Abstract:
:A 26-year-old Japanese woman developed autoimmune pulmonary alveolar proteinosis (PAP) during glucocorticoid therapy for systemic lupus erythematosus (SLE). Intensive immunosuppressive therapy worsened the PAP. De-escalation of immunosuppressive therapy improved the PAP. Autoimmune PAP is rarely associated with systemic autoimmune diseases, and the present case is the first case of autoimmune PAP associated with SLE. Moreover, the present case suggests that immunosuppressive therapy should be avoided or used carefully for the treatment of patients with anti-GM-CSF antibody, such as those with autoimmune PAP.
journal_name
Lupusjournal_title
Lupusauthors
Nagasawa J,Kurasawa K,Maezawa R,Owada T,Hanaoka R,Fukuda Tdoi
10.1177/0961203313498798subject
Has Abstractpub_date
2013-09-01 00:00:00pages
1060-3issue
10eissn
0961-2033issn
1477-0962pii
0961203313498798journal_volume
22pub_type
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