Abstract：
:The presence of an anxiety disorder is associated with greater frequency of suicidal thoughts and behaviors. Given the high personal and societal costs of suicidal behaviors, suicide prevention is a priority. Understanding factors present within individuals with anxiety disorders that increase suicide risk may inform prevention efforts. The aims of the present study were to examine the prevalence of suicidal ideation and behaviors, as well as factors associated with suicide risk in patients with anxiety disorders in primary care. Data from a large scale randomized controlled study were analyzed to assess prevalence of suicidal thoughts and behaviors, as well as factors associated with suicide risk. Results revealed that suicidal ideation and behaviors were relatively common in this group. When examining mental and physical health factors jointly, presence of depression, mental health-related impairment, and social support each uniquely accounted for variance in suicide risk score. Methodological limitations include cross-sectional data collection and lack of information on comorbid personality disorders. Moreover, patients included were from a clinical trial with exclusion criteria that may limit generalizability. Results highlight the complex determinants of suicidal behavior and the need for more nuanced suicide assessment in this population, including evaluation of comorbidity and general functioning.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Bomyea J,Lang AJ,Craske MG,Chavira D,Sherbourne CD,Rose RD,Golinelli D,Campbell-Sills L,Welch SS,Sullivan G,Bystritsky A,Roy-Byrne P,Stein MBdoi
10.1016/j.psychres.2013.03.017subject
Has Abstractpub_date
2013-08-30 00:00:00pages
60-5issue
1eissn
0165-1781issn
1872-7123pii
S0165-1781(13)00148-0journal_volume
209pub_type
杂志文章,随机对照试验abstract：:Human corticotropin releasing hormone (h-CRH) was administered to 14 patients with major depression, after premedication with an overnight dose of 1.5 mg dexamethasone. Cortisol response, expressed as area under the time course curve (AUC), was significantly higher in the 14 patients than in a group of 13 age-matched ...
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