Abstract：
:One inhalation of 35% CO2 in oxygen was administered to 36 patients with anxiety disorders and 14 healthy controls. Eighteen patients had a diagnosis of panic disorder (PD) and 18 of obsessive-compulsive disorder (OCD). As a placebo control for CO2, compressed air was administered in a double-blind design. Immediately before and after the inhalation, levels of anxiety and DSM-III-R symptoms of panic were assessed. CO2 elicited high levels of subjective anxiety in the PD group. Patients with OCD were hardly affected by the inhalation, and did not differ from healthy controls. These results suggest that CO2 challenge should be considered as a specific probe for subjects with panic-anxiety. It is speculated that CO2 may trigger some as yet undefined mechanisms, possibly linked to ventilation control, which demarcate panic from other types of pathological anxiety.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Griez E,de Loof C,Pols H,Zandbergen J,Lousberg Hdoi
10.1016/0165-1781(90)90121-ksubject
Has Abstractpub_date
1990-02-01 00:00:00pages
193-9issue
2eissn
0165-1781issn
1872-7123pii
0165-1781(90)90121-Kjournal_volume
31pub_type
临床试验,杂志文章abstract：:Animal models and clinical trials in humans suggest that probiotics can have an anxiolytic effect. However, no studies have examined the relationship between probiotics and social anxiety. Here we employ a cross-sectional approach to determine whether consumption of fermented foods likely to contain probiotics interac...
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pub_type： 临床试验,杂志文章
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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更新日期：2008-05-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.02.013
更新日期：2010-04-30 00:00:00
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journal_title：Psychiatry research
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更新日期：2017-08-01 00:00:00
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pub_type： 杂志文章,meta分析,评审
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(89)90148-0
更新日期：1989-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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