors： Parker HE,Gribble FM,Reimann F

更新日期：2014-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? The central question of this study was to investigate the interaction of mild exposures to O2 and CO2 on chemoreflex control of SNA and the modulation of lung volume and respiratory phase on this interaction. What is the main finding and its importance? We demons...

journal_title：Experimental physiology

authors： Jouett NP,Watenpaugh DE,Dunlap ME,Smith ML

更新日期：2015-09-01 00:00:00

abstract：:Progressive asphyxia, produced by a prolonged voluntary breath hold (end-expiratory apnoea), evokes large bursts of muscle sympathetic nerve activity (MSNA). These bursts increase in amplitude until the asphyxic break point is reached, at which point the bursts are inhibited. We tested the hypothesis that lung inflati...

journal_title：Experimental physiology

authors： Seitz MJ,Brown R,Macefield VG

更新日期：2013-02-01 00:00:00

abstract：:Duchenne muscular dystrophy is a devastating muscular dystrophy of childhood. Mutations in the dystrophin gene destroy the link between the internal muscle filaments and the extracellular matrix, resulting in severe muscle weakness and progressive muscle wasting. There is currently no cure and, whilst palliative treat...

journal_title：Experimental physiology

authors： Fairclough RJ,Bareja A,Davies KE

更新日期：2011-11-01 00:00:00

abstract：:It is debatable whether differences in mitochondrial function exist across skeletal muscle types and whether mouse skeletal muscle mitochondrial function can serve as a valid model for human skeletal muscle mitochondrial function. The aims of this study were to compare and contrast three different mouse skeletal muscl...

journal_title：Experimental physiology

authors： Jacobs RA,Díaz V,Meinild AK,Gassmann M,Lundby C

更新日期：2013-04-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Should we use the high-frequency (HF) component of P-P interval as an index of cardiac parasympathetic nerve activity during moderate exercise? What is the main finding and its importance? The HF component of P-P interval variability remained even at a heart rate...

journal_title：Experimental physiology

authors： Takahashi M,Nakamoto T,Matsukawa K,Ishii K,Watanabe T,Sekikawa K,Hamada H

更新日期：2016-03-01 00:00:00

abstract：:This study examined whether left ventricular function was reduced during 3 h of semi-recumbent ergometer cycling at 70% of maximal oxygen uptake while preload to the heart was maintained via saline infusion. Indices of left ventricular systolic function (end-systolic blood pressure-volume relationship, SBP/ESV) and di...

journal_title：Experimental physiology

authors： Dawson EA,Shave R,Whyte G,Ball D,Selmer C,Jans Ø,Secher NH,George KP

更新日期：2007-03-01 00:00:00

abstract：:There is controversy about the effect of left ventricular pressure on resistance of the intramyocardial coronary vessels. In anaesthetized dogs the effect of left ventricular pressure on coronary flow during diastole was studied using an extracorporeal circulation and allowing the heart to contract and relax isovolumi...

journal_title：Experimental physiology

authors： Gattullo D,Linden RJ,Losano G,Pagliaro P,Westerhof N

更新日期：1992-03-01 00:00:00

abstract：:The endothelial glycocalyx layer of capillaries was stained with Ruthenium Red and examined by transmission electron microscopy in rat extensor hallucis proprius muscles after 2 or 4 days of indirect electrical stimulation via implanted electrodes. The layer appeared continuous on the luminal surface of 63% capillarie...

journal_title：Experimental physiology

authors： Brown MD,Egginton S,Hudlicka O,Zhou AL

更新日期：1996-11-01 00:00:00

abstract：:In this review we discuss our current understanding of the cellular basis of uterine contractility, highlighting those areas requiring further study. It is clear that the basic processes of excitation-contraction coupling lie within the myometrial cell, and that these may be modified by agonists. Pacemaker activity, h...

journal_title：Experimental physiology

authors： Wray S,Kupittayanant S,Shmygol A,Smith RD,Burdyga T

更新日期：2001-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the molecular underpinnings of seasonal metabolic plasticity during spring and autumn migrations in songbirds? What is the main finding and its importance? We report differences in mRNA levels of genes involved in the regulation of glucose and fat metabo...

journal_title：Experimental physiology

authors： Sharma A,Kumar V

更新日期：2019-12-01 00:00:00

abstract：:We hypothesized that exercise performance is adjusted during repeated sprints in order not to surpass a critical threshold of peripheral fatigue. Twelve men randomly performed three experimental sessions on different days, i.e. one single 10 s all-out sprint and two trials of 10 × 10 s all-out sprints with 30 s of pas...

journal_title：Experimental physiology

authors： Hureau TJ,Olivier N,Millet GY,Meste O,Blain GM

更新日期：2014-07-01 00:00:00

abstract：:Experiments were carried out to examine the perceived position of the human index finger about the proximal interphalangeal joint. In protocol I, the finger was moved from an intermediate position at velocities ranging from 200 deg/min to 2 deg/min, then held still at one of three positions. The subject's task was vis...

journal_title：Experimental physiology

authors： Ferrell WR,Craske B

更新日期：1992-03-01 00:00:00

abstract：:It is now well accepted that the sympathetic nervous system responds to specific afferent stimuli in a unique non-uniform fashion. The means by which the brain transforms the signals from a single type of receptor into an appropriate differential sympathetic output is discussed in this brief review. The detection of a...

journal_title：Experimental physiology

authors： Coote JH

更新日期：2005-03-01 00:00:00

abstract：:An imaging technique (laser Doppler perfusion imaging, LDI), based on measurement of backscattered Doppler-broadened laser radiation, was used to provide two-dimensional images of perfusion in the exposed rat knee joint capsule. In control animals, frequency-dependent constriction of knee joint blood vessels occurred ...

journal_title：Experimental physiology

authors： Karimian SM,McDougall JJ,Ferrell WR

更新日期：1995-05-01 00:00:00