Abstract：
:Treatment for depression is not effective in all patients and it is therefore important to identify factors that can be used to tailor treatments. One potential factor is insomnia. Several repetitive transcranial magnetic stimulation (rTMS) studies have reported on this symptom, however, they did not take into account the presence of hypersomnia or that insomnia was related to their outcome measure. Our aim was to investigate whether baseline sleep disruption was related to rTMS treatment response. We pooled data from four clinical trials using rTMS to treat depression, including 139 subjects in data analysis. Insomnia was measured using the Hamilton Depression Rating Scale (HamD) sleep questions and hypersomnia from the Beck Depression Inventory (BDI). To reduce the possible impact of insomnia on our treatment response outcome we created an adjusted HamD score which omitted sleep items. Sleep disturbances were common in our study: 66% had insomnia and 38% hypersomnia. Using regression analysis with our adjusted HamD score we found no relation between baseline insomnia or hypersomnia and rTMS treatment response. Our data are consistent with previous studies; however, this is the first rTMS study to our knowledge that has attempted to dissociate baseline insomnia from the HamD outcome measure and to report no relationship between hypersomnia and rTMS outcome.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Lowe A,Rajaratnam SM,Hoy K,Taffe J,Fitzgerald PBdoi
10.1016/j.psychres.2013.04.028subject
Has Abstractpub_date
2013-11-30 00:00:00pages
121-6issue
1eissn
0165-1781issn
1872-7123pii
S0165-1781(13)00238-2journal_volume
210pub_type
临床试验,杂志文章abstract：:The application of psychometric procedures to a normal population sample to detect individuals with increased liability for schizophrenia is a useful methodological adjunct to the traditional genetic high-risk strategy. A necessary and reasonable step in the process of establishing the utility of a viable psychometric...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(90)90041-3
更新日期：1990-09-01 00:00:00
abstract：:Following a drug-free placebo period lasting at least 1 week, 10 female and 11 male newly hospitalized schizophrenic patients received chlorpromazine (CPZ) 200 mg/day for 1 week and 400 mg/day the following week. Serum CPZ equivalent (CPZ-E) levels were measured at the end of each week of CPZ treatment with a radiorec...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90001-x
更新日期：1983-08-01 00:00:00
abstract：:Firefighters represent a unique, vulnerable population at high risk for alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) symptomatology due to the high rates of occupational exposure to traumatic events. To inform specialized alcohol use interventions for firefighters, it is important to understand ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112633
更新日期：2019-12-01 00:00:00
abstract：:This study compared basal concentrations of plasma beta-endorphin/beta-lipotropin-like immunoreactivity and dexamethasone suppression of cortisol in seven chronic pain patients, seven psychiatric disorder patients, and seven normal volunteers. Pain patients and psychiatric patients showed significantly higher basal co...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90005-7
更新日期：1983-08-01 00:00:00
abstract：:This report explores the relationship between age of first onset of major depression and other demographic and clinical features in the first 1500 patients entering the Sequenced Treatment Alternative to Relieving Depression (STAR*D) study. Outpatients, 18-75 years of age, with nonpsychotic major depressive disorder (...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.07.004
更新日期：2004-12-15 00:00:00
abstract：:Depression is associated with three distinct alterations in memory functioning: mood-congruent recall, over-generality, and intrusive memories. These concern the autobiographical memory system, yet no previous studies have examined the neural correlates of autobiographical memory function in depression. In the present...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2011.08.008
更新日期：2012-02-28 00:00:00
abstract：:Posttraumatic stress disorder (PTSD) research has focused largely on fear processing. However, interpersonal trauma exposure can also impact interpersonal functioning and the perception of the trustworthiness of others. The present study examined facial perceptions of fearfulness and trustworthiness in individuals wit...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.01.056
更新日期：2016-03-30 00:00:00
abstract：:The objective of this paper was to examine the efficacy of mindfulness-based cognitive therapy (MBCT) in decreasing depressive symptoms and intellectual disabilities (ID) among individuals with depression in Nigeria. In this randomized controlled trial, 101 participants with depression and ID, aged 18-60 years, who ob...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113680
更新日期：2020-12-24 00:00:00
abstract：:Before and after a double-blind trial of haloperidol vs. mesoridazine, 24 hospitalized schizophrenics performed visual perception tasks designed to assess function of the cerebral hemispheres. Tasks involved identifying as "same" or "different" two images (either letters, digits, or unfamiliar shapes) projected tachis...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/0165-1781(79)90014-3
更新日期：1979-12-01 00:00:00
abstract：:This study measured changes in regional cerebral blood flow (rCBF) during the complex cognitive task of meditation using single photon emission computed tomography. Eight experienced Tibetan Buddhist meditators were injected at baseline with 7 mCi HMPAO and scanned 20 min later for 45 min. The subjects then meditated ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(01)00074-9
更新日期：2001-04-10 00:00:00
abstract：:The medial temporal cortex (MTC) has been implicated in the pathogenesis of pediatric major depressive disorder (MDD). Eleven MDD case-control pairs underwent proton magnetic resonance spectroscopic imaging. N-acetyl-aspartate was lower in the left MTC (27%) in MDD patients versus controls. Lower N-acetyl-aspartate co...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2007.12.022
更新日期：2008-10-30 00:00:00
abstract：:Our study aimed to examine the interplay between clinical and social predictors of future suicide attempt and the transition from suicidal ideation to suicide attempt in depressive disorders. Sixty-six Malaysian inpatients with a depressive disorder were assessed at index admission and within 1 year for suicide attemp...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.08.055
更新日期：2014-12-30 00:00:00
abstract：:The role of stressful precipitating events has long been recognized in the genesis of obsessive-compulsive disorder (OCD). Posttraumatic stress disorder (PTSD) also necessitates the experience of a traumatic event (PTSD criterion A). Research has demonstrated a high degree of comorbidity between these two conditions. ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112508
更新日期：2019-10-01 00:00:00
abstract：:Recent investigations suggest that serotonergic mechanisms modulate dimensions of personality, in particular decreases in Anger-Hostility and increases in Affiliation. None of these studies, however, demonstrated a specific serotonergic effect on personality, as other neurotransmitter systems have not been assessed fo...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/s0165-1781(99)00041-4
更新日期：1999-06-30 00:00:00
abstract：:The aim of this paper is to extensively review the current literature available on N-acetylcysteine (NAC) treatment for cocaine dependence (clinical and experimental studies). We screened all articles published before February 2016 reporting on the use of NAC as a pharmacological intervention for cocaine dependence or...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2017.02.024
更新日期：2017-05-01 00:00:00
abstract：:This study explores the psychometric characteristics of the Behavior Problems Inventory (BPI), an instrument for routine clinical assessment of behavior problems in outpatients with psychosis based on information provided by key family informants. Six hundred and twenty-one patients diagnosed with psychosis and bipola...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.03.051
更新日期：2018-12-01 00:00:00
abstract：:Cholesterol, sodium, potassium, and serum glucose were examined to determine if they could predict status on the dexamethasone suppression test (DST) in 59 depressed prepubertal psychiatric inpatients and 21 nondepressed psychiatric inpatients. Multivariate analyses found that none of these variables, alone or combine...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(89)90036-x
更新日期：1989-08-01 00:00:00
abstract：:Anhedonia has traditionally been considered a characteristic feature of schizophrenia, but the true nature of this deficit remains elusive. This study sought to investigate consummatory and anticipatory pleasure as it relates to motivation deficits. Eighty-four outpatients with schizophrenia and 81 healthy controls we...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.04.040
更新日期：2017-08-01 00:00:00
abstract：:The current study aims to further evaluate the psychometric properties of the Maryland Assessment of Recovery in Serious Mental Illness (MARS), a relatively new instrument designed to assess personal recovery status in individuals with serious mental illness. Two hundred and fifty individuals with serious mental illne...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.03.031
更新日期：2016-05-30 00:00:00
abstract：:A significant association between anxiety and depersonalization has been found in healthy controls and psychiatric patients irrespective of underlying conditions. Although patients with depersonalization disorder (DPD) often have a history of severe anxiety symptoms, clinical observations suggest that the relation bet...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.12.017
更新日期：2012-05-15 00:00:00
abstract：:Depressive episodes are a common and potentially severe occurrence in schizophrenia but are poorly recognised by psychiatrists. Coherent diagnostic criteria are necessary to improve diagnosis and treatment of these conditions. To evaluate the usefulness of the ICD-10 category of post-schizophrenic depression (PSD) and...
journal_title：Psychiatry research
pub_type：
doi：10.1016/s0165-1781(02)00298-6
更新日期：2003-01-25 00:00:00
abstract：:If Borderline Personality Disorder (BPD) is characterized by an underlying emotional sensitivity, individuals with this disorder would be expected to demonstrate accurate identification of emotional expressions at earlier stages of expression (i.e., lower thresholds of facial expressivity across all emotional valences...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.12.019
更新日期：2011-05-15 00:00:00
abstract：:The present examination raises the question whether attrition in a longitudinal study leads to biased findings. The Zurich Adolescent Psychology and Psychopathology Study (ZAPPS) originated in 1994 by following a sample of 1239 adolescents with follow-ups after three, six, and 22 years. The study collected data on lif...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112685
更新日期：2020-02-01 00:00:00
abstract：:Social cognitive deficits in schizophrenia are well documented and related to functional outcome. Current social cognition measures are often not psychometrically validated, too heterogeneous for standardization, and focus principally on one domain of social cognition rather than the simultaneous activation of multipl...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.03.014
更新日期：2014-07-30 00:00:00
abstract：:The jumping to conclusions bias (JTC), in which some people gather less information than others before making a decision, has been linked to delusions in psychosis. JTC is usually identified via the beads task, in which a sequence of beads (the "target" sequence) is used to measure the amount of evidence participants ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.043
更新日期：2018-07-01 00:00:00
abstract：:Our main purpose was to investigate how smoking and nicotine interacted with specific aspects of cognitive functioning. The research was conducted in two parts: (i) an investigation of cognition in heavy smokers and healthy nonsmokers, and (ii) an investigation of cognition in healthy nonsmokers enrolled in a clinical...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113357
更新日期：2020-11-01 00:00:00
abstract：:Plasma free homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) were measured before drug treatment in 29 patients diagnosed as having major depression with melancholia and in 18 control subjects. Plasma HVA was significantly elevated in the total group of female melancholic patients when compared with ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(85)90033-2
更新日期：1985-05-01 00:00:00
abstract：:Religion and/or spirituality (R/S) can play a vital, multifaceted role in mental health. While beliefs about God represent the core of many psychiatric patients' meaning systems, research has not examined how internalized images of the divine might contribute to outcomes in treatment programs/settings that emphasize m...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.05.003
更新日期：2017-08-01 00:00:00
abstract：:The current studies examined the role of 'not just right' experiences (NJREs) and incompleteness (INC) in body dysmorphic disorder (BDD). In Study 1, a clinical BDD sample endorsed more severe NJREs than healthy controls, when controlling co-occurring symptoms of depression and anxiety. In Study 2, INC predicted react...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.11.038
更新日期：2017-01-01 00:00:00
abstract：:As the serotonin transporter gene (SLC6A4 or 5-HTT) is a key regulator of central serotonergic activity, several association studies between Antisocial Personality Disorder (APD) and the SLC6A4 polymorphisms have been conducted in the last decade. In the present study, the role of both 5-HTTLPR and 5-HTTVNTR polymorph...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.12.018
更新日期：2010-05-15 00:00:00
