Biological and clinical validation of atypical depression.

Abstract:

:Depressed patients with (a) mood reactivity alone (MR group), (b) mood reactivity plus one or more associated features (atypical depression, AD group), and (c) patients with neither mood reactivity nor atypical depression (non-MR/AD group) were compared on their cortisol response to 75 mg of desipramine (DMI), a relatively selective norepinephrine reuptake inhibitor. AD patients exhibited a significantly higher cortisol response to DMI compared with MR and non-MR/AD patients, suggesting that atypical depression may be associated with a less impaired norepinephrine system. MR and non-MR/AD patients did not differ, suggesting that mood reactivity alone is not associated with the biological profile observed in atypical depression. Results indicate that while mood reactivity may be necessary for the diagnosis of atypical depression, the additional presence of at least one associated symptom is required for a distinct biological profile. Our findings provide further biological validation of the concept of atypical depression.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

McGinn LK,Asnis GM,Rubinson E

doi

10.1016/0165-1781(96)02781-3

subject

Has Abstract

pub_date

1996-03-29 00:00:00

pages

191-8

issue

2-3

eissn

0165-1781

issn

1872-7123

pii

0165-1781(96)02781-3

journal_volume

60

pub_type

杂志文章
  • Decreased serum levels of adiponectin in adult attention deficit hyperactivity disorder.

    abstract::The main aim of this study was to investigate serum levels of adiponectin in adult patients with attention deficit hyperactivity disorder (ADHD). The second objective was to examine the effects of rare missense mutations in T-cadherin, an adiponectin receptor encoded by the ADHD candidate gene CDH13, on serum adiponec...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.01.025

    authors: Mavroconstanti T,Halmøy A,Haavik J

    更新日期:2014-04-30 00:00:00

  • Determining populations at risk for developing anorexia nervosa based on selection of college major.

    abstract::The prevalence of symptoms of anorexia nervosa among students majoring in the areas of dance, drama, physical education, and English was determined by using the Eating Attitudes Test (EAT). It was hypothesized that female students who might be prone to develop anorexia nervosa as indicated by anorectic symptoms on the...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(82)90052-x

    authors: Joseph A,Wood IK,Goldberg SC

    更新日期:1982-08-01 00:00:00

  • Association between cognitive performance and striatal dopamine binding is higher in timing and motor tasks in patients with schizophrenia.

    abstract::The basal ganglia have received increasing attention with regard to their role in time pacing, motor function and other components of cognition. The aim of this study was to test whether the finer the motor activity and/or time perception performance were, the higher the striatal dopamine D(2) binding would be. Single...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2003.07.002

    authors: Yang YK,Yeh TL,Chiu NT,Lee IH,Chen PS,Lee LC,Jeffries KJ

    更新日期:2004-09-15 00:00:00

  • Danger in danger: Interpersonal violence during COVID-19 quarantine.

    abstract:BACKGROUND:Intimate partner violence (IPV) is defined as physical or sexual violence, emotional abuse and stalking. It is typically experienced by women but can also be experienced by men. During quarantine due to the COVID-19, home risks to become a very dangerous place for victims of domestic violence. METHOD:Very r...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113046

    authors: Mazza M,Marano G,Lai C,Janiri L,Sani G

    更新日期:2020-04-30 00:00:00

  • The effects of aerobic exercise on cognition in schizophrenia: A 3-month follow-up study.

    abstract::Aerobic exercise (AE) has been shown to improve cognition in patients with schizophrenia. However, it remains unclear whether these exercise-induced cognitive benefits persist beyond the training period. Accordingly, the present study sought to examine the immediate and maintenance effects of AE on a wide range of cog...

    journal_title:Psychiatry research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.psychres.2016.08.011

    authors: Su CY,Wang PW,Lin YJ,Tang TC,Liu MF,Chen MD

    更新日期:2016-10-30 00:00:00

  • Assessment of tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption.

    abstract::This prospective cross-sectional study aimed to investigate the potential association between primary-adult lactose malabsorption, fructose malabsorption, tryptophan (TRP) metabolism and the presence of depressive signs. Overall 251 patients, who were referred for lactase gene C/T-13910 polymorphism genotyping and fru...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.09.049

    authors: Enko D,Wagner H,Kriegshäuser G,Brandmayr W,Halwachs-Baumann G,Schnedl WJ,Zelzer S,Mangge H,Meinitzer A

    更新日期:2018-04-01 00:00:00

  • Aggression and delinquent behavior in a large representative sample of high school students: Cannabis use and victimization as key discriminating factors.

    abstract:PURPOSE:Since conduct problems (CP) vary distinctly across youths, better subtyping CP may be an important vehicle to study specific risk factors associated to differential patterns of CP. In a sample of 63,196 adolescents, we employed a two-step method to the identify such CP patterns and to help classify youths based...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113640

    authors: Dugré JR,Potvin S,Dellazizzo L,Dumais A

    更新日期:2020-12-11 00:00:00

  • PTSD and obesity in younger and older veterans: Results from the mind your heart study.

    abstract::Posttraumatic stress disorder (PTSD) is increasingly recognized as a relatively common condition that is associated with poor health, including obesity. With a sizable proportion of the population approaching older adulthood, it is important to understand PTSD-health associations in the context of age. Participants we...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.07.044

    authors: Smith BN,Tyzik AL,Neylan TC,Cohen BE

    更新日期:2015-10-30 00:00:00

  • Tourette's syndrome, trichotillomania, and obsessive-compulsive disorder: how closely are they related?

    abstract::The question of whether Tourette's syndrome (TS) and trichotillomania (TTM) are best conceptualized as obsessive-compulsive spectrum disorders was raised by family studies demonstrating a close relationship between TS and obsessive-compulsive disorder (OCD), and by psychopharmacological research indicating that both T...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2008.06.008

    authors: Ferrão YA,Miguel E,Stein DJ

    更新日期:2009-11-30 00:00:00

  • The NimStim set of facial expressions: judgments from untrained research participants.

    abstract::A set of face stimuli called the NimStim Set of Facial Expressions is described. The goal in creating this set was to provide facial expressions that untrained individuals, characteristic of research participants, would recognize. This set is large in number, multiracial, and available to the scientific community onli...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2008.05.006

    authors: Tottenham N,Tanaka JW,Leon AC,McCarry T,Nurse M,Hare TA,Marcus DJ,Westerlund A,Casey BJ,Nelson C

    更新日期:2009-08-15 00:00:00

  • Higher blood MLL1 mRNA and BDNF promoter IV on histone H3K4me3 levels in patients with schizophrenia.

    abstract::We investigated the blood levels of mixed-lineage leukemia 1 (MLL1) mRNA and BDNF (brain derived neurotrophic factor) exon IV promoter on histone Histone 3 lysine 4 trimethylation (H3K4me3) in peripheral blood of patients with schizophrenia and controls. Over one year, 36 patients with schizophrenia and 32 controls we...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.06.010

    authors: Huang TL,Lin CC,Chen RF,Lee CT

    更新日期:2016-09-30 00:00:00

  • Neuropsychological deficit in schizophrenic subtypes: paranoid, nonparanoid, and schizoaffective subgroups.

    abstract::Schizophrenic patients were carefully diagnosed and screened for a history of neurological disorders. Diagnosis and subtyping was based on DSM-III-R criteria, using the Structured Clinical Interview for DSM-III-R, which was administered by trained interviewers and confirmed by a research psychiatrist. The schizophreni...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(90)90104-d

    authors: Bornstein RA,Nasrallah HA,Olson SC,Coffman JA,Torello M,Schwarzkopf SB

    更新日期:1990-01-01 00:00:00

  • Proton magnetic resonance spectroscopy of late-life major depressive disorder.

    abstract::The primary goal of this study was to examine the biochemical abnormalities of late-life major depression by using 3-tesla (3-T) proton magnetic resonance spectroscopy ((1)H-MRS). The antidepressant effects on the biochemical abnormalities were investigated as well. Study participants were 27 elderly patients with maj...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2009.01.003

    authors: Chen CS,Chiang IC,Li CW,Lin WC,Lu CY,Hsieh TJ,Liu GC,Lin HF,Kuo YT

    更新日期:2009-06-30 00:00:00

  • Post-traumatic psychological changes among survivors of the Lushan earthquake living in the most affected areas.

    abstract::The primary objective of our study was to investigate both the negative and positive psychological changes following the Lushan earthquake, and to explore the factors associated with psychological changes. Multi-stage random sampling was used to select respondents from Lushan County, Sichuan Province, China. A simplif...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2014.07.050

    authors: Tang B,Kang P,Liu X,Liu Y,Liu Z,Wang B,Lv Y,Zhang L

    更新日期:2014-12-15 00:00:00

  • An exploratory study of the relationship between neurological soft signs and theory of mind deficits in schizophrenia.

    abstract::Indirect evidence suggests partially common pathogenetic mechanisms for Neurological Soft Signs (NSS), neurocognition, and social cognition in schizophrenia. However, the possible association between NSS and mentalizing impairments has not yet been examined. In the present study, we assessed the ability to attribute m...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.04.014

    authors: Romeo S,Chiandetti A,Siracusano A,Troisi A

    更新日期:2014-08-15 00:00:00

  • Aggregated COVID-19 suicide incidences in India: Fear of COVID-19 infection is the prominent causative factor.

    abstract::Many Indian COVID-19 suicide cases are turning the press-media attention and flooding in the social media platforms although, no particular studies assessed the COVID-19 suicide causative factors to a large extent. Therefore, the present study presents 69 COVID-19 suicide cases (aged 19 to 65 years; 63 cases were male...

    journal_title:Psychiatry research

    pub_type: 信件

    doi:10.1016/j.psychres.2020.113145

    authors: Dsouza DD,Quadros S,Hyderabadwala ZJ,Mamun MA

    更新日期:2020-08-01 00:00:00

  • Limited eye movement patterns in chronic schizophrenic patients.

    abstract::Eye movements of 29 chronic schizophrenic patients and 23 normal control subjects were measured by an eye mark recorder during viewing of stationary geometric figures. The results suggested that the eye movements of schizophrenic patients were more limited than those of normal control subjects and that the abnormal ey...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(89)90211-4

    authors: Kojima T,Potkin SG,Kharazmi M,Matsushima E,Herrera J,Shimazono Y

    更新日期:1989-06-01 00:00:00

  • The correlation between the quality of life and clinical variables among outpatients with schizophrenia.

    abstract::The study identifies the correlation between the quality of life (QoL) among outpatients with schizophrenia and clinical outcomes. A cross-sectional study design was used with 157 people with schizophrenia treated in outpatient clinics. Demographic, clinical and psychosocial variables were examined for their influence...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.09.062

    authors: Hasan AA

    更新日期:2019-01-01 00:00:00

  • Emotional intelligence as a mediator between rumination and suicidal ideation among depressed inpatients: The moderating role of suicidal history.

    abstract::Suicide is a substantial public health problem, and it remains a serious cause of death in the world. Therefore, this study was designed to examine the relationships between brooding, reflection, emotional intelligence (assessed by performance-based test), and suicidal ideation; the mediation role of emotional intelli...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.05.046

    authors: Abdollahi A,Talib MA

    更新日期:2015-08-30 00:00:00

  • Impaired mismatch negativity is associated with current functional status rather than genetic vulnerability to schizophrenia.

    abstract::The aim of this study is to investigate whether mismatch negativity (MMN) is associated with functional status or is a state-independent trait for schizophrenia. We assessed MMN in 26 patients with schizophrenia, 20 healthy subjects with high genetic loading, and 48 healthy controls. Repeated measures analysis of vari...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2014.02.012

    authors: Kim M,Kim SN,Lee S,Byun MS,Shin KS,Park HY,Jang JH,Kwon JS

    更新日期:2014-04-30 00:00:00

  • Clarity out of chaos: Use of theory in implementation research.

    abstract::Implementation science has been recognized as a potential catalyst for health system reform, in part, because of its contribution of well-grounded conceptual theories, often encapsulated in frameworks. Well-designed frameworks provide a semantic structure, a common language by which to guide systematic approaches to s...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2019.06.036

    authors: Damschroder LJ

    更新日期:2020-01-01 00:00:00

  • Outcomes, moderators, and mediators of empathic-emotion recognition training for complex conduct problems in childhood.

    abstract::Impairments in emotion recognition skills are a trans-diagnostic indicator of early mental health problems and may be responsive to intervention. We report on a randomized controlled trial of "Emotion-recognition-training" (ERT) versus treatment-as-usual (TAU) with N=195 mixed diagnostic children (mean age 10.52 years...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2012.04.033

    authors: Dadds MR,Cauchi AJ,Wimalaweera S,Hawes DJ,Brennan J

    更新日期:2012-10-30 00:00:00

  • Vocational functioning in schizotypal and paranoid personality disorders.

    abstract::Impaired vocational functioning is a hallmark of schizophrenia, but limited research has evaluated the relationships between work and schizophrenia-spectrum personality disorders, including schizotypal (SPD) and paranoid personality disorder (PPD). This study compared employment history and job characteristics of 174 ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.06.019

    authors: McGurk SR,Mueser KT,Mischel R,Adams R,Harvey PD,McClure MM,Look AE,Leung WW,Siever LJ

    更新日期:2013-12-15 00:00:00

  • Folate and MMA predict cognitive impairment in elderly stroke survivors: A cross sectional study.

    abstract::Elderly stroke survivors are at risk of malnutrition and long-term cognitive impairment. Vitamin B-related metabolites, folate and methylmalonic acid, have been implicated in cognitive function. We conducted a study exploring the relationship between blood folate, methylmalonic acid and post-stroke cognitive impairmen...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.06.008

    authors: Pascoe MC,Linden T

    更新日期:2016-09-30 00:00:00

  • Psychiatrists׳ fear of death is associated with negative emotions toward borderline personality disorder patients.

    abstract::This study examines the relationship between psychiatrists׳ fear of death and negative emotions toward patients with borderline personality disorder (BPD). A survey (N=120) demonstrated that fear of death is associated with stronger negative attitudes toward BPD patients, after controlling for attitudes toward suicide...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.06.010

    authors: Bodner E,Shrira A,Hermesh H,Ben-Ezra M,Iancu I

    更新日期:2015-08-30 00:00:00

  • Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis.

    abstract::Recent studies have suggested an increased risk of psoriasis among patients with schizophrenia although the results are still inconclusive. This systematic review and meta-analysis of cohort and case-control studies that compared the risk psoriasis among patients with schizophrenia versus subjects without schizophreni...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.psychres.2017.11.021

    authors: Ungprasert P,Wijarnpreecha K,Cheungpasitporn W

    更新日期:2018-01-01 00:00:00

  • Correlates of response to Olanzapine in a North Indian Schizophrenia sample.

    abstract::Olanzapine is widely used for the treatment of schizophrenia and is considered a first line medication in India. Along with other factors, the variation in response and side effects to this agent may be accounted for by genetic differences among patients. Olanzapine was administered for 6 weeks to Indian subjects with...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2007.09.010

    authors: Thomas P,Srivastava V,Singh A,Mathur P,Nimgaonkar VL,Lerer B,Thelma BK,Deshpande SN

    更新日期:2008-12-15 00:00:00

  • Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity.

    abstract::One of the central problems in posttraumatic stress disorder (PTSD) is the inability to suppress fear even under safe conditions. The neural underpinnings of fear are clinically relevant but poorly understood. This study assessed fear potentiation and fear inhibition using fear-potentiated startle in a conditional dis...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2007.12.014

    authors: Jovanovic T,Norrholm SD,Fennell JE,Keyes M,Fiallos AM,Myers KM,Davis M,Duncan EJ

    更新日期:2009-05-15 00:00:00

  • Progressive membrane phospholipid changes in first episode schizophrenia with high field magnetic resonance spectroscopy.

    abstract::Patients with a first episode of schizophrenia generally have increased phospholipid membrane breakdown products within the brain, while findings in chronic patients have been inconsistent. In this study we examine progressive changes in phosphorus membrane metabolites in the same patient group through the early years...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2011.06.017

    authors: Miller J,Drost DJ,Jensen E,Manchanda R,Northcott S,Neufeld RW,Menon R,Rajakumar N,Pavlosky W,Densmore M,Schaefer B,Williamson P

    更新日期:2012-01-30 00:00:00

  • Relationship between psychological inflexibility and experiential avoidance and internet addiction: Mediating effects of mental health problems.

    abstract::Internet addiction became a major mental health problem in college student. Our objective was to examine the relationship between psychological inflexibility and experiential avoidance (PIEA) and Internet addiction (IA) and the mediating effects of mental health problem indicators. 500 college students (238 men and 26...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.07.021

    authors: Chou WP,Lee KH,Ko CH,Liu TL,Hsiao RC,Lin HF,Yen CF

    更新日期:2017-11-01 00:00:00