Abstract：
:The aim of the present study was to evaluate subject and informant factors affecting the validity of the family history for dementia and depression. Relatives of patients and control subjects (n = 531) were interviewed directly. At least one 'significant' other provided family history information on every interviewed relative. The detection of dementia or depression based on the family history increased with the severity of the respective disorder. The likelihood of detecting dementia based on the family history increased in proportion to the subject's age. A lifetime diagnosis of depression in the informant improved the detection of this disorder in a relative. The presence of another psychiatric disorder in either the interviewed relative or the informant significantly increased the risk for false-positive diagnoses of depression. The present results demonstrate that family history information on depression and dementia is influenced by different proband and informant variables. On the basis of these results, we cannot recommend reducing thresholds for family history diagnoses.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Heun R,Maier W,Müller Hdoi
10.1016/s0165-1781(97)00058-9subject
Has Abstractpub_date
1997-08-08 00:00:00pages
175-80issue
3eissn
0165-1781issn
1872-7123pii
S0165-1781(97)00058-9journal_volume
71pub_type
杂志文章abstract：:The covid-19 pandemic has heavily burdened healthcare systems throughout the world. We performed a rapid systematic review to identify, assess and summarize research on the mental health impact of the covid-19 pandemic on HCWs (healthcare workers). We utilized the Norwegian Institute of Public Health's Live map of cov...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113441
更新日期：2020-11-01 00:00:00
abstract：:In the search for a less expensive alternative to magnetic resonance imaging (MRI), which is contraindicated in some patients, we evaluated the accuracy of an individualized MR template-based head model in terms of navigated brain stimulation system targeting. The mean error between the identification of target points...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2011.12.013
更新日期：2012-07-30 00:00:00
abstract：:A study of weight change in subjects treated with imipramine was performed on recurrent depressive outpatients. The patients (n = 52) were treated with imipramine (200-250 mg/day) and psychotherapy for 16 weeks. Each individual was weighed upon entry to the study (drug-free) and then weekly thereafter for 16 weeks. Of...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(86)90074-0
更新日期：1986-04-01 00:00:00
abstract：:Previous studies have shown that various factors, such as genetic and environmental factors, contribute to the development of major depressive disorder (MDD). The aim of this study is to clarify how multiple factors, including affective temperaments, childhood abuse and adult life events, are involved in the severity ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.12.016
更新日期：2016-02-28 00:00:00
abstract：:Previous studies have suggested that schizophrenic psychopathology segregates into three orthogonal dimensions, viz., psychosis, negative and disorganization. Most of these reports were based on studies on medicated patients with varying degrees of chronicity. The present study aimed at exploring the dimensionality of...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00199-9
更新日期：2003-11-01 00:00:00
abstract：:The presence of an anxiety disorder is associated with greater frequency of suicidal thoughts and behaviors. Given the high personal and societal costs of suicidal behaviors, suicide prevention is a priority. Understanding factors present within individuals with anxiety disorders that increase suicide risk may inform ...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2013.03.017
更新日期：2013-08-30 00:00:00
abstract：:Post-traumatic Stress Disorder (PTSD) and Major Depressive Disorder (MDD) are the most common psychiatric consequences among caregivers of pediatric patients affected by severe chronic illnesses. The aims of this study were to describe rates of PTSD and MDD in a sample of parents of epileptic children, and to examine ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.02.062
更新日期：2019-09-01 00:00:00
abstract：:The reliability and validity of the Toronto Structured Interview for Alexithymia (TSIA) have been demonstrated in previous studies with English-speaking community and psychiatric samples and a German-speaking psychiatric sample. The aim of this study was to evaluate the psychometric properties of the TSIA in a mixed c...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.02.015
更新日期：2011-05-30 00:00:00
abstract：:Cognitive impairment is a frequent complication of advanced human immunodeficiency virus-1 (HIV-1) infection. However, structural imaging of the brain has not revealed abnormalities that precede the onset of clinical abnormalities. Cranial magnetic resonance (MR) studies were performed in 28 male subjects with intrave...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(93)90047-k
更新日期：1993-05-01 00:00:00
abstract：:The activity of phosphatidylinositol-specific phospholipase C was significantly reduced in platelets obtained from 20 euthymic manic-depressive patients on therapeutic lithium doses (mean blood level 0.85 mEq/l) compared to an age- and sex-matched group of 36 control subjects. The activities of prostaglandin E1-, alum...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(88)90138-2
更新日期：1988-04-01 00:00:00
abstract：:Major depression and Alzheimer׳s disease (AD) are often observed in the elderly. The identification of specific markers for these diseases could improve their screening. The aim of this study was to investigate long-term odor recognition memory in depressed and AD patients, with a view to identifying olfactory markers...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.08.050
更新日期：2014-12-30 00:00:00
abstract：:Depressive symptoms are associated with deficits in objectively-rated detail and specificity in autobiographical future thinking for personally-relevant events. However, how depressive symptoms might affect the subjective, phenomenal characteristics of future thinking in general is not well understood. This study exam...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.12.100
更新日期：2019-03-01 00:00:00
abstract：:Magnetic resonance (MR) imaging now allows the qualitative and quantitative assessment of the human brain in vivo. As MR imaging resolution has improved, precise measurement of small brain structures has become possible. Methods of measuring brain regions from MR images include both manual and semiautomated methods. D...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(96)02790-4
更新日期：1996-10-07 00:00:00
abstract：:Recent studies suggest a higher threshold number of self-injuries during the past year than the one proposed in the DSM-5 criteria for non-suicidal self-injury disorder (NSSID). Therefore, we aimed to test a validity of the frequency criterion in girls with conduct disorder (CD) based on psychopathology and the level ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.05.054
更新日期：2018-09-01 00:00:00
abstract：:Knowledge of how specific neurocognition (NC) abilities predict social cognition (SC) in schizophrenia has potential to guide novel integrated cognitive-remediation therapies. The scope of studies conducted in this field is limited as they have not examined a comprehensive set of SC domains and they employ small sampl...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.05.055
更新日期：2014-10-30 00:00:00
abstract：:The medical and psychosocial comorbidity of two core features of night eating syndrome (NES), evening hyperphagia (EH) and nocturnal awakening and ingestion of food (NI), was evaluated in adults enrolled in the Swedish Twin Study of Adults: Genes and Environment (STAGE) study. As part of the STAGE study, more than 20,...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.04.010
更新日期：2012-09-30 00:00:00
abstract：:Quantitative electroencephalographic (QEEG) analyses are presented for a group of 90 subjects recovering from polysubstance abuse (median = 90 days abstinent) who preferentially used cocaine. QEEGs showed significant decreases from normal in both absolute and relative delta power and decreased theta power in both abso...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(95)02474-b
更新日期：1995-10-16 00:00:00
abstract：:Alexithymia is common in patients with a substance use disorder (SUD) and is possibly a negative prognostic factor in their treatment. The aim of this study was twofold. First, we explored whether SUD patients with posttraumatic stress disorder (PTSD) are more alexithymic than SUD patients without PTSD. Next, we explo...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112634
更新日期：2019-12-01 00:00:00
abstract：:We report the results of a high-density attempted suicide association study of the X chromosome, which genotyped 23,141 SNPs on 983 attempters and 1143 non-attempters and generated modest evidence for association for SH3KBP1 (P=1.07×10(-4)) and GRIA3 (P=4.01×10(-4)). These findings highlight the need for larger sample...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.06.001
更新日期：2012-12-30 00:00:00
abstract：:Most investigators have measured binding of 3H-imipramine to platelet membranes, but some of the preparations may have contained varying proportions of intracellular protein because of contamination with incompletely lysed platelets. Since binding to membranes has been expressed with reference to the amount of protein...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(88)90070-4
更新日期：1988-11-01 00:00:00
abstract：:Executive functions play an important role in problem-solving and self-control. Set-shifting is an aspect of executive functioning and represents cognitive flexibility. The inability to control eating in Binge Eating Disorder (BED) may imply deficits in set-shifting which could be exacerbated by negative mood and depr...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.psychres.2015.09.001
更新日期：2015-12-15 00:00:00
abstract：:The study identifies the correlation between the quality of life (QoL) among outpatients with schizophrenia and clinical outcomes. A cross-sectional study design was used with 157 people with schizophrenia treated in outpatient clinics. Demographic, clinical and psychosocial variables were examined for their influence...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.09.062
更新日期：2019-01-01 00:00:00
abstract：:This study examined affective and psychological routes from childhood maltreatment to increased paranoia in adulthood. Recent anxiety and negative beliefs about the self partially accounted for the associations between emotional or physical abuse and paranoia. However, as full mediation did not occur, other psychologi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.12.004
更新日期：2012-04-30 00:00:00
abstract：:Ictal heart rate (HR) and postictal suppression in ictal EEG are believed to be predictive of the therapeutic efficacy of eletroconvulsive therapy (ECT) for depression. However, regarding ictal peak HR, previous studies investigated ictal HR on only one or two occasions during the course of ECT. We prospectively exami...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.05.007
更新日期：2011-02-28 00:00:00
abstract：:Pituitary volume in humans has been reported to change size in response to experimental manipulations of photoperiod, and to be increased during an episode of non-seasonal major depression. We wanted to determine whether pituitary volume changes either across the seasons or during an episode of winter depression. Nine...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(97)00015-2
更新日期：1997-07-04 00:00:00
abstract：:Precise rules for locating the anatomical boundaries of the dorsolateral prefrontal cortex (DLPFC) or its subdivisions, i.e., superior, inferior and middle frontal gyri (SFG, IFG and MFG) on magnetic resonance images (MRI), have not been defined. The present study describes the inter-rater reliability of manual segmen...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2006.05.006
更新日期：2006-12-01 00:00:00
abstract：:We developed a physical exercise intervention aimed at improving multiple determinants of physical performance in severe mental illness. A sample of 12 (9M, 3F) overweight or obese community-dwelling patients with schizophrenia (n=9) and bipolar disorder (n=3) completed an eight-week, high-velocity circuit resistance ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.07.007
更新日期：2015-09-30 00:00:00
abstract：:Eating disorders (EDs) are psychiatric disorders associated with high morbidity and mortality. It is well established that patients with anorexia nervosa (AN) have an increased risk of premature death, whereas mortality data are lacking for the other EDs. This study aimed to establish mortality rates in a sample of ED...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.08.032
更新日期：2015-12-15 00:00:00
abstract：:The first of its kind, this study determined whether blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress (PTS) symptoms in 78 military explosives operators. In all models, blast-exposed 5HTTLPR S carriers registered definitively higher PTS symptoms in comparison to non-exposed S carri...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112519
更新日期：2019-10-01 00:00:00
abstract：:Although the expressions of both positive and negative symptoms in schizophrenia spectrum illnesses can each occur with varying degrees of severity, researchers have often dichotomized patients as generally positive or negative subtypes. Studies of schizophrenia and schizotypal personality disorder (SPD) have not typi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(98)00101-2
更新日期：1998-11-16 00:00:00
