Hemispheric dysfunction in schizophrenia: assessment by visual perception tasks.

Abstract:

:Before and after a double-blind trial of haloperidol vs. mesoridazine, 24 hospitalized schizophrenics performed visual perception tasks designed to assess function of the cerebral hemispheres. Tasks involved identifying as "same" or "different" two images (either letters, digits, or unfamiliar shapes) projected tachistoscopically to the right or left visual field or to both together. Multivariate analysis of variance related response latency and accuracy to task type, hemisphere stimulated, and pre- vs. posttreatment testing. Both before and after treatment, subjects responded most slowly and least accurately to letter-matching. Bilateral presentation of stimuli resulted in faster and more accurate responses, except on shape-matching. Neuroleptic treatment improved speed and accuracy overall, though not under certain task conditions. Results accorded more with an impairment in verbal processing and interhemispheric coordination than with a specific left-hemispheric deficit in schizophrenia.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Eaton EM,Busk J,Maloney MP,Sloane RB,Whipple K,White K

doi

10.1016/0165-1781(79)90014-3

subject

Has Abstract

pub_date

1979-12-01 00:00:00

pages

325-32

issue

3

eissn

0165-1781

issn

1872-7123

pii

0165-1781(79)90014-3

journal_volume

1

pub_type

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