Abstract：
:The present study introduces a novel measure of adenosine receptor sensitivity that is based on the action of specific receptor blockers (e.g., caffeine) to potentiate the ability to detect threshold quinine concentrations. The test is used to compare gustatory adenosinergic responses to caffeine challenges in normal controls and patients with panic disorder or posttraumatic stress disorder (PTSD). Panic disorder patients had an exaggerated response to the caffeine challenge that was not found in controls or PTSD patients, although the latter had higher anxiety scores on psychometric tests. The results are related to a model in which A1-adenosine receptors up-regulate in an attempt to modulate hyperactive excitatory neuronal systems.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
DeMet E,Stein MK,Tran C,Chicz-DeMet A,Sangdahl C,Nelson Jdoi
10.1016/0165-1781(89)90014-0subject
Has Abstractpub_date
1989-12-01 00:00:00pages
231-42issue
3eissn
0165-1781issn
1872-7123pii
0165-1781(89)90014-0journal_volume
30pub_type
杂志文章abstract：:Previous research suggests that trauma may contribute to psychosis onset. In this study, we examine the effect of parental loss of a child on the onset of psychotic experience using data from the National Comorbidity Survey Replication, hypothesizing that child loss will precede the onset of psychosis and will be asso...
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abstract：:Electroconvulsive therapy (ECT) is effective in treatment-resistant depression (TRD). It may act through intracellular process modulation, but its exact mechanism is still unknown. Animal research supports a neurotrophic effect for ECT. We aimed to investigate the association between changes in serum brain-derived neu...
journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
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doi：10.1016/j.psychres.2015.06.029
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.04.008
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journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.08.029
更新日期：2011-03-30 00:00:00
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journal_title：Psychiatry research
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doi：10.1016/0165-1781(88)90096-0
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(88)90164-3
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journal_title：Psychiatry research
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doi：10.1016/j.psychres.2012.04.010
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journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
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更新日期：2013-03-30 00:00:00
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journal_title：Psychiatry research
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doi：10.1016/j.psychres.2017.03.056
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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abstract：:Numerous studies have documented a significant association between symptom severity and cognitive functioning in bipolar disorder (BD). These findings advanced speculations about a potential link between the physiological stress associated with illness severity and cognitive dysfunction. To explore this hypothesis, th...
journal_title：Psychiatry research
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doi：10.1016/j.psychres.2014.07.059
更新日期：2014-12-30 00:00:00
abstract：:This study examined compulsive sexual behavior (CSB) and psychopathology in a treatment-seeking sample of men in São Paulo, Brazil. Eighty-six men (26% gay, 17% bisexual, 57% heterosexual) who met diagnostic criteria for excessive sexual drive and sexual addiction completed assessments consisting of the Mini Internati...
journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
abstract：:Research suggests that those with antisocial tendencies are larger than controls, but studies have not assessed this association in antisocial personality disorder (APD) or its hypothesized sub-types (i.e. adolescence-limited, late-onset). Height, weight, body mass index, bulk, and psychosocial adversity were assessed...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(01)00344-4
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