Abstract：
AIM:The evaluation of the activity of selected elements of the immune system in depression. METHOD:Lymphocyte subsets evaluation (CD3+, CD4+, CD8+, CD16+, CD19+, CD4/CD8) was performed in 32 patients with depression (21 women and 11 men in the age from 21 to 66 years) using the flow cytometry method. The cytokine evaluation (sIL-2R, IL-4, IL-6) was performed in 39 patients with depression (23 women and 16 men in the age from 21 to 66 years) using the ELISA method. The evaluation was also performed in 32 healthy controls (16 women and 16 men in the age from 23 to 61). RESULTS:Statistically significant differences were observed in lymphocyte subsets between depressed patients and healthy controls (increase of CD16+, CD4/CD8, decrease of CD3+, CD8+ in depression, decrease of CD3+, CD8+, CD19+ and increase of CD4/CD8 in remission). There were no significant differences between depressed men and women in the above parameters during exacerbation and remission of depression. Statistically significant differences were observed in cytokine concentration between patients during acute episodes of depressions and healthy controls (higher sIL-2R level, lower IL-4 level), but not in remission. Also, there were no significant differences between men and women in the above parameters during exacerbation and remission of the illness. No correlation was found between age and immunological indicators. CONCLUSION:The results obtained confirm changes of immune system activity in depression, including both activation and supression in the same time. It may suggest an immunological inbalance during depression.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Wójciak P,Sobieska M,Kostrzewa A,Rybakowski Jsubject
Has Abstractpub_date
2007-09-01 00:00:00pages
637-49issue
5eissn
0033-2674issn
2391-5854journal_volume
41pub_type
杂志文章abstract：:A polish translation and the description of the clinical use of the novel screening tool in Alzheimer's disease, a "7 Minute Screen", is presented. ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:The evaluation of neurophysiological markers during imipramine treatment of 60 patients with endogenous depression was made. These markers were evaluated in 2 groups of patients: with cardio-vascular, and with brain circulation disturbances; both groups equal 30 subjects. During thymoleptic treatment of patients with ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:no summary. ...
journal_title：Psychiatria polska
pub_type： 社论
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2005-03-01 00:00:00
abstract：AIMS:To validate the Polish version of the Athens Insomnia Scale (AIS), the instrument designed for quantitative measurement of the severity of insomnia based on the ICD-10 criteria. METHOD:The AIS was administered to 356 subjects: 160 patients from the sleep clinic presenting with ICD-10 non-organic insomnia (90f; me...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/32500
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journal_title：Psychiatria polska
pub_type： 杂志文章
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/59289
更新日期：2016-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2006-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 信件
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更新日期：2015-05-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2013-07-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
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pub_type： 杂志文章
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journal_title：Psychiatria polska
pub_type： 杂志文章
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
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更新日期：1996-05-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
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journal_title：Psychiatria polska
pub_type： 杂志文章
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-01-01 00:00:00
