Abstract:
:This report presents the simultaneous pattern of cerebral blood flow and cerebral glucose metabolism in two patients with a major depressive disorder who were undergoing continuation ECT. The regional cerebral blood flow and regional cerebral metabolic rate of these patients were imaged using double isotope 18F-FDG and 99mTc-HMPAO single-photon emission computed tomography before acute ECT and after the completion of continuation ECT; bilateral electrode placement (11 and 12 sessions, respectively) was chosen for the acute treatment course whereas unilateral placement was the method chosen during the continuation phase (6 and 7 sessions, respectively). Baseline SPECT scans of our patients, who continued to receive treatment with medication, were normal as compared with controls; however, scans at the end of continuation ECT revealed decreased uptake activities of both isotopes in prefrontal regions on both sides, which might be associated with the therapeutic impact and efficacy. These results are consistent with previous brain imaging studies of acute ECT. Furthermore, marked changes in both basal ganglia regions were found. The pattern of the isotope uptake ratios did not show any similarities to neurodegenerative processes, which might confirm the high safety profile of ECT also during the continuation phase of treatment.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Conca A,Prapotnik M,Peschina W,König Pdoi
10.1016/s0925-4927(03)00077-5subject
Has Abstractpub_date
2003-11-30 00:00:00pages
191-8issue
3eissn
0165-1781issn
1872-7123pii
S0925492703000775journal_volume
124pub_type
杂志文章abstract::We wished to determine whether decreases in prefrontal glutamate concentrations occur in offspring of parents with bipolar disorder with and at high risk for mania. Sixty children and adolescents, 9-18 years old, of parents with bipolar I or II disorder (20 offspring with established history of mania, "BD", 20 offspri...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.01.003
更新日期:2010-05-30 00:00:00
abstract::Although many studies have attempted to determine whether early object loss influences the risk of developing major affective illness in adulthood, there are few empirical data relating early loss to subsequent hypothalamic-pituitary-adrenal (HPA) axis dysfunction in adulthood. Forty-five psychiatric inpatients admitt...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(92)90026-y
更新日期:1992-12-01 00:00:00
abstract::Patients with schizophrenia can have difficulty recognizing emotion, and the impact of this difficulty on social functioning has been widely reported. However, earlier studies did not thoroughly explore how this deficit may vary according to emotion intensity, or how it may differ among individuals and across cultures...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.03.030
更新日期:2019-05-01 00:00:00
abstract::Several lines of evidence suggest disturbances of the hypothalamic-pituitary-adrenal (HPA) system in Alzheimer's disease (AD). In an exploration of the potential role of the glucocorticoid receptor (GR) in AD, GR density and affinity were assessed on mononuclear leukocytes of 12 AD patients and 12 healthy controls. GR...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90002-m
更新日期:1990-12-01 00:00:00
abstract::The aim of this study was to investigate the blood lead level and parental marital status that might influence the development of attention-deficit/hyperactivity disorder (ADHD) symptoms in school-aged children. The participants in the survey included elementary school children, and they were followed up biennially. T...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.01.002
更新日期:2016-02-28 00:00:00
abstract::Little is known about the demographic and clinical differences between early-onset (EOB) and late-onset bipolar disorders (LOB) in Chinese patients. This multi-center study examined the demographic and clinical characteristics of EOB (≤21 years) and LOB (>21 years) in China. A consecutively recruited sample of 555 pat...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2016.10.063
更新日期:2016-12-30 00:00:00
abstract::Previous studies have identified global associations between sleep quality and suicidal ideation. However, little is known regarding the relationship between sleep quality and suicidal ideation among Chinese older adults. We examined the relationship between sleep quality and suicidal ideation in older adults in China...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.07.017
更新日期:2017-10-01 00:00:00
abstract::The aims of this study were to: 1) examine the relationship between being bullied and depressive symptoms; 2) explore whether the three mentioned sources of social support moderated this association; and 3) examine gender differences in the moderating effects of social support on bullying-associated depressive symptom...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112676
更新日期:2020-02-01 00:00:00
abstract::Psychopathy is a cluster of personality traits associated with high rates of aggression. While research on psychopathic traits largely focuses on neurobiological factors implicated in aggression, other research suggests that contextual factors, such as social exclusion, also contribute to promoting aggression. Yet, th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.07.024
更新日期:2018-10-01 00:00:00
abstract::This study measured changes in regional cerebral blood flow (rCBF) during the complex cognitive task of meditation using single photon emission computed tomography. Eight experienced Tibetan Buddhist meditators were injected at baseline with 7 mCi HMPAO and scanned 20 min later for 45 min. The subjects then meditated ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(01)00074-9
更新日期:2001-04-10 00:00:00
abstract:PURPOSE:Since conduct problems (CP) vary distinctly across youths, better subtyping CP may be an important vehicle to study specific risk factors associated to differential patterns of CP. In a sample of 63,196 adolescents, we employed a two-step method to the identify such CP patterns and to help classify youths based...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113640
更新日期:2020-12-11 00:00:00
abstract::The objectives of this study were to evaluate the oral health of a group of schizophrenic outpatients and a control group without psychiatric illness. The study also aimed to assess the influence of positive and negative symptomatology on oral health among outpatients with schizophrenia. The DMF-T Index (sum of decaye...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.09.012
更新日期:2011-06-30 00:00:00
abstract::The present paper describes the development of the National Stressful Events Survey for PTSD-Short Scale (NSESSS-PTSD), a new self-report scale for PTSD that is brief (9 items), free of copyright restrictions, and consistent with DSM-5 diagnostic criteria. Study 1 describes the development of the NSESSS-PTSD scale ite...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.03.032
更新日期:2014-08-15 00:00:00
abstract::Imaging studies in patients with Type II alcohol dependence have revealed significant reductions in dopamine (DA) D2 receptor availability. Here we assessed the effects of alcohol detoxification in DA D2 receptors in alcoholic subjects. We evaluated 14 patients with Type II alcohol dependence tested within 6 weeks of ...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/s0925-4927(02)00087-2
更新日期:2002-12-30 00:00:00
abstract::One of the leading biosocial theories of borderline personality disorder (BPD) suggests that individuals with BPD have biologically based abnormalities in emotion regulation contributing to more intense and rapid responses to emotional stimuli, in particular, invalidation [Linehan, M.M., 1993. Cognitive-Behavioral Tre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.06.007
更新日期:2008-01-15 00:00:00
abstract::The current study examined whether there is a relationship between the dimension of delusion-proneness and performance on the color-word Stroop task. As dysfunction in the anterior cingulate cortex (ACC) has been related to both Stroop task performance and the presence of delusions in various psychiatric populations, ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.09.001
更新日期:2010-01-30 00:00:00
abstract::There is evidence from research based on self-report personality measures that schizophrenia patients tend to be lower in extraversion and higher in neuroticism than healthy individuals. Self-report personality measures assess aspects of the explicit self-concept. The Implicit Association Test (IAT) has been developed...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.04.023
更新日期:2014-08-30 00:00:00
abstract::Firefighters represent a unique, vulnerable population at high risk for alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) symptomatology due to the high rates of occupational exposure to traumatic events. To inform specialized alcohol use interventions for firefighters, it is important to understand ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112633
更新日期:2019-12-01 00:00:00
abstract::The heritability of some individual depressive symptoms has been well established. However, the causal genes related to individual depressive symptoms and genetic effects on the courses of individual depressive symptoms are still unclear. We examined these issues in 241 Korean patients who met the DSM-IV-TR criteria f...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/j.psychres.2011.12.037
更新日期:2012-08-15 00:00:00
abstract::We examined associations between social connections and non-suicidal self-injury (NSSI) among transgender/gender non-conforming (TGNC) youth. Data came from the 2016 Minnesota Student Survey (N = 2168). Logistic regression analyses determined connectedness factors associated with any past-year NSSI and repetitive NSSI...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.06.068
更新日期:2018-10-01 00:00:00
abstract::It has been shown that the dysfunction of N-methyl-d-asparate (NMDA) receptors-mediated neurotransmission plays a role in the pathophysiology of schizophrenia. Especially, GluN2B, a subunit of NMDA receptors, associated trafficking complex is altered in the prefrontal cortex of schizophrenia. The kinesin superfamily m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.09.031
更新日期:2015-12-15 00:00:00
abstract::The tryptophan catabolite (TRYCAT) pathway is induced by indoleamine 2,3-dioxygenase (IDO), which upon activation depletes plasma tryptophan (TRP) and increases the synthesis of TRYCATs. Both phenomena are associated with somatization and depression. The aims of this study are to examine whether disorders in the TRYCA...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.09.029
更新日期:2012-04-30 00:00:00
abstract::Previous functional neuroimaging studies of posttraumatic stress disorder (PTSD) have mainly focused on symptom-provocation paradigms in combat-related PTSD. We sought to elucidate the effect of non-combat-related PTSD on the physiology of social cognition. Thirteen patients with PTSD underwent functional magnetic res...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2005.05.012
更新日期:2005-10-30 00:00:00
abstract:INTRODUCTION:The aim of the study was to investigate mental health in university students in Greece, during lockdown due to COVID-19. MATERIAL AND METHODS:The data were collected online and anonymously, during lockdown; they included 1104 females (aged 22.08±4,96) and 431 males (aged 22.35±3.11). The analysis included...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113298
更新日期:2020-10-01 00:00:00
abstract::As they alleviate major depressive disorder, antidepressant therapies may improve associated sleep disturbances, but may also have inherent sedating or activating properties. We examined sleep changes during a multicenter, sham-controlled, trial of transcranial magnetic stimulation (TMS) therapy for pharmacoresistant ...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.psychres.2012.09.011
更新日期:2013-01-30 00:00:00
abstract::We aimed to assess the association between core cerebrospinal fluid (CSF) biomarkers, regional brain atrophy and clinical severity in the Alzheimer's disease (AD) continuum, as well as to investigate how cognitive reserve (CR) may modulate these putative associations. Forty-nine subjects (11 controls, 10 patients with...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.12.001
更新日期:2011-06-30 00:00:00
abstract::Suicidal behaviours are highly complex, multi-determined phenomena. Despite this, historically research has tended to focus on bivariate associations between atheoretical demographic and/or psychiatric factors and suicidal behaviour. The aim of this study was to empirically test the Integrated Motivational-Volitional ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.03.023
更新日期:2016-05-30 00:00:00
abstract::The main goal in the treatment of major depressive disorder (MDD) is to achieve remission, defined as the resolution of symptoms and the return to normal levels of functionality. However, the clinical assessment of remission is usually merely based on scores of symptomatic rating scales. One of the most widely used sc...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2010.06.023
更新日期:2011-03-30 00:00:00
abstract::In the past decade, not just right experiences (NJRE) and incompleteness (INC) have attracted renewed interest as putative motivators of symptoms in obsessive-compulsive disorder (OCD), beyond harm avoidance (HA). This study examines, in 267 non-clinical undergraduates and 47 OCD patients, the differential contributio...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.01.012
更新日期:2016-02-28 00:00:00
abstract::This study examined the effects of neuroleptic medication on the allocation of attentional resources to distracting stimuli in patients with schizophrenia. Twenty-five patients were tested twice (medication-free and after medication stabilization) on the Identical Pairs versions of the Continuous Performance Test unde...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02590-s
更新日期:1995-07-28 00:00:00