Abstract:
:Thirty eight years after the successful clinical introduction of antidepressant agents, there has been an important progress in the knowledge and changes in thinking about the role of central serotonergic system in depression and in the mechanism of their therapeutic efficacy. Although it is not clear whether an increase or decrease in serotoninergic function is more important in antidepressant action of agents, there is increasing evidence that almost all antidepressant drugs can induce changes in the sensitivity of somotodendritic 5-HT1A autoreceptors and postsynaptic 5-HT2 receptors in spite of very different pharmacological profiles after a single administration. The question arises as to the causal nature of the relationship between these effects and beneficial clinical action. Further studies are still required to dispel these doubts.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Wielosz Msubject
Has Abstractpub_date
1996-11-01 00:00:00pages
963-72issue
6eissn
0033-2674issn
2391-5854journal_volume
30pub_type
杂志文章,评审abstract:OBJECTIVES:Research results indicate that possibility of building a therapeutic relationship in schizophrenia treatment facilitates better functioning, more effective reduction in psychotic symptoms and fulfillment of patients' personal goals. The aim of the present study was to investigate whether patients systematica...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/31505
更新日期:2015-03-01 00:00:00
abstract::The author presents a literature review of the eventual role of interferon in the etiopathogenesis of schizophrenia. Research material is presented of 20 chronic schizophrenic patients treated with Hu-alpha which seems to substantiate the beneficial effects of this substance in some cases which are resistant to curren...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract:AIM:The evaluation of the activity of selected elements of the immune system in depression. METHOD:Lymphocyte subsets evaluation (CD3+, CD4+, CD8+, CD16+, CD19+, CD4/CD8) was performed in 32 patients with depression (21 women and 11 men in the age from 21 to 66 years) using the flow cytometry method. The cytokine eval...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00
abstract::Premorbid adjustment of 100 hospitalized adolescent patients and its correlation with some clinical variables was assessed and compared with a group of 100 healthy adolescents. The hospitalized group of patients was divided into four diagnostic subgroups according to the diagnostic criteria of ICD 9: psychoses, neuros...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:AIM:The aim of the study was to analyze the occurrence of communication and speech disorders among 8-year-old children in Lódź. The comorbidity of these disorders with mental and somatic disorders was also analysed. We have also studied the correlation between the level of language development and the level of psychic ...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::The family burden (FB) has been defined as a multidimensional impact imposed by an illness on caregivers. FB can be divided into objective (i.e. related to measurable problems) and subjective one (i.e. related to caregivers' emotions arising in response to objective difficulties). FB is known to be related to disturba...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2013-07-01 00:00:00
abstract:AIM:The aim of this case description is the analysis of psychotic symptoms resolution in the context of theory of psychosis as a state of aberrant salience. According to that theory both formation and treatment of psychotic symptoms can be seen in two interconnected dimensions: neurobiological perspective of dopamine h...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract::The purpose of this investigation was to analyze several personality dimensions including several psychopathological symptoms of women experiencing infertility. 70 females experiencing infertility and 50 healthy women were examined using psychological methods: MMPI and the State-Trait Anxiety Inventory by Spielberger,...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:AIM:The objective of the study was to assess the relation between the occurrence of deliberate self-harm (DSH) in young patients during their psychiatric treatment and the presence of specific mental disorders, or the history of suicide attempts, the exposure to abuse and their family situation. METHOD:The studied gro...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract:UNLABELLED:Aggressive and impulsive behaviour are common in Alzheimer's dementia. Therapy of these disorders is an important but difficult practical question. AIM:The purpose of this study was to determine the effect of pharmacological treatment of aggressive behaviour, while taking into account the dynamics of diseas...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract::Prospective longitudinal observation of children socially and emotionally immature and depressive at entering school was carried on till their early adolescence. The study's aim was to describe: 1. childhood depression dynamics, 2. developmental changes in depression, 3. factors related to the depression course, 4. re...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::no summary. ...
journal_title:Psychiatria polska
pub_type: 社论
doi:10.12740/PP/75519
更新日期:2017-08-29 00:00:00
abstract:UNLABELLED:Potentially reversible dementias are rarely detected in out-patient care facilities. Actual reversibility is virtually not known and has been occasionally reported in literature. AIM:To determine the prevalence of potentially reversible dementias among patients seen at the ambulatory care facility and to es...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::There is growing interest in the role of Dehydroepiandrosteron (DHEA) in depression. To evaluate the validity of its administration in depression, the role of DHEA in the mechanism of depression and cardiovascular risk, as so the results of clinical trials must be considered. According to accessible literature, both c...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2009-05-01 00:00:00
abstract::In the article the author would like to draw the readers' attention to one of the central issues of psychoanalysis, i.e. Oedipus complex. In the development of the psychoanalysis the classical conception of Oedipus complex presented by Freud gave rise to a severe criticism both on the part of some psychoanalysts, espe...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:Verification of the level of social support perception and sense of life in patients with anxiety disorder and healthy people; evaluation of the relationship between these variables. METHODS:The Social Support Questionnaire short version (F-SozU K-22) by G. Sommer and T. Fydrich and the Life Attitude Profil...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/81447
更新日期:2019-04-30 00:00:00
abstract:OBJECTIVES:The aim of the study was to assess the supply of selected vitamins and minerals in the daily food rations of patients diagnosed with schizophrenia. METHODS:62 schizophrenia patients (32 women and 30 men aged 21-64, the mean age of women was 41.3 ± 11.2, the mean age of men was 36.1 ± 9.7) took part in the s...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/92280
更新日期:2019-06-30 00:00:00
abstract:UNLABELLED:A pair of auditory stimuli presented in a 0.5 second interval cause a reduction of the P50 auditory evoked potential (P50 AEP) amplitude after the second stimuli in the pair. In some, but not all studies, a clear deficit of such P50 AEP gating was observed in schizophrenic patients. It was present constantly...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Advancement in research on glication process in pathogenesis of AD is presented. Its results may open new, promising possibilities of treatment of neurodegenerative diseases including AD with inhibitors of glication. ...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract::In the review article, the results of studies on regional cerebral blood flow (rCBF) in major depression are presented. Most studies have reported global and regional deficits in cerebral blood flow in major depression as compared to healthy controls. Longitudinal studies show that after recovery from depression an in...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::The author discusses the present state and needs of psychogeriatry in Poland. He considers the situation within the period of 33 years, which, in his opinion, has not been distinctly improved in spite of growth of old age disorders and various psycho-social threats connected with economical difficulties. The author di...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract:AIM:The study was aimed at finding relationships between self-concept, alcohol expectancies and drinking in the group of high school students. It was expected that a higher level of alcohol consumption was related to lower self-concept and positive expectancies concerning alcohol use. METHOD:The group of 229 Polish hi...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:The symptoms of dissociation, depersonalization and derealization are often associated with exposure of patients to mental and physical injuries, usually occurring in childhood. Most of these observations were carried out in populations of patients with various disorders (posttraumatic, conversion-dissocia...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/OnlineFirst/36296
更新日期:2016-01-01 00:00:00
abstract::The authors of this article on the basis "Uber die Klassifikation der Psychosen" analysis present the method of mental disorders' classification proposed by Carl Wernicke in 1899. Wernicke's classification was an alternative for other classification concepts existing in the 19th century. Carl Wernicke as one of the fi...
journal_title:Psychiatria polska
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The paper presents results of the study on the efficacy and tolerability of mirtazapine treatment of patients with depression. The study was open and conducted in three centers. 65 out- and in-patients with diagnosis of depression was included. 50% reduction of the score in the HAM-D scale was obtained in 57%, accordi...
journal_title:Psychiatria polska
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2002-11-01 00:00:00
abstract:UNLABELLED:Central nervous system diseases are connected with the production of an increased amount of reactive oxygen species. Decreased antioxidant activity is considered as one of the causes of tardive dyskinesia (TD) in schizophrenic patients in a prolonged neuroleptic treatment course. AIM:Evaluation of superoxid...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::The impressive developments in research on disturbances of information processing in schizophrenia initiated the effort directed toward correction of these deficits. Studies on cognitive rehabilitation have generated some promising findings regarding the improvements in patients' cognitive and clinical status. However...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:The aim of the study was identification of the barriers making it notably more challenging to access clinics in urban and rural communities. METHODS:The method, which was used in this study adopts the qualitative research perspective. The research tool was an interview with a standardized list of desired in...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/60345
更新日期:2017-02-26 00:00:00
abstract::The paper presents the results of studies on the present state of mental health in persons persecuted for political reasons in Poland in the years 1944-1955. Symptoms of mental disturbances were detected in nearly all examined group. PTSD criteria were applied in the diagnosis. ...
journal_title:Psychiatria polska
pub_type: 历史文章,杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is an autoimmunologic illness, which apart from changes in the skin, the locomotor system and the internal organs, attacks also the nervous system. The paper presents 19 neuropsychiatric symptomic syndromes which after conduction of multidisciplinary, international research were acce...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2000-11-01 00:00:00