Abstract:
:Before and after a double-blind trial of haloperidol vs. mesoridazine, 24 hospitalized schizophrenics performed visual perception tasks designed to assess function of the cerebral hemispheres. Tasks involved identifying as "same" or "different" two images (either letters, digits, or unfamiliar shapes) projected tachistoscopically to the right or left visual field or to both together. Multivariate analysis of variance related response latency and accuracy to task type, hemisphere stimulated, and pre- vs. posttreatment testing. Both before and after treatment, subjects responded most slowly and least accurately to letter-matching. Bilateral presentation of stimuli resulted in faster and more accurate responses, except on shape-matching. Neuroleptic treatment improved speed and accuracy overall, though not under certain task conditions. Results accorded more with an impairment in verbal processing and interhemispheric coordination than with a specific left-hemispheric deficit in schizophrenia.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Eaton EM,Busk J,Maloney MP,Sloane RB,Whipple K,White Kdoi
10.1016/0165-1781(79)90014-3subject
Has Abstractpub_date
1979-12-01 00:00:00pages
325-32issue
3eissn
0165-1781issn
1872-7123pii
0165-1781(79)90014-3journal_volume
1pub_type
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