Uptake of purine bases and nucleosides in African trypanosomes.

abstract：:In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...

journal_title：Parasitology

authors： Tolstrup J,Krause E,Tannich E,Bruchhaus I

更新日期：2007-02-01 00:00:00

abstract：:In situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory...

journal_title：Parasitology

authors： Marsh K

更新日期：1992-01-01 00:00:00

abstract：:The gastrointestinal nematodes (GIN) stand out as an important cause of disease in small ruminant, especially on goat farm. Widespread resistance to synthetic anthelminthics has stimulated the research for alternative strategies of parasite control, including the use of medicinal plants. The present work summarizes th...

journal_title：Parasitology

authors： Oliveira Santos F,Ponce Morais Cerqueira A,Branco A,José Moreira Batatinha M,Borges Botura M

更新日期：2019-09-01 00:00:00

abstract：:Hybridization events between Schistosoma species (Digenea, Platyhelminthes) are reported with increasing frequency, largely due to improved access to molecular tools. Nevertheless, little is known about the distribution and frequency of hybrid schistosomes in nature. Screening for hybrids on a large scale is complicat...

journal_title：Parasitology

authors： Boon NAM,Van Den Broeck F,Faye D,Volckaert FAM,Mboup S,Polman K,Huyse T

更新日期：2018-04-01 00:00:00

abstract：:The complete sequence of the 18S small subunit (SSU) ribosomal DNA of Hammondia hammondi and Sarcocystis mucosa was obtained and compared to SSU rDNA sequences of Neospora caninum, Toxoplasma gondii, Besnoitia besnoiti, 2 species of Frenkelia, 3 species of Isospora, and 13 species of Sarcocystis. Analyses showed that ...

journal_title：Parasitology

authors： Jenkins MC,Ellis JT,Liddell S,Ryce C,Munday BL,Morrison DA,Dubey JP

更新日期：1999-08-01 00:00:00

abstract：:A dipstick dot ELISA for detection of Taenia-specific coproantigens was developed. The test was based on a sandwich ELISA using antibodies raised against adult Taenia solium. Antibodies were absorbed to nitrocellulose paper previously adhered to acetate plastic to form dipsticks. Once blocked with 5% skimmed milk and ...

journal_title：Parasitology

authors： Allan JC,Mencos F,Garcia-Noval J,Sarti E,Flisser A,Wang Y,Liu D,Craig PS

更新日期：1993-07-01 00:00:00

abstract：:In light of the low success rate of target-based genomics and HTS (High Throughput Screening) approaches in anti-infective drug discovery, in silico structure-based drug design (SBDD) is becoming increasingly prominent at the forefront of drug discovery. In silico SBDD can be used to identify novel enzyme inhibitors r...

journal_title：Parasitology

authors： Cunningham F,McPhillie MJ,Johnson AP,Fishwick CW

更新日期：2014-01-01 00:00:00

abstract：:Leishmania braziliensis strain M2903 was adapted for growth and serially maintained as amastigotes at 34 degrees C in modified UM-54 medium, with growth curves exhibiting typical log and stationary phases. In late passages, amastigote growth took place in the absence of supplementary haemin and was unaffected when the...

journal_title：Parasitology

authors： Balanco JM,Pral EM,da Silva S,Bijovsky AT,Mortara RA,Alfieri SC

更新日期：1998-02-01 00:00:00

abstract：:We present observational and experimental evidence that cycles of the Lyme disease spirochaete, Borrelia burgdorferi s.l., can be maintained by sheep in the virtual absence of alternative hosts. A 2-year field study in upland moorland habitats of northwest UK established that sheep feed up to 80% of larval, > 99% of n...

journal_title：Parasitology

authors： Ogden NH,Nuttall PA,Randolph SE

更新日期：1997-12-01 00:00:00

abstract：:Infection of breeding hens with Eimeria maxima induces production of Eimeria-specific IgG antibodies which are transferred to hatchlings via the egg yolk and confer a high degree of maternal immunity against homologous challenge and partial immunity to infection with another important species, Eimeria tenella. As an e...

journal_title：Parasitology

authors： Smith NC,Wallach M,Petracca M,Braun R,Eckert J

更新日期：1994-12-01 00:00:00

abstract：:Within the genus Cryptosporidium 2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mim...

journal_title：Parasitology

authors： Widmer G,Klein P,Bonilla R

更新日期：2007-10-01 00:00:00

abstract：:Parasite-host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused by the microsporidian Nosema bombycis. Such cell surface proteins are considered as promising diagnostic markers and targets for drug development. However, little research has specifically addresse...

journal_title：Parasitology

authors： Zhao W,Hao Y,Wang L,Zhou Z,Li Z

更新日期：2015-06-01 00:00:00

abstract：:Heparin-binding proteins (HBPs) play a key role in Trypanosoma cruzi-host cell interactions. HBPs recognize heparan sulfate (HS) at the host cell surface and are able to induce the cytoadherence and invasion of this parasite. Herein, we analysed the biochemical properties of the HBPs and also evaluated the expression ...

journal_title：Parasitology

authors： Oliveira FO Jr,Alves CR,Silva FS,Côrtes LM,Toma L,Bouças RI,Aguilar T,Nader HB,Pereira MC

更新日期：2013-02-01 00:00:00

abstract：:Genome assemblies can form the basis of comparative analyses fostering insight into the evolutionary genetics of a parasite's pathogenicity, host-pathogen interactions, environmental constraints and invasion biology; however, the length and complexity of many parasite genomes has hampered the development of well-resol...

journal_title：Parasitology

authors： Thompson PC,Zarlenga DS,Liu MY,Rosenthal BM

更新日期：2017-09-01 00:00:00

abstract：:The flatworm nervous system employs a wide repertoire of neuroactive substances, including small chemical messengers, the so called classical transmitters, and several types of neuropeptides. A large body of research accumulated over four decades has provided a wealth of information on the tissue localization and effe...

journal_title：Parasitology

authors： Ribeiro P,El-Shehabi F,Patocka N

更新日期：2005-01-01 00:00:00

abstract：:Toxoplasma gondii is an obligate intracellular protozoan parasite. The objective of the present study was to examine the behaviour of Toxoplasma gondii RH Ankara strain tachyzoites in a cell culture environment. The study represents the first step in determining whether T. gondii RH Ankara strain tachyzoites, grown in...

journal_title：Parasitology

authors： Döskaya M,Degirmenci A,Ciçek C,Ak M,Korkmaz M,Gürüz Y,Uner A

更新日期：2006-03-01 00:00:00

abstract：:We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...

journal_title：Parasitology

authors： Tachibana H,Cheng XJ,Kobayashi S,Okada Y,Itoh J,Takeuchi T

更新日期：2007-12-01 00:00:00

abstract：:Glucose uptake was examined in adult specimens of Proterometra macrostoma (Trematoda: Digenea) recovered from the stomach (endoparasites) and gills (ectoparasites) of longear sunfish, Lepomis megalotis. The endoparasitic forms transported glucose directly through the external body surface by Na+-independent, facilitat...

journal_title：Parasitology

authors： Uglem GL

更新日期：1987-02-01 00:00:00

abstract：:The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

journal_title：Parasitology

authors： Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

更新日期：2012-11-01 00:00:00

abstract：:The free radical nitric oxide (NO) is a neuronal messenger which is synthesized from L-arginine and O2 by nitric oxide synthase (NOS). In the synthesis NO and L-citrulline are produced in a stoichiometric 1:1 relation. The activity of NOS was analysed in homogenates of the rat tapeworm Hymenolepis diminuta by measurin...

journal_title：Parasitology

authors： Terenina NB,Onufriev MV,Gulyaeva NV,Lindholm AM,Gustafsson MK

更新日期：2000-01-01 00:00:00

abstract：:Multiple parasitic infections have become increasingly recognized as a result of improvements in laboratory diagnosis and a growing population of immunocompromised individuals. This review examines the principles of chemotherapy in groupings of multiple infections which are of particular clinical significance. ...

journal_title：Parasitology

authors： Chiodini PL

更新日期：2001-01-01 00:00:00

abstract：:Human strongyloidiasis is a serious disease mostly attributable to Strongyloides stercoralis and to a lesser extent Strongyloides fuelleborni, a parasite mainly of non-human primates. The role of animals as reservoirs of human-infecting Strongyloides is ill-defined, and whether dogs are a source of human infection is ...

journal_title：Parasitology

authors： Barratt JLN,Sapp SGH

更新日期：2020-09-01 00:00:00

abstract：:A procedure is described for the isolation of sub-cellular fractions from bloodstream forms of Trypanosoma brucei. The method leaves intact most of the nuclei, mitochondria and microbodies. All the fractions have been chemically characterized and tested for 10 enzymatic markers. About 5% of total cell protein was isol...

journal_title：Parasitology

authors： Rovis L,Baekkeskov S

更新日期：1980-06-01 00:00:00

abstract：:Immunopathological and ultrastructural studies were carried out on the gut of 30 specimens of powan Coregonus lavaretus (L.) from Lake Piediluco, Italy. The digestive tracts of 10 (33.3%) of the powan were found to harbour an acanthocephalan Dentitruncus truttae (Sinzar 1955). The numerous trunk spines of D. truttae r...

journal_title：Parasitology

authors： Dezfuli BS,Lui A,Giovinazzo G,Boldrini P,Giari L

更新日期：2009-07-01 00:00:00

abstract：:This study reports on morphological variability of Eimeria species, which may be given either by drawings or as quantitative data. The drawings may be used to facilitate identification by eye of 'unknown' Eimeria specimens, whereas quantitative data may serve as a reference set for identification by multivariate stati...

journal_title：Parasitology

authors： Sommer C

更新日期：1998-01-01 00:00:00

abstract：:The protein composition of Schistosoma mansoni was analysed by electrophoresis in polyacrylamide slab gel in the presence of sodium dodecyl sulphate. A high degree of identity existed between protein patterns obtain from immature and adult parasites of the two sexes. Some stage-and sex-specific components were indenti...

journal_title：Parasitology

authors： Ruppel A,Cioli D

更新日期：1977-12-01 00:00:00

abstract：:Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsu...

journal_title：Parasitology

authors： Hartikainen H,Fontes I,Okamura B

更新日期：2013-09-01 00:00:00

abstract：:Costa Rica is near malaria elimination. This achievement has followed shifts in malaria health policy. Here, we evaluate the impacts that different health policies have had on malaria transmission in Costa Rica from 1913 to 2018. We identified regime shifts and used regression models to measure the impact of different...

journal_title：Parasitology

authors： Chaves LF,Ramírez Rojas M,Prado M,Garcés JL,Salas Peraza D,Marín Rodríguez R

更新日期：2020-08-01 00:00:00

abstract：:Pasteuria penetrans is a Gram-positive endospore-producing bacterium that is a parasite of root-knot nematodes. Attachment of endospores to the cuticle of the nematode is the first stage in the infection process. Western blot analysis with monoclonal and polyclonal antibodies that recognize the 30 kDa heparin-binding ...

journal_title：Parasitology

authors： Mohan S,Fould S,Davies KG

更新日期：2001-09-01 00:00:00

abstract：:SIV rats infected with a high dose (50,000 oocysts) of Eimeria nieschulzi displayed clinical symptoms of coccidiosis such as diarrhoea (days 6 and 7 post-primary infection) and weight loss (days 6-8 post-primary infection) and were completely immune to challenge with a similar dose. The ability of rats to produce tumo...

journal_title：Parasitology

authors： Smith NC,Ovington KS,Deplazes P,Eckert J

更新日期：1995-07-01 00:00:00