A role for antimicrobial peptides in intestinal microsporidiosis.

abstract：:Strongyloides ratti is a parasitic nematode of rats. The host immune response against S. ratti affects the development of its free-living generation, favouring the development of free-living adult males and females at the expense of directly developing, infective 3rd-stage larvae. However, how the host immune response...

journal_title：Parasitology

authors： Crook M,Viney ME

更新日期：2005-09-01 00:00:00

abstract：:The genetic basis of virulence in a line (YM) of Plasmodium yoelii yoelii was investigated in a cross with a mild line (A/C). The blood forms of the virulent line developed extensively in mature erythrocytes of mice, causing death of the host within 7 days; infections with the mild line were normally restricted to ret...

journal_title：Parasitology

authors： Walliker D,Sanderson A,Yoeli M,Hargreaves BJ

更新日期：1976-04-01 00:00:00

abstract：:Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities. Clinical manifestations can range from subclinical infection to very severe systemic disease. Leishmaniosis is categorized as a neg...

journal_title：Parasitology

authors： Hosein S,Blake DP,Solano-Gallego L

更新日期：2017-01-01 00:00:00

abstract：:Adults of the porocephalid pentastomid Porocephalus crotali infect the lung of rattlesnake definitive hosts and larvae develop in rat intermediate hosts. In the latter, nymphs encyst within a variety of tissue sites (commonly abdominal fat bodies and lungs) and each becomes the focus of an eosinophilic granuloma. From...

journal_title：Parasitology

authors： McHardy P,Riley J,Huntley JF

更新日期：1993-01-01 00:00:00

abstract：:Bat flies (Streblidae) are diverse, obligate blood-feeding insects and probably the most conspicuous ectoparasites of bats. They show preferences for specific body regions on their host bat, which are reflected in behavioural characteristics. In this study, we corroborate the categorization of bat flies into three eco...

journal_title：Parasitology

authors： Hiller T,Honner B,Page RA,Tschapka M

更新日期：2018-09-01 00:00:00

abstract：:Part of Robert T. Leiper's (1881-1969) lasting legacy in medical helminthology is grounded on his pioneering work on schistosomiasis (Bilharzia). Having undertaken many expeditions to the tropics, his fascination with parasite life cycles typically allowed him to devise simple preventive measures that curtailed transm...

journal_title：Parasitology

authors： Stothard JR,Kabatereine NB,Archer J,Al-Shehri H,Tchuem-Tchuenté LA,Gyapong M,Bustinduy AL

更新日期：2017-10-01 00:00:00

abstract：:Nematodes are amongst the most successful and abundant organisms on the planet with approximately 30 000 species described, although the actual number of species is estimated to be one million or more. Despite sharing a relatively simple and invariant body plan, there is considerable diversity within the phylum. Nemat...

journal_title：Parasitology

authors： Gillan V,Devaney E

更新日期：2014-08-01 00:00:00

abstract：:This study describes morphological changes during capsule formation of Trichinella spiralis with emphasis on nuclei within the capsule. The nuclei of the pre-existing muscle cell may become hypertrophied or degrade soon after the entrance of newborn larvae. Cytoplasm associated with these hypertrophied nuclei was baso...

journal_title：Parasitology

authors： Matsuo A,Wu Z,Nagano I,Takahashi Y

更新日期：2000-08-01 00:00:00

abstract：:Since 2004 there has been a remarkable increment in our knowledge of the proteins and glycans that reside at, or are released from the surfaces of schistosomes in the mammalian host. Initial characterization of the soluble proteome permits distinctions to be made between the parasite secretome and its necrotome. The p...

journal_title：Parasitology

authors： Wilson RA

更新日期：2012-08-01 00:00:00

abstract：:The transmission from one host to another constitutes a challenging obstacle for parasites and is a key determinant of their fitness. Due to their complex life histories involving several different hosts, the free-living dispersal stages (cercariae) of digenean trematodes show a huge diversity in morphology and behavi...

journal_title：Parasitology

authors： Selbach C,Poulin R

更新日期：2018-09-01 00:00:00

abstract：:Administration of the immunostimulants Corynebacterium parvum, Bacillus Calmette-Guérin (BCG) or Bordetella pertussis prior to, or at the same time as, challenge with Trypanosoma congolense significantly increased survival times in mice, both of trypano-susceptible (A/J) and trypano-resistant (C57Bl) strains. The incr...

journal_title：Parasitology

authors： Murray M,Morrison WI

更新日期：1979-12-01 00:00:00

abstract：:Multiple parasitic infections have become increasingly recognized as a result of improvements in laboratory diagnosis and a growing population of immunocompromised individuals. This review examines the principles of chemotherapy in groupings of multiple infections which are of particular clinical significance. ...

journal_title：Parasitology

authors： Chiodini PL

更新日期：2001-01-01 00:00:00

abstract：:This study assessed the role of historical processes on the geographic isolation, molecular evolution, and morphological diversification of host-parasite populations from the southern Brazilian coast. Adult specimens of Scleromystax barbatus and Scleromystax macropterus were collected from the sub-basin of the Nhundia...

journal_title：Parasitology

authors： Bueno-Silva M,Boeger WA

更新日期：2019-09-01 00:00:00

abstract：:Plant cysteine proteinases (CPs) from Carica papaya kill parasitic and free-living nematodes in vitro by hydrolysis of the worm cuticle, a mechanism that is different to all commercially available synthetic anthelmintics. We have developed a cheap and effective, rapid-throughput Caenorhabditis elegans-based assay for ...

journal_title：Parasitology

authors： Phiri AM,DE Pomerai DI,Buttle DJ,Behnke JM

更新日期：2017-04-01 00:00:00

abstract：:Protective immunity against larval Taenia crassiceps has been shown to rely on T cells; however, the roles of the specific subsets of T cells during infection are not known. To investigate a possible role for gamma delta T cells, this study investigated larval infection in delta-chain knock-out C57BL/6 (deltaKO) and w...

journal_title：Parasitology

authors： Toenjes SA,Spolski RJ,Mooney KA,Kuhn RE

更新日期：1999-10-01 00:00:00

abstract：:As has been shown previously, immunologically intact mice with patent Schistosoma mansoni infections had a significantly lower mean platelet number than intact uninfected mice (P<0.0001). However, platelet numbers in T-cell deprived mice with patent infections were not significantly different from those in uninfected ...

journal_title：Parasitology

authors： Stanley RG,Ngaiza JR,Atieno E,Jell G,Francklow K,Jackson CL,Parry H,Doenhoff MJ

更新日期：2003-03-01 00:00:00

abstract：:Antibodies against variable antigens expressed on the surface of Plasmodium falciparum-infected erythrocytes are believed to be important for protection against malaria. A target for these antibodies is the P. falciparum erythrocyte membrane protein 1, PfEMP1, which is encoded by around 50 var genes and undergoes clon...

journal_title：Parasitology

authors： Giha HA,Staalsoe T,Dodoo D,Elhassan IM,Roper C,Satti GM,Arnot DE,Hviid L,Theander TG

更新日期：1999-07-01 00:00:00

abstract：:The complete nucleotide sequence of the mitochondrial genome was determined for the fish tapeworm Diphyllobothrium latum. This genome is 13,608 bp in length and encodes 12 protein-coding genes (but lacks the atp8), 22 transfer RNA (tRNA) and 2 ribosomal RNA (rRNA) genes, corresponding to the gene complement found thus...

journal_title：Parasitology

authors： Park JK,Kim KH,Kang S,Jeon HK,Kim JH,Littlewood DT,Eom KS

更新日期：2007-05-01 00:00:00

abstract：:Here, the validity of the assumption of concerted evolution of ribosomal regions in larval and adult Cooperia oncophora was assessed. In each of 4 individuals of this parasitic nematode, at least 78% of the sequences comprised different ITS variants. This implies that concerted evolution is not acting, which is corrob...

journal_title：Parasitology

authors： Mes TH,Cornelissen AW

更新日期：2004-08-01 00:00:00

abstract：:Blood examination by microhaematocrit and haemoculture of 459 snakes belonging to 37 species revealed 2.4% trypanosome prevalence in species of Viperidae (Crotalus durissus and Bothrops jararaca) and Colubridae (Pseudoboa nigra). Trypanosome cultures from C. durissus and P. nigra were behaviourally and morphologically...

journal_title：Parasitology

authors： Viola LB,Campaner M,Takata CS,Ferreira RC,Rodrigues AC,Freitas RA,Duarte MR,Grego KF,Barrett TV,Camargo EP,Teixeira MM

更新日期：2008-04-01 00:00:00

abstract：:A specific enzyme-linked immunosorbent assay, based on a 48 kDa metallo-proteinase isolated from the frontal glands of a porocephalid pentastomid (Porocephalus crotali) in rat intermediate hosts, is described. SDS-PAGE analysis of whole nymphal homogenate, followed by Western blotting and probing with immune rat serum...

journal_title：Parasitology

authors： Jones DA,Riley J

更新日期：1991-12-01 00:00:00

abstract：:Fourth-stage larvae of Ascaris suum, recovered from piglets at 11-22 days post-infection (p.i.), were examined by light microscopy for changes in the somatic musculature. During this time the estimated total number of muscle cells in the body increases from approximately 600 to 21 000 cells. This non-eutelic developme...

journal_title：Parasitology

authors： O'Grady RT

更新日期：1984-02-01 00:00:00

abstract：:A new model for the study of granuloma formation in the liver is described. Rats received an injection of 20,000 Schistosoma mansoni eggs in the portal vein and granuloma formation was evaluated at 3, 5 and 7 weeks post-injection. Liver collagen was estimated at the same time and serum procollagen III peptide, a marke...

journal_title：Parasitology

authors： Van Gool J,Van Tiel D,Doenhoff MJ,Van Vugt H

更新日期：1991-02-01 00:00:00

abstract：:The current World Health Organization strategic plan targets the elimination of schistosomiasis as a public health problem by 2025 and accurate diagnostics will play a pivotal role in achieving this goal. DNA-based detection methods provide a viable alternative to some of the commonly used tests, notably microscopy an...

journal_title：Parasitology

authors： Weerakoon KG,Gordon CA,Cai P,Gobert GN,Duke M,Williams GM,McManus DP

更新日期：2017-07-01 00:00:00

abstract：:Uptake of radioactivity labelled purine bases and nucleosides by suspensions of Trypanosoma brucei and Trypanosoma congolense in bicine buffer was determined at 37 degrees C. With T. brucei, the rate of uptake of adenosine was much greater than that of the other compounds tested, the uptake of which decreased in the o...

journal_title：Parasitology

authors： James DM,Born GV

更新日期：1980-10-01 00:00:00

abstract：:The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...

journal_title：Parasitology

authors： Tielens AG,Celik C,Van den Heuvel JM,Elfring RH,Van den Bergh SG

更新日期：1989-02-01 00:00:00

abstract：:The genomes of more than 20 helminths have now been sequenced. Here we perform a meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to address the question of what are the defining characteristics of helminth genomes. We find that parasitic worms lack systems for surface antigenic var...

journal_title：Parasitology

authors： Zarowiecki M,Berriman M

更新日期：2015-02-01 00:00:00

abstract：:A thymine-uracil transport system is present in the plasma membrane brush-border of the tapeworm, Hymenolepis diminuta. The relation between initial uptake and substrate concentration of either thymine or uracil was sigmoidal when 2-14C-labelled substrates were used. In contrast, absorption kinetics of methyl-14C- and...

journal_title：Parasitology

authors： Uglem GL,Dupre RK,Harley JP

更新日期：1983-10-01 00:00:00

abstract：:SUMMARY The necessity to easily establish Histomonas meleagridis cultures has been underlined extensively by many researchers in order to gain more insights in the biology of H. meleagridis. In addition the occurrence of different protozoa in the caeca of birds impedes, however, the isolation and propagation of H. mel...

journal_title：Parasitology

authors： Pham AD,Mast J,DE Gussem JK,McDougald LR,Goddeeris BM

更新日期：2013-09-01 00:00:00

abstract：:A new histozoic species of myxosporean was found to infect the gill filaments, gut, kidney and liver of the freshwater teleost Leporinus friderici, collected from the estuarine region of the Amazon, near the city of Belém, Brazil. The plasmodia show asynchronous development, at any one time composed of mature spores a...

journal_title：Parasitology

authors： Casal G,Matos E,Azevedo C

更新日期：2003-04-01 00:00:00