Abstract:
:After food is ingested, nutrients pass through the gastrointestinal tract, stimulating the release of a range of peptide hormones. Among their many local, central and peripheral actions, these hormones act to mediate glucose metabolism and satiety. Indeed, it is the modification of gut hormone secretion that is considered partly responsible for the normalization of glycaemic control and the reduction in appetite seen in many patients after certain forms of bariatric surgery. This review describes recent developments in our understanding of the secretion and action of anorexigenic gut hormones, primarily concentrating on glucagon-like peptide-1 (GLP-1).
journal_name
Exp Physioljournal_title
Experimental physiologyauthors
Parker HE,Gribble FM,Reimann Fdoi
10.1113/expphysiol.2014.079764subject
Has Abstractpub_date
2014-09-01 00:00:00pages
1116-20issue
9eissn
0958-0670issn
1469-445Xpii
99/9/1116journal_volume
99pub_type
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