Organ-specific ligation-induced changes in harmonic components of the pulse spectrum and regional vasoconstrictor selectivity in Wistar rats.

abstract：:Exposure to whole-body vibration is implicated as one of the occupational risk factors for lower back disorders; however, its influence on the lumbar muscle physiology is still poorly understood. The objective of this study was to investigate the effects of backrest support and hand grip contractions on lumbar muscle ...

journal_title：Experimental physiology

authors： Maikala RV,Bhambhani YN

更新日期：2006-09-01 00:00:00

abstract：:A great deal of knowledge exists regarding neural control of myocardial function in the rat. Most of the studies addressing this issue were conducted either under general anaesthesia or in isolated hearts in vitro. Our principal aim was to provide a detailed quantitative description of mechanisms controlling cardiac c...

journal_title：Experimental physiology

authors： Nalivaiko E,Antunes VR,Paton JF

更新日期：2010-01-01 00:00:00

abstract：:Interdigestive intestinal motility, and especially phase III of the migrating myoelectric/motor complex (MMC), is responsible for intestinal clearance and plays an important role in prevention of bacterial overgrowth and translocation in the gut. Yet previous results from gnotobiotic rats have shown that intestinal mi...

journal_title：Experimental physiology

authors： Lesniewska V,Rowland I,Laerke HN,Grant G,Naughton PJ

更新日期：2006-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Although peripheral blood haematopoietic stem and progenitor cells are potentially important in regeneration after acute myocardial infarction, their self-renewal ability in the post-acute phase has not yet been addressed. What is the main finding and its importa...

journal_title：Experimental physiology

authors： Kröpfl JM,Spengler CM,Frobert A,Ajalbert G,Giraud MN

更新日期：2018-01-01 00:00:00

abstract：:Embryonic stem (ES) cells are pluripotent cells isolated from the inner cell mass of blastocysts. ES cells are able to differentiate into the three primitive layers (endoderm, mesoderm and ectoderm) of the organism, including the germline. To study early stages of development, as well as to investigate the impact of a...

journal_title：Experimental physiology

authors： Desbaillets I,Ziegler U,Groscurth P,Gassmann M

更新日期：2000-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does sex or neonatal stress affect the expression of pituitary adenylate cyclase-activating peptide or its receptors? What is the main finding and its importance? Neonatal-maternal separation stress has little long-lasting effect on the expression of pituitary ad...

journal_title：Experimental physiology

authors： Mosca EV,Rousseau JP,Gulemetova R,Kinkead R,Wilson RJ

更新日期：2015-02-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? The sympathetic control of renal sodium tubular reabsorption is dependent on activation of the intrarenal renin-angiotensin system and activation of the angiotensin II type 1 (AT1 ) receptor by angiotensin II. What advances does it highlight? Despite the fact that the inte...

journal_title：Experimental physiology

authors： Pontes RB,Girardi AC,Nishi EE,Campos RR,Bergamaschi CT

更新日期：2015-04-20 00:00:00

abstract：:For synaptic and cellular analyses of the mammalian respiratory network, intracellular recording and good pharmacological access to respiratory neurones is required. Using an existing arterially perfused in situ preparation of neonatal rat, we report on a method allowing stable intracellular recordings of ventrolatera...

journal_title：Experimental physiology

authors： Dutschmann M,Paton JF

更新日期：2003-11-01 00:00:00

abstract：:Non-invasive autonomic evaluation has used fast Fourier transform (FFT) to assign a range of low (LF) and high frequencies (HF) as markers of sympathetic and parasympathetic influences, respectively. However, FFT cannot be applied to brief transient phenomena, such as those observed on performing autonomic tests where...

journal_title：Experimental physiology

authors： Ducla-Soares JL,Santos-Bento M,Laranjo S,Andrade A,Ducla-Soares E,Boto JP,Silva-Carvalho L,Rocha I

更新日期：2007-07-01 00:00:00

abstract：:The glucagon response to insulin-induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham-operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 +/- 27 pg x ml(-1) at baseline versus 397 +/- 35 pg x ml(-1...

journal_title：Experimental physiology

authors： Kosa E,Maurel D,Siaud P

更新日期：2001-09-01 00:00:00

abstract：:The aim of the present work was to investigate the role of the serotoninergic system in the control of sodium appetite of hypothyroid rats (HTR) by administering drugs that affect the serotoninergic activity, and to compare the same homeostatic behaviour in euthyroid rats (ETR) also given these drugs. Fenfluramine (FE...

journal_title：Experimental physiology

authors： Badauê-Passos D Jr,Ventura RR,Silva LF,Olivares EL,Reis LC

更新日期：2003-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What mechanisms account for the hypotension observed during chronic elevations in circulating 5-hydroxytryptamine in rats? What is the main finding and its importance? Chronic 5-hydroxytryptamine-induced hypotension requires continued activation of the 5-HT7 rece...

journal_title：Experimental physiology

authors： Seitz BM,Fink GD,Watts SW

更新日期：2020-10-14 00:00:00

abstract：:Severe-intensity constant-work-rate exercise results in the attainment of maximal oxygen uptake, but the muscle metabolic milieu at the limit of tolerance (T(lim)) for such exercise remains to be elucidated. We hypothesized that T(lim) during severe-intensity exercise would be associated with the attainment of consist...

journal_title：Experimental physiology

authors： Vanhatalo A,Fulford J,DiMenna FJ,Jones AM

更新日期：2010-04-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? In fever, the most striking response in the acute phase reaction of systemic inflammation, plasma H2 S concentration increases. However, the role of endogenous peripheral H2 S in fever is unknown. What is the main finding and its importance? Endogenous peripheral...

journal_title：Experimental physiology

authors： Soriano RN,Braga SP,Breder JSC,Batalhao ME,Oliveira-Pelegrin GR,Ferreira LFR,Rocha MJA,Carnio EC,Branco LGS

更新日期：2018-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? At near-term gestation, foramen ovale blood flow accounts for a significant proportion of fetal left ventricular output. Can the foramen ovale increase its volume blood flow when right ventricular afterload is increased by main pulmonary artery occlusion? What is...

journal_title：Experimental physiology

authors： Lantto J,Erkinaro T,Haapsamo M,Huhta H,Voipio HM,Hohimer AR,Davis LE,Acharya G,Räsänen J

更新日期：2019-02-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Could different hormonally active substances, including oestrogen receptor (ER) agonists, protect against oxidative brain damage and memory impairment induced by a single epileptic seizure in rats? If so, which signalling mechanisms are involved in their anti-inf...

journal_title：Experimental physiology

authors： Koyuncuoğlu T,Arabacı Tamer S,Erzik C,Karagöz A,Akakın D,Yüksel M,Yeğen BÇ

更新日期：2019-12-01 00:00:00

abstract：:Neural mediation of the human cardiac response to isocapnic (IC) steady-state hypoxaemia was investigated using coarse-graining spectral analysis of heart rate variability (HRV). Six young adults were exposed in random order to a hypoxia or control protocol, in supine and sitting postures, while end-tidal PCO2 (PET,CO...

journal_title：Experimental physiology

authors： Lucy SD,Hughson RL,Kowalchuk JM,Paterson DH,Cunningham DA

更新日期：2000-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Nerve growth factor (NGF) is reportedly a mediator inducing urinary bladder dysfunction. Is NGF directly involved in hyperexcitability of capsaicin-sensitive C-fibre bladder afferent pathways after spinal cord injury (SCI)? What is the main finding and its import...

journal_title：Experimental physiology

authors： Shimizu T,Majima T,Suzuki T,Shimizu N,Wada N,Kadekawa K,Takai S,Takaoka E,Kwon J,Kanai AJ,de Groat WC,Tyagi P,Saito M,Yoshimura N

更新日期：2018-06-01 00:00:00

abstract：:Obstructive sleep apnoea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. Obstructive sleep apnoea has been associated with liver injury. Acetaminophen (APAP; known as paracetamol outside the USA) is one of the most commonly used drugs which has known hepatotoxicity. The goal of the present study was to...

journal_title：Experimental physiology

authors： Savransky V,Reinke C,Jun J,Bevans-Fonti S,Nanayakkara A,Li J,Myers AC,Torbenson MS,Polotsky VY

更新日期：2009-02-01 00:00:00

abstract：:Endothelium-dependent relaxation in response to histamine and ACh has been studied on precontracted aortic rings from control and salt-loaded Sprague-Dawley rats. Both ACh and histamine caused relaxation of the noradrenaline-induced precontraction only in the presence of the endothelium. The relaxation response to ACh...

journal_title：Experimental physiology

authors： Obiefuna PC,Sofola OA,Ebeigbe AB

更新日期：1991-01-01 00:00:00

abstract：:Recently, we reported the presence of a local renal aldosterone production. In the present study, we tested the hypothesis that local aldosterone production in the kidney contributes to renal inflammation, matrix formation and albuminuria associated with diabetes. We evaluated changes in renal aldosterone content (RAC...

journal_title：Experimental physiology

authors： Siragy HM,Xue C

更新日期：2008-07-01 00:00:00

abstract：:The spatiotemporal dynamics of intracellular calcium within the middle cerebral artery (MCA) isolated from stroke-prone spontaneously hypertensive rats (SHR-SP) were investigated using real-time confocal laser microscopy. At 3 months of age (prestroke), rhythmical changes in the [Ca(2+)](i) during the tonic phase were...

journal_title：Experimental physiology

authors： Hashimoto T,Kiya M,Ohata H,Miyazaki T,Shibata K,Nobe K,Honda K

更新日期：2012-02-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? The parasternal intercostal electromyogram (EMGpara) is known to provide an accurate, non-invasive index of respiratory load-capacity balance. Although relationships between EMGpara and both airflow obstruction and hyperinflation have been shown, the independent ...

journal_title：Experimental physiology

authors： MacBean V,Pringle CL,Lunt AC,Sharp KD,Ali A,Greenough A,Moxham J,Rafferty GF

更新日期：2017-04-01 00:00:00

abstract：:The vascular actions of insulin are complex, because it can stimulate both nitric oxide-mediated dilatation and endothelin (ET)-1-mediated constriction. We examined vasoreactivity to insulin in isolated feed arteries of the gastrocnemius (GFA) and soleus muscles (SFA) of 32-week-old Long-Evans Tokushima Otsuka (LETO) ...

journal_title：Experimental physiology

authors： Jenkins NT,Padilla J,Martin JS,Crissey JM,Thyfault JP,Rector RS,Laughlin MH

更新日期：2014-01-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review concerns the negative impact of pulmonary hypertension (PH) on the pulmonary haemodynamic and gas exchange responses to exercise, considering the mechanisms by which PH plays a role in exercise intolerance in heart failure (HF) patients. What advances does it h...

journal_title：Experimental physiology

authors： Taylor BJ,Shapiro BP,Johnson BD

更新日期：2020-02-24 00:00:00

abstract：:Recent studies showed that progesterone stimulates the hypoxic ventilatory response and may reduce apnoea frequency in newborn rats, but so far we still do not know by what mechanisms and whether endogenous progesterone might contribute to respiratory control in neonates. We therefore determined the role of the nuclea...

journal_title：Experimental physiology

authors： Potvin C,Rossignol O,Uppari N,Dallongeville A,Bairam A,Joseph V

更新日期：2014-11-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? One of the major unanswered questions in physiology is that of how breathing matches metabolic rate. Venous chemoreceptors seem to have been dismissed since the 1960s. What advances does it highlight? New evidence shows that their apparent dismissal needs reappraisal. The ...

journal_title：Experimental physiology

authors： Parkes MJ

更新日期：2017-12-01 00:00:00

abstract：:A video-laryngoscopic method, implemented with an algorithm for the correction of the deformation inherent in the endoscope optical system, has been used to measure the dorsoventral diameter (Drg) and the cross-sectional area (CSArg) of the rima glottidis in five healthy workhorses during conscious breathing at rest. ...

journal_title：Experimental physiology

authors： Lafortuna CL,Albertini M,Ferrucci F,Zucca E,Braghieri M,Clement MG,Saibene F

更新日期：1999-07-01 00:00:00

abstract：:The effects of 5 weeks of moderate-intensity endurance training on pulmonary oxygen uptake kinetics (V(O(2)) on-kinetics) were studied in 15 healthy men (mean ± SD: age 22.7 ± 1.8 years, body weight 76.4 ± 8.9 kg and maximal V(O(2)) 46.0 ± 3.7 ml kg(-1) min(-1)). Training caused a significant acceleration (P = 0.003) ...

journal_title：Experimental physiology

authors： Zoladz JA,Grassi B,Majerczak J,Szkutnik Z,Korostyński M,Karasiński J,Kilarski W,Korzeniewski B

更新日期：2013-04-01 00:00:00

abstract：:Preparations of isolated rat jejunal enterocyte and brush-border and basolateral membrane vesicles have been used to study the effects of a 15 min exposure of upper and mid-villus enterocytes to pancreatic glucagon on the initial, unidirectional phlorhizin-sensitive (brush border) transport of galactose and phlorhizin...

journal_title：Experimental physiology

authors： Debnam ES,Sharp PA

更新日期：1993-03-01 00:00:00