Abstract：
:There is growing interest in the role of Dehydroepiandrosteron (DHEA) in depression. To evaluate the validity of its administration in depression, the role of DHEA in the mechanism of depression and cardiovascular risk, as so the results of clinical trials must be considered. According to accessible literature, both concepts of depression--monoaminergic and glucocorticoid--are related. The key role may be played the impairment in regulatory function of monoaminergic, glucocorticoid and GABAergic receptors in the limbic area of the brain, caused by a genetic factor or acquired by stress. Consequently even weak stimulation could lead to inefficiency of the Limbic- hypothalamic-pituitary-adrenal (LHPA) homeostasis, with overproduction of cortisol. The excess of cortisol is facilitating the development of depression by damaging the limbic, especially hippocampal neurons. Furthermore, the cortisol is increasing cardiovascular risk by its atherogenic properties. The DHEA, because of its antiglucocorticoid activity is supposed to be a protective factor against depression and cardiovascular risk. Positive effects of administration of DHEA in depression were observed in clinical trials. However the results of estimation of DHEA and SDHEA in the blood of depressed patients were inconsistent. In animals, administration of high doses of DHEA was decreasing the experimental atherogenesis. However the investigation in numbered human populations showed correlation of increased level of DHEA with a decreased risk of cardiovascular disorder in men--but not in women. Further research on relation between depression, DHEA and cardiovascular risk, with special concern upon the differences in men and women is needed.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Załuska M,Janota Bsubject
Has Abstractpub_date
2009-05-01 00:00:00pages
263-74issue
3eissn
0033-2674issn
2391-5854journal_volume
43pub_type
杂志文章,评审abstract：:Mild cognitive impairment (MCI) is present in on average one-fourth of Parkinson's disease (PD) patients with no dementia diagnosis. Only recently has PD-MCI been treated as a new diagnostic entity. In 2012, unified criteria were adopted which allow both diagnosing MCI in Parkinson's disease (PD-MCI) and further class...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:The authors of this article on the basis "Uber die Klassifikation der Psychosen" analysis present the method of mental disorders' classification proposed by Carl Wernicke in 1899. Wernicke's classification was an alternative for other classification concepts existing in the 19th century. Carl Wernicke as one of the fi...
journal_title：Psychiatria polska
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：AIM:Construction of a questionnaire describing personality traits connected to the occurrence and persistence of neurotic disorders. METHOD:Responses of 794 patients (before treatment) and 520 persons from the control group on items of the constructed personality questionnaire and the symptom checklist "0". Analyses o...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：:Plasma cortisol level was measured 7 times between 3 and 5 pm in 34 inpatients with major depression and 25 controls. 1 mg of dexamethasone per os was administrated the day before a 11 pm. The maximum, minimum, mean and range of cortisol concentration were calculated. All these parameters were statistically significan...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：:2008 brings the 70th anniversary of the first electroconvulsive treatment, which was applied in a Psychiatric Clinic of Rome and introduced a new physical therapy to the clinical practice. The electroconvulsive therapy (ECT)--remains as the only method from the earlier therapies practised in the era preceding modem ph...
journal_title：Psychiatria polska
pub_type： 历史文章,杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:This article discusses biochemical changes of ethyl alcohol in human organism, concentrating especially on the negative influence on the metabolism of liver. The authors describe the process of oxidation of alcohol with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) and emphasize the role of ADH i ALDH ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVES:The objective of the study was to show the correlation between the feelings of stigmatization and depressive symptoms in psoriasis patients. The study has considered severity of feelings of stigmatization and depressive symptoms, as well as factors such as gender and skin lesions visibility. METHODS:The stu...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/68848
更新日期：2017-12-30 00:00:00
abstract：AIM:The aim of the present investigations was qualification of influence of loss of near and dear persons on cognitive functions in persons with Alzheimer's disease. METHOD:The initial population consisted of all the people who in the period from 1/02 to 30/10/2000 were treated at one of the following psychiatric trea...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：:Five-year observation performed on 204 persons indicates that depressive symptoms very often appear in the preclinical period of dementia of the Alzheimer type. ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:Anorexia nervosa (AN) most often has its onset in adolescence, which is a crucial period to achieve peak bone mass. The hormonal abnormalities (hypoestrogenism, hypercortisolism, decreased secretion of dehydroepiandrosterone, testosterone, insulin-like growth factor) and malnutrition are associated with profound bone ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/59289
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:Verification of the level of social support perception and sense of life in patients with anxiety disorder and healthy people; evaluation of the relationship between these variables. METHODS:The Social Support Questionnaire short version (F-SozU K-22) by G. Sommer and T. Fydrich and the Life Attitude Profil...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/81447
更新日期：2019-04-30 00:00:00
abstract：OBJECTIVES:Having the opportunity to work has been found meaningful for individuals suffering from severe mental illness, in order to boost their self-esteem, provide a sense of control over their lives and of belonging to a community. There are no studies in Polish literature on the process of recovery from schizophre...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/44238
更新日期：2016-01-01 00:00:00
abstract：:The aim of this paper is to discuss the impact and significance of religious beliefs on the dissociation and somatization symptoms presented by a hospitalised female patient. A 16-year-old girl was hospitalised at the Developmental Age Psychiatry and Psychotherapy Clinical Ward (The Clinical PiPWR Ward) for observatio...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Caregiver burden was evaluated among family members of 90 schizophrenic patients from hospital psychiatric ward, day hospital or from community psychiatry unit. Psychopathology was evaluated with the use of PANSS while family burden with the use of Tessler's scale which allowed to differentiate between objective and s...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:The article summarizes briefly the most important directions of research in the quality of life (QOL) of schizophrenic patients. Results gained by cited authors seem to confirm that the QOL of these patients is lower in comparison with normal population. Researchers look for factors that would be able to rise the subj...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1996-05-01 00:00:00
abstract：:The aim of the work was to establish the usefulness of alcoholism scales enclosed in MMPI for the evaluation of risk of alcohol dependence among college students. The results of 1255 college students from different schools and various years of studium were reviewed. The risk of alcohol dependence was established by an...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVES:The aim of the study was identification of the barriers making it notably more challenging to access clinics in urban and rural communities. METHODS:The method, which was used in this study adopts the qualitative research perspective. The research tool was an interview with a standardized list of desired in...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/60345
更新日期：2017-02-26 00:00:00
abstract：BACKGROUND:We analyzed metabolic profile of patients with cognitive dysfunctions by means of levels of lipoproteins, glycaemia and hypertension. RESEARCH DESIGN AND METHODS:In naturalistic, open manner, we studied 100 persons--44 without cognitive dysfunctions, 17 with MCI and 39 with dementia. Patients were grouped a...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2013-11-01 00:00:00
abstract：:Second generation antipsychotics share some similarities but display also differences in their action. The pharmacological profile as well as the clinical efficacy and tolerability of these drugs currently on the market in Poland have been described. The analysis of their properties reveals distinct differences betwee...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：:The cloze procedure was used to examine: predictability in speech samples from schizophrenics and their mothers as well as their ability to gain from the redundancy of language. Schizophrenic patients were found to be less predictable than normals, both schizophrenics and their mothers were less able to make use of th...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：AIM:The study was aimed at finding relationships between self-concept, alcohol expectancies and drinking in the group of high school students. It was expected that a higher level of alcohol consumption was related to lower self-concept and positive expectancies concerning alcohol use. METHOD:The group of 229 Polish hi...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-05-01 00:00:00
abstract：:Premorbid adjustment of 100 hospitalized adolescent patients and its correlation with some clinical variables was assessed and compared with a group of 100 healthy adolescents. The hospitalized group of patients was divided into four diagnostic subgroups according to the diagnostic criteria of ICD 9: psychoses, neuros...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:The antidepressive effect of Hydiphen was evaluated and compared with imipramine in patients with endogenous depression. The Hydiphen group consisted of 23, and imipramine group of 22 subjects. The evaluation was made using psychometric scales, orthostatic test, ecg, and laboratory tests before treatment as well as du...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:In the inauguration speech of the Congress stages of the path taken by the Polish Psychiatric Society were described in short: 1--The period from its establishment till 1939; 2--Tragic years of the war, 1939-1945, with extermination of ca. 20,000 patients and many psychiatrists; 3--Reconstruction after the war, accomp...
journal_title：Psychiatria polska
pub_type： 历史文章,杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVES:The aim of paper was to explore the attitudes of Polish psychology students towards lesbian mothers whose children undergo psychological intervention, in an imaginary situation of providing professional support to the child. The authors found 3 types of psychologist behaviour: contact omission (withdrawal fr...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：:The theme of the article is a 68-year old patient whose case was diagnosed as organic brain disease complicated by musical hallucinosis. The patient was admitted to a mental hospital, several times, as suffering from psychic disturbances of the auditory hallucinosis type whose dominant symptom are musical hallucinatio...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVE:This study examined 1H MRS detected metabolite levels (in left frontal, temporal lobes and thalamus) and clinical and cognitive features of patients with first-episode and chronic schizophrenia. METHOD:We studied 31 first-episode patients (group 1) and 17 chronic patients (group 2) with ICD-10 diagnosis of s...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:The authors discuss the concept of systemic diagnosis and its logical and scientific validity. A diagnosis is the result of the "diagnostic process", with the presence of the acting object (the person making the diagnosis) and the subject (the individual or group patient, such as family), between whom there is a skew ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:to assess the prevalence of obsessive-compulsive disorder (OCD) or OC symptoms in patients with anorexia nervosa (AN) and to find a possible relationship between the presence of OC symptoms and the course of AN. METHOD:137 adolescent female patients with AN, aged 14.8 +/- 1.8 years, completed the Polish vers...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：AIM:This study investigated the relation between problem-solving strategies in the marital conflict and marital satisfaction. METHOD:Four problem-solving strategies (Dialogue, Loyalty, Escalation of conflict and Withdrawal) were measured by the Problem-Solving Strategies Inventory, in two versions: self-report and rep...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
