Reinforcement learning deficits in people with schizophrenia persist after extended trials.

Abstract:

:Previous research suggests that people with schizophrenia have difficulty learning from positive feedback and when learning needs to occur rapidly. However, they seem to have relatively intact learning from negative feedback when learning occurs gradually. Participants are typically given a limited amount of acquisition trials to learn the reward contingencies and then tested about what they learned. The current study examined whether participants with schizophrenia continue to display these deficits when given extra time to learn the contingences. Participants with schizophrenia and matched healthy controls completed the Probabilistic Selection Task, which measures positive and negative feedback learning separately. Participants with schizophrenia showed a deficit in learning from both positive feedback and negative feedback. These reward learning deficits persisted even if people with schizophrenia are given extra time (up to 10 blocks of 60 trials) to learn the reward contingencies. These results suggest that the observed deficits cannot be attributed solely to slower learning and instead reflect a specific deficit in reinforcement learning.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Cicero DC,Martin EA,Becker TM,Kerns JG

doi

10.1016/j.psychres.2014.08.013

subject

Has Abstract

pub_date

2014-12-30 00:00:00

pages

760-4

issue

3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(14)00709-4

journal_volume

220

pub_type

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