Evolution of contractile and elastic properties of rat soleus muscle fibres under unloading conditions.

abstract：:The uptake and distribution of CO throughout the circulatory system during two different methods of CO rebreathing (2 min 'Schmidt' and 40 min 'Burge' methods) were determined in nine healthy volunteers. Specifically, the impact of (i) differences in circulatory mixing time (t(mix)), (ii) CO diffusion to myoglobin (Mb...

journal_title：Experimental physiology

authors： Garvican LA,Burge CM,Cox AJ,Clark SA,Martin DT,Gore CJ

更新日期：2010-12-01 00:00:00

abstract：:In anaesthetized cats, reflex respiratory responses were evoked by electrically stimulating proximal ends of cut nerves to gastrocnemius-soleus muscles of the left hindlimb. The direction of these responses, in the excitatory or inhibitory sense, depended on the types of afferent fibres stimulated and on the mode of s...

journal_title：Experimental physiology

authors： Decandia M,Orani GP

更新日期：1995-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Quantitative values of shear rate-specific blood viscosity and shear stress in the human macrovasculature in response to exercise hyperaemia are unknown. What is the main finding and its importance? Using the handgrip exercise model, we showed that an increase in...

journal_title：Experimental physiology

authors： Leo JA,Simmonds MJ,Sabapathy S

更新日期：2020-02-01 00:00:00

abstract：:Early vascular changes at the molecular level caused by adoption of a sedentary lifestyle are incompletely characterized. Herein, we employed the rodent wheel-lock model to identify mRNAs in the arterial wall that are responsive to the acute transition from higher to lower levels of daily physical activity. Specifical...

journal_title：Experimental physiology

authors： Padilla J,Jenkins NT,Roberts MD,Arce-Esquivel AA,Martin JS,Laughlin MH,Booth FW

更新日期：2013-01-01 00:00:00

abstract：:The purpose of the present study was to investigate the effect of temperature on the rates of isometric force development and relaxation in electrically activated fresh and fatigued human adductor pollicis muscle. Following immersion of the lower arm for 20 min in water baths of four different temperatures, muscle tem...

journal_title：Experimental physiology

authors： de Ruiter CJ,Jones DA,Sargeant AJ,de Haan A

更新日期：1999-11-01 00:00:00

abstract：:In vivo microperfusion techniques were used to investigate the role of Na+-H+ exchange in the efferent ducts of the rat. Individual efferent ducts were perfused with a Krebs-Ringer bicarbonate solution (KRB) containing 0, 1, 3, 5 or 7.5 mM amiloride. Concentrations of 1-5 mM amiloride inhibited fluid reabsorption from...

journal_title：Experimental physiology

authors： Hansen LA,Clulow J,Jones RC

更新日期：1999-05-01 00:00:00

abstract：:Spermine is a low molecular weight polyamine involved in the postnatal maturation of the gut. When it is administered orally to suckling rats, it induces maturation of the intestinal tract (liver, pancreas and small intestine). Here we show that this polyamine is able to induce precocious intestinal and splenic develo...

journal_title：Experimental physiology

authors： Jolois O,Peulen O,Collin S,Simons M,Dandrifosse G,Heinen E

更新日期：2002-01-01 00:00:00

abstract：:Hypertension caused by chronic infusion of angiotensin II (Ang II) in experimental animals is likely to be mediated, at least in part, by an elevation of ongoing sympathetic nerve activity (SNA). However, the contribution of SNA relative to non-neural mechanisms in mediating Ang II-induced hypertension is an area of i...

journal_title：Experimental physiology

authors： Toney GM,Pedrino GR,Fink GD,Osborn JW

更新日期：2010-05-01 00:00:00

abstract：:The sympathetic neural regulation of the cerebral circulation remains controversial. The purpose of the present study was to determine how exercise modulates the simultaneous responsiveness of the cerebral and brachial circulations to 'endogenous' sympathetic activation (cold pressor test). In nine healthy subjects, h...

journal_title：Experimental physiology

authors： Hartwich D,Fowler KL,Wynn LJ,Fisher JP

更新日期：2010-11-01 00:00:00

abstract：:In anaesthetized cats, it was possible to enhance the dynamic sensitivity to stretch of jaw muscle spindle primary afferents by electrical stimulation in the midbrain. This effect was taken to be due to excitation of dynamic fusimotor neurones and was used to identify fusimotor fibres as static or dynamic in recording...

journal_title：Experimental physiology

authors： Donga R,Taylor A,Jüch PJ

更新日期：1993-01-01 00:00:00

abstract：:What is the central question of this study? Can a modern proportional assist ventilator (PAV) function sufficiently well to unload the respiratory muscles during exercise? What is the main finding and its importance? A PAV can be constructed with contemporary hardware and software and be used at all exercise intensiti...

journal_title：Experimental physiology

authors： Dominelli PB,Henderson WR,Sheel AW

更新日期：2016-06-01 00:00:00

abstract：:Luminal fluids were collected in vivo by micropuncture and cannulation from the rete testis, efferent ducts and ductus epididymidis of the rat to determine the composition of efferent duct fluids and the rates of reabsorption of water and solutes by the efferent ducts. The concentration of spermatozoa increased by a f...

journal_title：Experimental physiology

authors： Clulow J,Jones RC,Hansen LA

更新日期：1994-11-01 00:00:00

abstract：:Rat hippocampal neurones in primary culture exhibited directional growth in response to DC electric fields. Neurites lay perpendicular to the field after exposure to 28, 80 or 219 mV/mm but there was no orientation effect at 9 mV/mm or in unexposed control cultures. Fields that evoked perpendicular responses also redu...

journal_title：Experimental physiology

authors： Rajnicek AM,Gow NA,McCaig CD

更新日期：1992-01-01 00:00:00

abstract：:This study investigated the role of nitric oxide (NO) and superoxide anions in modulating the renal nerve-dependent increases in proximal tubular fluid reabsorption (Jva). Renal nerve stimulation at 0.75 and 1.0 Hz (15 V, 0.2 ms) in anaesthetized Wistar rats had no effect on glomerular filtration rate but decreased ur...

journal_title：Experimental physiology

authors： Wu XC,Johns EJ

更新日期：2004-05-01 00:00:00

abstract：:The effects of modification of the levels of endogenous plasma insulin on intestinal epithelial cell proliferation were investigated in rats maintained by total parenteral nutrition (TPN) using either a TPN diet that was high in glucose, or a low glucose (hypocaloric) TPN diet and in orally fed rats (normal and sham o...

journal_title：Experimental physiology

authors： Goodlad RA,Lee CY,Gilbey SG,Ghatei MA,Bloom SR

更新日期：1993-09-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? The manuscript collectively combines the experimental observations from >100 publications focusing on the regulation of cerebral blood flow and metabolism during exercise from 1945 to the present day. What advances does it highlight? This article highlights the importance ...

journal_title：Experimental physiology

authors： Smith KJ,Ainslie PN

更新日期：2017-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Loss of taste or inability to distinguish between different tastes progresses with age. The purpose was to evaluate the age-dependent changes in taste by studying the electrophysiological properties of taste receptor cells. What is the main finding and its import...

journal_title：Experimental physiology

authors： Takeuchi K,Yoshii K,Ohtubo Y

更新日期：2020-11-10 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? The sympathetic control of renal sodium tubular reabsorption is dependent on activation of the intrarenal renin-angiotensin system and activation of the angiotensin II type 1 (AT1 ) receptor by angiotensin II. What advances does it highlight? Despite the fact that the inte...

journal_title：Experimental physiology

authors： Pontes RB,Girardi AC,Nishi EE,Campos RR,Bergamaschi CT

更新日期：2015-04-20 00:00:00

abstract：:This work was undertaken to study the effect of pectin feeding on the expression level, cellular localization and functional activity of monocarboxylate transporter 1 (MCT1) in the gastrointestinal tract of rats. The results indicated that MCT1 protein level was significantly increased along the entire length of the g...

journal_title：Experimental physiology

authors： Kirat D,Kondo K,Shimada R,Kato S

更新日期：2009-04-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the ultrastructural changes of the caecal mucosa and the status of epithelial cellular apoptosis and oxidative reactions in lactating goats after prolonged feeding with a high-concentrate diet? What is the main finding and its importance? High-concentrat...

journal_title：Experimental physiology

authors： Tao S,Tian J,Cong R,Sun L,Duanmu Y,Dong H,Ni Y,Zhao R

更新日期：2015-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Hypoxic pulmonary vasoconstriction has never been characterized in isolated mouse pulmonary arteries of different generations in detail. What is the main finding and its importance? We found that only small intrapulmonary arteries (80-200 μm in diameter) exhibit ...

journal_title：Experimental physiology

authors： Strielkov I,Krause NC,Sommer N,Schermuly RT,Ghofrani HA,Grimminger F,Gudermann T,Dietrich A,Weissmann N

更新日期：2018-09-01 00:00:00

abstract：:An energy-rich diet leads to enhanced ruminal Na(+) absorption, which is associated with elevated plasma insulin-like growth factor 1 (IGF-1) levels and an increased number of IGF-1 receptors in rumen papillae. This study examined the in vitro effect of IGF-1 on Na(+) transport across the rumen epithelium of hay-fed s...

journal_title：Experimental physiology

authors： Shen Z,Martens H,Schweigel-Röntgen M

更新日期：2012-04-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Can targeted ablation of cardiac sympathetic neurons suppress myocardial infarction-induced adverse cardiac remodelling and left ventricular dysfunction? What is the main finding and its importance? Targeted ablation of cardiac sympathetic neurons significantly a...

journal_title：Experimental physiology

authors： Xiong L,Liu Y,Zhou M,Wang G,Quan D,Shuai W,Shen C,Kong B,Huang C,Huang H

更新日期：2018-09-01 00:00:00

abstract：:Progressive asphyxia, produced by a prolonged voluntary breath hold (end-expiratory apnoea), evokes large bursts of muscle sympathetic nerve activity (MSNA). These bursts increase in amplitude until the asphyxic break point is reached, at which point the bursts are inhibited. We tested the hypothesis that lung inflati...

journal_title：Experimental physiology

authors： Seitz MJ,Brown R,Macefield VG

更新日期：2013-02-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Do changes in levels of angiogenesis-related mediators [vascular endothelial growth factor-A (VEGF-A), thrombospondin-1 (TSP-1) and nuclear factor-κB (NF-κB)] in the sciatic nerve mediate diabetic neuropathy in the streptozotocin-induced type 1 diabetic male rat?...

journal_title：Experimental physiology

authors： Saboory E,Gholizadeh-Ghaleh Aziz S,Samadi M,Biabanghard A,Chodari L

更新日期：2020-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Research has reported that some sensory input, such as auditory and olfactory input, can affect subliminal visual processing. However, it is important to address whether tactile input, another form of elementary sensory input, could influence the interocular riva...

journal_title：Experimental physiology

authors： Lang Y,Gao M,Huang Q,Liu Z,Wu L,Tang R

更新日期：2019-11-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This article draws evidence from the current literature to support the hypothesis that non-coding RNA-mediated gene regulation takes place in the mitochondria. An emphasis is put on skeletal muscle. What advances does it highlight? This review highlights the potential role...

journal_title：Experimental physiology

authors： Silver J,Wadley G,Lamon S

更新日期：2018-08-01 00:00:00

abstract：:To better understand the mechanisms underlying the pulmonary O(2) uptake (V(O(2P))) slow component during high-intensity exercise, we used (31)P magnetic resonance spectroscopy, gas exchange, surface electromyography and near-infrared spectroscopy measurements to examine the potential relationship between the slow com...

journal_title：Experimental physiology

authors： Layec G,Bringard A,Yashiro K,Le Fur Y,Vilmen C,Micallef JP,Perrey S,Cozzone PJ,Bendahan D

更新日期：2012-08-01 00:00:00

abstract：:What is the central question of this study? Neurocognitive functions can be enhanced by acute aerobic exercise, which could be associated with changes in serum brain-derived neurotrophic factor (BDNF) concentrations. We aimed to explore acute exercise-induced changes in BDNF concentrations, neuropsychological and neur...

journal_title：Experimental physiology

authors： Tsai CL,Pan CY,Chen FC,Wang CH,Chou FY

更新日期：2016-07-01 00:00:00

abstract：:The endothelial glycocalyx layer of capillaries was stained with Ruthenium Red and examined by transmission electron microscopy in rat extensor hallucis proprius muscles after 2 or 4 days of indirect electrical stimulation via implanted electrodes. The layer appeared continuous on the luminal surface of 63% capillarie...

journal_title：Experimental physiology

authors： Brown MD,Egginton S,Hudlicka O,Zhou AL

更新日期：1996-11-01 00:00:00