Abstract：
:While cannabis is associated with positive syndrome schizophrenia (SZ), it is unclear whether cannabinoids are also related to negative symptoms such as affective blunting. We examined whether cannabis use is associated with schizotypy and utilized event-related potentials (ERPs) to assess affect processing. Cannabis users demonstrated increased P300 amplitudes for unpleasant trait words, and demonstrated higher positive syndrome schizotypy which correlated with levels of cannabis use. The cannabis group also exhibited lower negative syndrome schizotypy. The lack of blunted responses during the affect ERP and decreased negative subscale schizotypy scores provide evidence that the endocannabinoid theory of schizophrenia may be primarily relevant in relation to positive syndrome SZ.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Skosnik PD,Park S,Dobbs L,Gardner WLdoi
10.1016/j.psychres.2007.02.010subject
Has Abstractpub_date
2008-01-15 00:00:00pages
279-82issue
1-3eissn
0165-1781issn
1872-7123pii
S0165-1781(07)00040-6journal_volume
157pub_type
杂志文章abstract：:To access the saliva level of free 3-methoxy-4-hydroxyphenylglycol (MHPG) as a biological index of anxiety disorders, gender- or age-dependent changes in saliva MHPG level in patients with anxiety disorders were investigated. Saliva MHPG levels in 196 normal volunteers (59 male, 137 female) and 42 outpatients with anx...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(00)00118-9
更新日期：2000-04-10 00:00:00
abstract：:The primary aim of the present study was to assess the possible associations between dopaminergic, serotonergic, and glutamatergic system-related genes and adverse events after antipsychotic treatment in paranoid schizophrenia patients. The second aim of the study was to compare the intensity of these symptoms between...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2014.05.039
更新日期：2014-10-30 00:00:00
abstract：:B cell lymphoma protein-2 (Bcl-2) may contribute to the pathophysiology of bipolar disorder, and may be involved in the therapeutic action of anti-manic drugs. The aim of this study was to investigate serum levels of Bcl-2 in bipolar patients in a manic phase, and evaluate the Bcl-2 changes after treatment. We consecu...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.12.020
更新日期：2015-02-28 00:00:00
abstract：:While considerable data support the relationship between childhood trauma and adult personality pathology in general, there is little research investigating the specific relationships between different types of childhood maltreatment and adult personality disorders. The present study tested a model incorporating five ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.10.036
更新日期：2014-01-30 00:00:00
abstract：:Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores, and control subjects. Neuranatomical structures were measured using quantitative volumetric ana...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(93)90026-e
更新日期：1993-10-01 00:00:00
abstract：:The current study aimed to explore Israelis' state anxiety due to a Syrian-Israeli incident that occurred on February 10, 2018, when an Israeli F-16 fighter jet was shot down by Syrian air defense forces. In line with the "looming vulnerability" model which emphasizes the importance of the dynamic nature of psychologi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.10.072
更新日期：2018-12-01 00:00:00
abstract：:Schizophrenia is a chronic disorder that is usually characterized by relapses alternating with periods of full or partial remission. We examined whether combined therapy with a psychosocial intervention for relapse prevention (PIRP) and risperidone administered by long-acting injection (RLAI) would be more effective i...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/j.psychres.2008.06.043
更新日期：2010-02-28 00:00:00
abstract：:Past research has found that deficits in insight into illness are related to executive deficits in schizophrenia. This study further explores this relationship with the utilization of an ecologically-valid battery of executive tests. The study included 21 patients with schizophrenia who were administered the Behaviour...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.09.012
更新日期：2007-05-30 00:00:00
abstract：:Family, adoption, and twin studies have demonstrated the involvement of genetic factors in the etiology of major affective disorders. In an attempt to identify the involved genes, several linkage and association studies have focused on the gene coding for tyrosine hydroxylase, the rate-limiting enzyme in catecholamine...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(96)02888-0
更新日期：1996-09-27 00:00:00
abstract：:Posttraumatic stress disorder (PTSD) is a severe psychiatric disorder prevalent in combat veterans. Previous neuroimaging studies have demonstrated that patients with PTSD exhibit abnormal responses to non-threatening visual and auditory stimuli, but have not examined somatosensory processing. Thirty male combat veter...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2015.06.012
更新日期：2015-08-30 00:00:00
abstract：:The relationship between severity of tardive dyskinesia (TD) and the prominence of negative symptoms was assessed in 25 right-handed, medicated schizophrenic patients. TD was quantified using ultrasound detectors and frequency measurement techniques as well as with observer rating scales. Electromechanical studies rev...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(89)90042-5
更新日期：1989-05-01 00:00:00
abstract：:Serotonergic abnormalities have been regularly reported in the brains of suicide victims. Because of evidence that pineal function is altered in depressed subjects and that serotonin-releasing axons may innervate the pineal, we assayed tritiated serotonin binding in a series of control and suicide pineals. High affini...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(90)90131-n
更新日期：1990-04-01 00:00:00
abstract：:Patients with schizophrenia are affected more adversely than healthy controls by distracting conditions, due to their inability to adequately apportion attentional resources to targets or distractors. We attempted to re-evaluate the effects of distractors in 25 patients with chronic schizophrenia and in 12 controls. T...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2005.07.017
更新日期：2005-11-15 00:00:00
abstract：:A great deal of variation in opinion and practice remains regarding the most efficient use of electroconvulsive therapy (ECT) in treating depression. In this study we used an estimate of maximal improvement point to look at the rate of response to conventional ECT (one seizure per session, three times per week) in 66 ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(84)90065-9
更新日期：1984-03-01 00:00:00
abstract：:A woman complained of feeling a "metal-like thing" in her oral cavity 4 years after a stroke. She was convinced of the physical nature of her complaint despite intact dental and neurological findings. Somatosensory evoked magnetic fields suggested that her decreased right SII function was compensated for by the right ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2005.10.003
更新日期：2006-01-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.09.083
更新日期：2017-12-01 00:00:00
abstract：:Presynaptic dopamine metabolism was studied in a group of patients with schizophrenia and in an age- and gender-matched normal control group using 6-[(18)F]fluoro-L-DOPA ((18)F-DOPA) and positron emission tomography (PET). Nineteen patients, nine drug-free, 10 on neuroleptics, and 13 normal control subjects underwent ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(00)00064-0
更新日期：2000-11-20 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.11.018
更新日期：2012-07-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.08.031
更新日期：2017-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2017.06.027
更新日期：2017-10-01 00:00:00
abstract：:Pathological gamblers (PGs) perform differently on neurocognitive tests than do healthy controls (HC). The aim of this study was to assess "waiting ability" - a major components of inhibition control-using a modified Stop Signal Task (SST) in a population of male PGs (N=55), and HCs (N=53). Results indicated no differ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.09.038
更新日期：2015-12-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(85)90033-2
更新日期：1985-05-01 00:00:00
abstract：:Individuals with a more deprived socioeconomic status (SES) are more likely to have higher rates of psychiatric morbidity and use of psychiatric services. Such service use is also influenced by socioeconomic factors at the ecological level. The aim of this article is to investigate the influence of these variables on ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.02.031
更新日期：2013-10-30 00:00:00
abstract：:Impaired vocational functioning is a hallmark of schizophrenia, but limited research has evaluated the relationships between work and schizophrenia-spectrum personality disorders, including schizotypal (SPD) and paranoid personality disorder (PPD). This study compared employment history and job characteristics of 174 ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.06.019
更新日期：2013-12-15 00:00:00
abstract：:No prospective studies of first psychotic episodes have explored sex differences in smoking cessation. The aim of this study was to determine the influence of sex and substance abuse on smoking cessation during an 8-year follow-up of patients after a first psychotic episode. Logistic regression modeling was used to id...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.08.005
更新日期：2012-01-30 00:00:00
abstract：:Dissociative disorders are frequent comorbid conditions of other mental disorders. Yet, there is controversy about their clinical relevance, and little systematic research has been done on how they influence global functioning. Outpatients and day care patients (N=160) of several psychiatric units in Switzerland were ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.04.028
更新日期：2012-12-30 00:00:00
abstract：:Destination memory refers to the ability to remember to whom a piece of information was previously transmitted. Our paper assessed this ability in schizophrenia. Twenty-five patients with schizophrenia and 25 control participants told proverbs (e.g., "send a thief to catch a thief") to pictures of celebrities (e.g., E...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.12.023
更新日期：2017-02-01 00:00:00
abstract：:Patients with affective disorders frequently report problems with attention, concentration and memory, although little research has investigated subjective cognitive complaints relative to objective neuropsychological deficits. We compared subjective (self-rated) cognition and objective (clinician-rated) neuropsycholo...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.12.009
更新日期：2005-07-15 00:00:00
abstract：BACKGROUND:Evidence is emerging that early onset bipolar disorder and the duration of the delay to first treatment are both risk factors for poor treatment outcome. We report on the incidence and implications of these two risk factors in patients from the United States (US) versus Europe. METHODS:Age of onset and age ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113274
更新日期：2020-10-01 00:00:00
abstract：:Phodopus sungorus, the Siberian dwarf hamster, exhibits a number of reproducible and quantifiable behavioral changes when the members of a male-female pair bond are separated. Preliminary evaluation of the syndrome revealed a significant increase in body weight, decrease in social interaction, and decrease in explorat...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(84)90106-9
更新日期：1984-01-01 00:00:00
