Abstract:
:Rat hippocampal neurones in primary culture exhibited directional growth in response to DC electric fields. Neurites lay perpendicular to the field after exposure to 28, 80 or 219 mV/mm but there was no orientation effect at 9 mV/mm or in unexposed control cultures. Fields that evoked perpendicular responses also reduced the number of cathode-facing neurites. Orientation was the same for neurite initiation sites and the direction of overall neurite growth.
journal_name
Exp Physioljournal_title
Experimental physiologyauthors
Rajnicek AM,Gow NA,McCaig CDdoi
10.1113/expphysiol.1992.sp003580subject
Has Abstractpub_date
1992-01-01 00:00:00pages
229-32issue
1eissn
0958-0670issn
1469-445Xjournal_volume
77pub_type
杂志文章abstract:NEW FINDINGS:What is the central question of this study? The aim was to determine the effect of mid-portion Achilles tendinopathy (MAT) on free Achilles tendon three-dimensional morphology and volume at rest and under load in people with unilateral MAT. What is the main finding and its importance? Tendinopathic tendon ...
journal_title:Experimental physiology
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journal_title:Experimental physiology
pub_type: 杂志文章,评审
doi:10.1113/expphysiol.2008.043349
更新日期:2009-03-01 00:00:00
abstract::Changes in tension of slow motor units in the medial gastrocnemius muscle of the rat were measured and compared in three fatigue tests, each of 4 min duration. In one of these tests motor unit tetani were evoked by repeated trains of stimuli of the standard frequency, 40 Hz, while in other tests frequencies of 20 and ...
journal_title:Experimental physiology
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abstract::The effects of exogenous arginine vasotocin (AVT), isotocin (IT) and melatonin on the blood pressure of conscious Atlantic cod (Gadus morhua) were examined. Ventral aortic blood pressure (PVA) was recorded from a cannula inserted into the afferent branchial artery of the third gill arch. Dorsal aortic blood pressure (...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.1998.sp004161
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abstract:NEW FINDINGS:What is the central question of this study? What factors influence the onset and magnitude of activation of the neck inspiratory muscles during inspiration? What is the main finding and its importance? Recruitment of the sternocleidomastoid and scalene muscles during inspiration, measured by means of surfa...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/EP087247
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abstract::This study investigated the role of nitric oxide (NO) and superoxide anions in modulating the renal nerve-dependent increases in proximal tubular fluid reabsorption (Jva). Renal nerve stimulation at 0.75 and 1.0 Hz (15 V, 0.2 ms) in anaesthetized Wistar rats had no effect on glomerular filtration rate but decreased ur...
journal_title:Experimental physiology
pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
abstract::Neural activation decreases cerebral deoxyhaemoglobin (HHb(C)) and increases oxyhaemoglobin concentration (O(2)Hb(C)). In contrast, patients who present with restricted cerebral blood flow, such as those suffering from cerebral ischaemia or Alzheimer's disease, and during the course of ageing the converse occurs, in t...
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journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.2007.040485
更新日期:2008-03-01 00:00:00
abstract::A recent model predicted a local synovial circulation of extravascular fluid in which capillary filtrate entered a joint cavity and fluid simultaneously drained out of the cavity via intercellular pathways distant from capillaries. Here, solutions of albumin (10-250 g l-1) were infused continuously into the knee joint...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.1992.sp003613
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journal_title:Experimental physiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Lower body negative pressure (LBNP) reduces central venous pressure (CVP) and cardiac output. The elderly are reported to have a limited capacity to increase cardiac output by increasing heart rate (HR), are especially dependent on end diastolic volume to maintain stroke volume and therefore should be especially vulne...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/eph8602153
更新日期:2001-05-01 00:00:00
abstract::The effect of unilateral Achilles' tendon section on the soleus muscle of rabbits was examined after 2 and 4 weeks of unsutured recovery. Immobilization of the limb during recovery was also investigated. Following tendon section the limb was immobilized with an ankle angle of 90 deg, and final experiments were perform...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.1994.sp003784
更新日期:1994-07-01 00:00:00
abstract::Hypertension caused by chronic infusion of angiotensin II (Ang II) in experimental animals is likely to be mediated, at least in part, by an elevation of ongoing sympathetic nerve activity (SNA). However, the contribution of SNA relative to non-neural mechanisms in mediating Ang II-induced hypertension is an area of i...
journal_title:Experimental physiology
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journal_title:Experimental physiology
pub_type: 杂志文章,评审
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更新日期:2005-05-01 00:00:00
abstract::The present study investigated the absolute reliability (R(Ab)) of isometric measures of time-to-peak tension (TTP), half-rise time ((1/2)RT), half-fall time ((1/2)FT), twitch force (TW(f)) tetanic force (TET(f)) and the sag ratio as applied to the slow soleus (SOL) and the fast-twitch extensor digitorum longus (EDL) ...
journal_title:Experimental physiology
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pub_type: 杂志文章
doi:10.1113/EP088354
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abstract::Ionic mechanisms and signal transduction underlying noradrenaline (NA)-induced depolarization in single smooth muscle cells of guinea-pig vas deferens were studied. NA caused depolarization followed by action potentials through activation of 1-adrenoceptors. In the presence of nifedipine, no action potential was gener...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:NEW FINDINGS:What is the central question of this study? Regulation of cardiac function is typically achieved by changes in heart rate (HR) and cardiac shortening velocity (strain rate; SR), but their interdependence in vivo remains poorly understood. What is the main finding and its importance? Using resistance exerci...
journal_title:Experimental physiology
pub_type: 杂志文章,评审
doi:10.1113/EP085081
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journal_title:Experimental physiology
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doi:10.1113/expphysiol.2012.066365
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journal_title:Experimental physiology
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abstract:NEW FINDINGS:What is the topic of this review? We discuss tools available to access genome-wide data sets that harbour cell-specific, brain region-specific and tissue-specific information on exon usage for several species, including humans. In this Review, we demonstrate how to access this information in genome databas...
journal_title:Experimental physiology
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abstract::Cardiovascular arousal is associated with patterned cortical activity changes. Head-down-tilt bed rest (HDBR) dimishes the baroreflex-mediated cardiac control. The present study tested the hypothesis that HDBR deconditioning would modify the forebrain organization for heart rate (HR) control during baroreflex unloadin...
journal_title:Experimental physiology
pub_type: 杂志文章,随机对照试验
doi:10.1113/expphysiol.2012.065557
更新日期:2012-12-01 00:00:00
abstract::Interdigestive intestinal motility, and especially phase III of the migrating myoelectric/motor complex (MMC), is responsible for intestinal clearance and plays an important role in prevention of bacterial overgrowth and translocation in the gut. Yet previous results from gnotobiotic rats have shown that intestinal mi...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.2005.031708
更新日期:2006-01-01 00:00:00
abstract::The physiological mechanisms contributing to sex differences following myocardial infarction (MI) are poorly understood. Given the strong relationship between sympathetic nerve activity (SNA) and outcome, we hypothesized there may be a sex difference in SNA responses to MI. In anaesthetized, open-chest male, female an...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.2012.065615
更新日期:2012-09-01 00:00:00
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journal_title:Experimental physiology
pub_type: 临床试验,杂志文章
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更新日期:2012-03-01 00:00:00
abstract::Indirect evidence supporting a solute-coupled liquid absorption from the pleural space of rabbits has recently been provided; moreover, the beta 2-adrenoceptor agonist terbutaline has been found to increase this absorption. In this study the effect of adrenaline and alpha-adrenoceptor agonists on net rate of liquid ab...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/expphysiol.1997.sp004043
更新日期:1997-05-01 00:00:00
abstract::Gastric distension in anaesthetized pigs reflexly elicits peripheral vasoconstriction and an increase in plasma renin activity (PRA), with vagal afferent and sympathetic efferent limbs. The aim of the present study was to quantify the contribution of the renin-angiotensin system to the peripheral vasoconstriction. In ...
journal_title:Experimental physiology
pub_type: 杂志文章
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journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1111/j.1469-445x.2000.02048.x
更新日期:2000-11-01 00:00:00
abstract:NEW FINDINGS:What is the central question of this study? What are the molecular underpinnings of seasonal metabolic plasticity during spring and autumn migrations in songbirds? What is the main finding and its importance? We report differences in mRNA levels of genes involved in the regulation of glucose and fat metabo...
journal_title:Experimental physiology
pub_type: 杂志文章
doi:10.1113/EP087974
更新日期:2019-12-01 00:00:00