Anti-oxidant enzymes in Cryptosporidium parvum oocysts.

Abstract:

:Oocysts of Cryptosporidium parvum showed relatively low levels of SOD activity. The SOD which had a pI of 4.8 and an approximate molecular weight of 35 kDa appeared to be iron dependent. Catalase, glutathione transferase, glutathione reductase and glutathione peroxidase activity could not be detected, nor could trypanothione reductase. No NADH or NADPH oxidase activity could be detected, nor could peroxidase activity be demonstrated using o-dianisidine, guaiacol, NADPH or NADH as co-substrates. However, an NADPH-dependent H2O2 scavenging system was detected in the insoluble fraction.

journal_name

Parasitology

journal_title

Parasitology

authors

Entrala E,Mascaro C,Barrett J

doi

10.1017/s0031182096008037

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

13-7

eissn

0031-1820

issn

1469-8161

journal_volume

114 ( Pt 1)

pub_type

杂志文章
  • Changes in metabolism and behaviour of the freshwater copepod Cyclops strenuus abyssorum infected with Diphyllobothrium spp.

    abstract::In a population of copepods (Cyclops strenuus abyssorum), with a naturally high prevalence of infection with procercoids of Diphyllobothrium spp., no difference in body size was found between infected and uninfected hosts. However, a significant reduction in the reproductive capacity of infected females was observed, ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000064738

    authors: Pasternak AF,Huntingford FA,Crompton DW

    更新日期:1995-05-01 00:00:00

  • Estimating phylogenetic relationships despite discordant gene trees across loci: the species tree of a diverse species group of feather mites (Acari: Proctophyllodidae).

    abstract::With the increased availability of multilocus sequence data, the lack of concordance of gene trees estimated for independent loci has focused attention on both the biological processes producing the discord and the methodologies used to estimate phylogenetic relationships. What has emerged is a suite of new analytical...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118201100031X

    authors: Knowles LL,Klimov PB

    更新日期:2011-11-01 00:00:00

  • Tracking a heterosis effect in the field: tadpole resistance to parasites in the water frog hybridogenetic complex.

    abstract::Depending on the extent of evolutionary divergence among parent taxa, hybrids may suffer from a breakdown of co-adapted genes or may conversely exhibit vigour due to the heterosis effect, which confers advantages to increased genetic diversity. That last mechanism could explain the success of hybrids when hybridizatio...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009006489

    authors: Planade B,Lena JP,Li H,Plenet S,Guegan JF,Thomas F,Hurtrez-Bousses S,Renaud F,Joly P

    更新日期:2009-08-01 00:00:00

  • Parasite-specific antibody responses of ruminants infected with Trypanosoma vivax.

    abstract::Sera from goats and cattle that were infected with two Trypanosoma vivax clones (ILDat 1.2 and ILDat 2.1) derived from different stocks were analysed for antibody activity against the variable surface glycoproteins (VSGs) of the infecting clones by enzyme-linked immune assays (ELISA) and immune lysis. To obtain purifi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000060157

    authors: Vos GJ,Gardiner PR

    更新日期:1990-02-01 00:00:00

  • Profilicollis botulus (Acanthocephala) abundance in the eider duck (Somateria mollissima) on the Ythan estuary, Aberdeenshire.

    abstract::The abundance of Profilicollis botulus was monitored in eider ducks for 3 years. No significant difference in P. botulus abundance was found between eiders taken alive and those collected dead from the shore line, or between adult males and adult females. Adult male eiders had a seasonal pattern of infection. Incubati...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000062806

    authors: Thompson AB

    更新日期:1985-12-01 00:00:00

  • Evidence that primary infection of Charollais sheep with Toxoplasma gondii may not prevent foetal infection and abortion in subsequent lambings.

    abstract::A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182007003721

    authors: Morley EK,Williams RH,Hughes JM,Thomasson D,Terry RS,Duncanson P,Smith JE,Hide G

    更新日期:2008-02-01 00:00:00

  • Heterogeneity of metalloprotease expression in Trypanosoma cruzi.

    abstract::Expression of metalloprotease activities during metacyclogenesis of a series of strains and clones of Trypanosoma cruzi was investigated using SDS-polyacrylamide gel electrophoresis with a range of different co-polymerized proteolytic substrates. A complex pattern of metalloprotease expression, with considerable quant...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000066622

    authors: Lowndes CM,Bonaldo MC,Thomaz N,Goldenberg S

    更新日期:1996-04-01 00:00:00

  • Triggering and modulation of the host-parasite interplay by Echinococcus multilocularis: a review.

    abstract::As more facts emerge regarding the ways in which E. multilocularis-derived molecules trigger the host immune response and modulate the host-parasite interplay, it becomes possible to envisage how the parasite can survive and proliferate in its intermediate host, while in other hosts it dies out. Through effects on cel...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182009991533

    authors: Mejri N,Hemphill A,Gottstein B

    更新日期:2010-03-01 00:00:00

  • Simple epidemiological model predicts the relationships between prevalence and abundance in ixodid ticks.

    abstract::We tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. We used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (Apodemus agrarius, Apodemus flavicollis...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182006001296

    authors: Stanko M,Krasnov BR,Miklisova D,Morand S

    更新日期:2007-01-01 00:00:00

  • Structure of three high voltage-activated calcium channel alpha1 subunits from Schistosoma mansoni.

    abstract::Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001008691

    authors: Kohn AB,Lea J,Roberts-Misterly JM,Anderson PA,Greenberg RM

    更新日期:2001-11-01 00:00:00

  • CYP51 as drug targets for fungi and protozoan parasites: past, present and future.

    abstract::The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post-cancer patients often exceed 50%. A set of six systemic clinical azol...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182018000562

    authors: Lepesheva GI,Friggeri L,Waterman MR

    更新日期:2018-12-01 00:00:00

  • The molecular systematics of blowflies and screwworm flies (Diptera: Calliphoridae) using 28S rRNA, COX1 and EF-1α: insights into the evolution of dipteran parasitism.

    abstract::The Calliphoridae include some of the most economically significant myiasis-causing flies in the world - blowflies and screwworm flies - with many being notorious for their parasitism of livestock. However, despite more than 50 years of research, key taxonomic relationships within the family remain unresolved. This st...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182011001089

    authors: McDonagh LM,Stevens JR

    更新日期:2011-11-01 00:00:00

  • An enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to Encephalitozoon cuniculi and its use in determination of infections in man.

    abstract::An enzyme-linked immunosorbent assay (ELISA) was used to detect antibodies to Encephalitozoon cuniculi in man, using spores derived from tissue culture as antigen. Negligible cross-reactions were found with other microsporidia of vertebrate or of invertebrate origin and there was no cross-reaction with Toxoplasma gond...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000053890

    authors: Hollister WS,Canning EU

    更新日期:1987-04-01 00:00:00

  • A comparison of the surface and secretions of Trichinella pseudospiralis and T. spiralis.

    abstract::Intact, viable adults, infective and newborn larvae of Trichinella pseudospiralis were surface labelled with 125I by the chloramine T method and labelled proteins were compared with those obtained from equivalent stages of T. spiralis. Electron-microscope autoradiography determined that labelled proteins were restrict...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200004991x

    authors: Almond NM,McLaren DJ,Parkhouse RM

    更新日期:1986-08-01 00:00:00

  • Attraction behaviour of three entomopathogenic nematode species towards infected and uninfected hosts.

    abstract::Entomopathogenic nematode infective juveniles are likely to encounter both uninfected and infected insects and host quality depends on the stage of the infection. We hypothesized that nematode response to infected hosts will change over the course of an infection. Here, we tested this hypothesis by focusing on the inf...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182006001880

    authors: Ramos-Rodríguez O,Campbell JF,Christen JM,Shapiro-Ilan DI,Lewis EE,Ramaswamy SB

    更新日期:2007-05-01 00:00:00

  • An introduced pentastomid parasite (Raillietiella frenata) infects native cane toads (Rhinella marina) in Panama.

    abstract::The pentastomid parasite, Raillietiella frenata, is native to Asia where it infects the Asian House gecko, Hemidactylus frenatus. This gecko has been widely introduced and recently R. frenata was found in introduced populations of cane toads (Rhinella marina) in Australia, indicating a host-switch from introduced geck...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182014001759

    authors: Kelehear C,Saltonstall K,Torchin ME

    更新日期:2015-04-01 00:00:00

  • Small RNAs in parasitic nematodes - forms and functions.

    abstract::Small RNAs are important regulators of gene expression. They were first identified in Caenorhabditis elegans, but it is now apparent that the main small RNA silencing pathways are functionally conserved across diverse organisms. Availability of genome data for an increasing number of parasitic nematodes has enabled bi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182019001689

    authors: Britton C,Laing R,Devaney E

    更新日期:2020-07-01 00:00:00

  • Selection and evolution of virulence in bacteria: an ecumenical excursion and modest suggestion.

    abstract::Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s0031182000073054

    authors: Levin BR,Svanborg Edén C

    更新日期:1990-01-01 00:00:00

  • Detection of eight Cryptosporidium genotypes in surface and waste waters in Europe.

    abstract::Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001001317

    authors: Ward PI,Deplazes P,Regli W,Rinder H,Mathis A

    更新日期:2002-04-01 00:00:00

  • Experimental combination therapy using low doses of benznidazole and allopurinol in mouse models of Trypanosoma cruzi chronic infection.

    abstract::This study evaluated the effectiveness of low doses of benznidazole (BNZ) on continuous administration (BNZc), combined with allopurinol (ALO), in C57BL/6J and C3H/HeN mice infected with Trypanosoma cruzi Nicaragua strain and T. cruzi Sylvio-X10/4 clone. TcN-C57BL/6J was also treated with intermittent doses of BNZ (BN...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182018001567

    authors: Rial MS,Scalise ML,López Alarcón M,Esteva MI,Búa J,Benatar AF,Prado NG,Riarte AR,Fichera LE

    更新日期:2019-03-01 00:00:00

  • Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro.

    abstract::We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus. Within a 2 h incubation period, all the cysteine proteinases, with the exceptio...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004006225

    authors: Stepek G,Buttle DJ,Duce IR,Lowe A,Behnke JM

    更新日期:2005-02-01 00:00:00

  • The reproductive effort of Lepeophtheirus pectoralis (Copepoda: Caligidae): insights into the egg production strategy of parasitic copepods.

    abstract::The reproductive effort of Lepeophtheirus pectoralis (Müller O. F., 1776), a caligid copepod, which is commonly found infecting the European flounder, Platichthys flesus (Linnaeus, 1758), is studied in detail for the first time. Seasonal variation in body dimensions and reproductive effort are analysed. Data for 120 o...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182015001493

    authors: Frade DG,Santos MJ,Cavaleiro FI

    更新日期:2016-01-01 00:00:00

  • RNA-interference methods for gene-knockdown in the sea louse, Lepeophtheirus salmonis: studies on a putative prostaglandin E synthase.

    abstract::Harnessing the full utility of extensive gene sequences recently available for the economically important sea louse, Lepeophtheirus salmonis, requires the adaptation of modern molecular biology approaches to this non-model organism. Using a putative microsomal prostaglandin E synthase type-2 (PGES2) as a candidate gen...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009990357

    authors: Campbell EM,Pert CC,Bowman AS

    更新日期:2009-07-01 00:00:00

  • Isolation, fractionation and partial characterization of the tegumental surface from protoscoleces of the hydatid organism, Echinococcus granulosus.

    abstract::Several approaches were adopted for the disruption and removal of the tegumental surface from protoscoleces of the horse strain of the hydatid organism, Echinococcus granulosus. The effectiveness of each method and the purity of subsequent microthrix-enriched fractions obtained by differential centrifugation were eval...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000049064

    authors: McManus DP,Barrett NJ

    更新日期:1985-02-01 00:00:00

  • A role for antimicrobial peptides in intestinal microsporidiosis.

    abstract:SUMMARY:Clinical isolates from 3 microsporidia species, Encephalitozoon intestinalis and Encephalitozoon hellem, and the insect parasite Anncaliia (Brachiola, Nosema) algerae, were used in spore germination and enterocyte-like (C2Bbe1) cell infection assays to determine the effect of a panel of antimicrobial peptides. ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182008005313

    authors: Leitch GJ,Ceballos C

    更新日期:2009-02-01 00:00:00

  • Trypanosoma cruzi heparin-binding proteins present a flagellar membrane localization and serine proteinase activity.

    abstract::Heparin-binding proteins (HBPs) play a key role in Trypanosoma cruzi-host cell interactions. HBPs recognize heparan sulfate (HS) at the host cell surface and are able to induce the cytoadherence and invasion of this parasite. Herein, we analysed the biochemical properties of the HBPs and also evaluated the expression ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182012001448

    authors: Oliveira FO Jr,Alves CR,Silva FS,Côrtes LM,Toma L,Bouças RI,Aguilar T,Nader HB,Pereira MC

    更新日期:2013-02-01 00:00:00

  • Cellular and biochemical characterization of two closely related triosephosphate isomerases from Trichomonas vaginalis.

    abstract::The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118201200114X

    authors: Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

    更新日期:2012-11-01 00:00:00

  • Evaluation of salinomycin isolated from Streptomyces albus JSY-2 against the ciliate, Ichthyophthirius multifiliis.

    abstract::The present study was undertaken to investigate the antiparasitic activity of extracellular products of Streptomyces albus. Bioactivity-guided isolation of chloroform extracts affording a compound showing potent activity. The structure of the compound was elucidated as salinomycin (SAL) by EI-MS, 1H NMR and 13C NMR. I...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182018001919

    authors: Yao JY,Gao MY,Jia YY,Wu YX,Yin WL,Cao Z,Yang GL,Huang HB,Wang CF,Shen JY,Gu ZM

    更新日期:2019-04-01 00:00:00

  • Trypanosoma brucei spp. development in the tsetse fly: characterization of the post-mesocyclic stages in the foregut and proboscis.

    abstract::Post-mesocyclic development of Trypanosoma brucei in the tsetse fly in its migration from midgut to salivary glands, was revisited by sequential microdissection, morphometry and DNA-cytofluorometry. This development started by day 6 after the infective feed, with passage of mesocyclic midgut trypomastigotes through pr...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099004217

    authors: Van Den Abbeele J,Claes Y,van Bockstaele D,Le Ray D,Coosemans M

    更新日期:1999-05-01 00:00:00

  • Consequence of Hoechst 33342-mediated Leishmania DNA topoisomerase-I inhibition on parasite replication.

    abstract::This study reports that inhibition of Leishmania Topo-I with the minor groove-binding ligands (MGBLs) Hoechst 33342 (Ho342) blocks parasite growth in culture by mechanisms involving DNA breakage. While Ho342 inhibited the replication of several species of Leishmania in a dose- and time-dependent manner, Ho258 was not ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182002002524

    authors: Marquis JF,Drolet M,Olivier M

    更新日期:2003-01-01 00:00:00