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Medial temporal N-acetyl-aspartate in pediatric major depression.

Abstract：

:The medial temporal cortex (MTC) has been implicated in the pathogenesis of pediatric major depressive disorder (MDD). Eleven MDD case-control pairs underwent proton magnetic resonance spectroscopic imaging. N-acetyl-aspartate was lower in the left MTC (27%) in MDD patients versus controls. Lower N-acetyl-aspartate concentrations in MDD patients may reflect reduced neuronal viability.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

MacMaster FP,Moore GJ,Russell A,Mirza Y,Taormina SP,Buhagiar C,Rosenberg DR

doi

10.1016/j.pscychresns.2007.12.022

subject

Has Abstract

pub_date

2008-10-30 00:00:00

pages

86-9

issue

1

eissn

0165-1781

issn

1872-7123

pii

S0925-4927(08)00002-4

journal_volume

164

pub_type

杂志文章

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