Abstract:
:In this review we discuss our current understanding of the cellular basis of uterine contractility, highlighting those areas requiring further study. It is clear that the basic processes of excitation-contraction coupling lie within the myometrial cell, and that these may be modified by agonists. Pacemaker activity, however, remains a mystery. The contribution of extracellular calcium entry to contraction is shown to be vital, whilst the role of the sarcoplasmic reticulum remains controversial. Much current experimental focus is on pathways controlling and regulating contraction, and we discuss sensitisation mechanisms and question their role in intact uterine preparations. Experimental Physiology (2001) 86.2, 239-246.
journal_name
Exp Physioljournal_title
Experimental physiologyauthors
Wray S,Kupittayanant S,Shmygol A,Smith RD,Burdyga Tdoi
10.1113/eph8602114subject
Has Abstractpub_date
2001-03-01 00:00:00pages
239-46issue
2eissn
0958-0670issn
1469-445Xpii
EPH_2114journal_volume
86pub_type
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journal_title:Experimental physiology
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abstract:NEW FINDINGS:What is the central question of this study? We modelled the alveolar pathway during breath holding on the hypothesis that it follows a hypoventilation loop on the O2 -CO2 diagram. What is the main finding and its importance? Validation of the model was possible within the range of alveolar gas compositions...
journal_title:Experimental physiology
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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doi:
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abstract::What is the central question of this study? Failure to terminate apnoea and arouse is likely to contribute to sudden infant death syndrome (SIDS). Serotonin is deficient in the brainstems of babies who died of SIDS. Therefore, we tested the hypothesis that serotonin in the nucleus of the solitary tract (NTS) would sho...
journal_title:Experimental physiology
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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更新日期:2017-03-01 00:00:00
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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