Abstract:
:Patients with affective disorders frequently report problems with attention, concentration and memory, although little research has investigated subjective cognitive complaints relative to objective neuropsychological deficits. We compared subjective (self-rated) cognition and objective (clinician-rated) neuropsychological functioning in 37 DSM-IV bipolar outpatients. Subjects completed three standardized self-report inventories: the Cognitive Difficulties Scale (CDS), Cognitive Failures Questionnaire (CFQ), and Patient's Assessment of Own Functioning (PAOF). These were followed by a systematic neuropsychological test battery. More than 75% of our sample of bipolar patients displayed some cognitive deficits, most notably in the domains of verbal learning and memory. In general, patients' self-reports of impairment failed to reliably predict objective neuropsychological deficits. Mood ratings for mania and depression were not significantly correlated with any of the self-report inventories or the objective neuropsychological variables. The findings suggest that most bipolar patients demonstrate objective signs of cognitive impairment, but they are unable to report them accurately, at least using available self-report inventories. Such discrepancies could relate to impaired insight, efforts to conceal deficits, or to subthreshold affective symptoms.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Burdick KE,Endick CJ,Goldberg JFdoi
10.1016/j.psychres.2004.12.009subject
Has Abstractpub_date
2005-07-15 00:00:00pages
43-50issue
1eissn
0165-1781issn
1872-7123pii
S0165-1781(05)00153-8journal_volume
136pub_type
杂志文章abstract::Elderly stroke survivors are at risk of malnutrition and long-term cognitive impairment. Vitamin B-related metabolites, folate and methylmalonic acid, have been implicated in cognitive function. We conducted a study exploring the relationship between blood folate, methylmalonic acid and post-stroke cognitive impairmen...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.06.008
更新日期:2016-09-30 00:00:00
abstract::Panic disorder (PD) and social phobia (SP) share many clinical, demographic and biological characteristics. To investigate the relationships between the two disorders, the responses to inhalation of a 35% carbon-dioxide (CO2) and 65% oxygen (O2) gas mixture were assessed. Sixteen patients with PD, 16 patients with SP,...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-1781(97)00038-3
更新日期:1997-06-16 00:00:00
abstract::We have previously reported that the activity in platelets of the important antioxidant enzyme glutathione peroxidase (GPx) is inversely correlated with computed tomographic (CT) measures of brain atrophy in a population of patients with chronic schizophrenia, suggesting that low GPx may be a vulnerability factor in t...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90103-c
更新日期:1990-01-01 00:00:00
abstract::Affective touch is important for social interaction within families and groups and there is evidence that unmyelinated C tactile fibers are involved in this process. Individuals with autism spectrum disorders show alterations in the perception and processing of affective touch. sThus, we hypothesized that affective to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.09.011
更新日期:2016-11-30 00:00:00
abstract::Predicting the outcome of antidepressant treatment by pre-treatment features would be of great usefulness for clinicians as up to 50% of major depressives may not have a satisfactory response in spite of adequate trials of antidepressant drugs. In the present article we compared a linear multivariate model of predicto...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.07.009
更新日期:2007-08-30 00:00:00
abstract::A number of studies measured lead levels in hair from children with autism spectrum disorder (ASD) to detect the relationship between cumulated lead exposure and the development of ASD, but results are inconsistent. We aimed to conduct a systematic review and meta-analysis using the published studies to explore the ac...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2019.05.022
更新日期:2019-06-01 00:00:00
abstract::The present study was designed to detect the anti-depressant effects of paeonol and the possible mechanisms in the lipopolysaccharide-induced depressive-like behavior. Open-field test(OFT), tail suspension test(TST) and forced swimming test(FST) were used to evaluate the behavioral activity. The contents of 5-hydroxyt...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.02.033
更新日期:2016-04-30 00:00:00
abstract::The pathophysiology of pediatric bipolar disorder (PBD) impacts both affective and cognitive brain systems. Understanding disturbances in the neural circuits subserving these abilities is critical for characterizing developmental aberrations associated with the disorder and developing improved treatments. Our objectiv...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2007.10.003
更新日期:2008-04-15 00:00:00
abstract::Religion and/or spirituality (R/S) can play a vital, multifaceted role in mental health. While beliefs about God represent the core of many psychiatric patients' meaning systems, research has not examined how internalized images of the divine might contribute to outcomes in treatment programs/settings that emphasize m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.05.003
更新日期:2017-08-01 00:00:00
abstract::Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00185-9
更新日期:2003-09-30 00:00:00
abstract::There is a growing recognition of the importance of encouraging patients with mental health problems to become more active as an efficacious strategy to reduce the disability-associated burden. The aim of the current study was to investigate if there are differences in quality of life (QoL) outcomes between people wit...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.041
更新日期:2017-12-01 00:00:00
abstract::We aimed to assess the association between core cerebrospinal fluid (CSF) biomarkers, regional brain atrophy and clinical severity in the Alzheimer's disease (AD) continuum, as well as to investigate how cognitive reserve (CR) may modulate these putative associations. Forty-nine subjects (11 controls, 10 patients with...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.12.001
更新日期:2011-06-30 00:00:00
abstract::Negative symptoms have been associated with frontal lobe dysfunction in schizophrenia. However, neuropsychological studies that evaluated the correlation between performance in tests sensitive to the dorsolateral prefrontal cortex (DLPFC) and negative symptoms have shown inconsistent results. Growing evidence has appe...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.03.002
更新日期:2007-08-30 00:00:00
abstract::Time perception (TP) impairment in schizophrenia has been originally described by clinicians and afterwards addressed in laboratory. Previous studies generally observed that schizophrenia patients overestimate time and that their timing sensitivity is impaired. However, because of the disease cognitive impairments, no...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.06.008
更新日期:2012-12-30 00:00:00
abstract::This study measured changes in regional cerebral blood flow (rCBF) during the complex cognitive task of meditation using single photon emission computed tomography. Eight experienced Tibetan Buddhist meditators were injected at baseline with 7 mCi HMPAO and scanned 20 min later for 45 min. The subjects then meditated ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(01)00074-9
更新日期:2001-04-10 00:00:00
abstract::We investigated the kinetic parameters of serotonin (5-HT) uptake into platelets in a group of 26 drug-naïve patients suffering from major depression before and after 3-7 weeks of treatment with citalopram. The degree of depression was rated using the Hamilton Depression Rating Scale (HDRS). The 5-HT uptake characteri...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.06.022
更新日期:2008-11-30 00:00:00
abstract::In this study 117 panic disorder patients were divided into a respiratory subtype group and a non-respiratory subtype group. The respiratory subtype patients were observed to be more sensitive to the 35% CO(2) inhalation challenge test and the hyperventilation test than the non-respiratory subtype patients. ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.07.015
更新日期:2008-01-15 00:00:00
abstract::Although deep grey matter (GM) involvement in multiple sclerosis (MS) is well documented, in-vivo multi-parameter magnetic resonance imaging (MRI) studies and association with detailed cognitive measures are limited. We investigated volumetric, diffusion and perfusion metrics in thalamus, hippocampus, putamen, caudate...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.10.004
更新日期:2015-12-30 00:00:00
abstract::In recent years, there has been increased interest in a clinical syndrome characterized by excessive sexual thoughts, sexual urges, and/or sexual behaviors that has many aspects in common with impulse control disorders. This study provides a preliminary examination of the impulsive aspects of this syndrome, compulsive...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2009.04.008
更新日期:2009-11-30 00:00:00
abstract::Functional disconnectivity during the resting state has been observed in subjects with major depressive disorder (MDD), and in subjects at high genetic risk for major depression during task performance. It is hypothesized that functional impairments in certain brain areas are present in patients with MDD and in their ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.03.004
更新日期:2010-06-30 00:00:00
abstract::Wells's (2009) metacognitive theory suggests that inflexible and recurrent styles of thinking in response to negative thoughts, feelings, and beliefs underlie mood and anxiety symptoms. Wells termed such styles of thinking as the cognitive attentional syndrome (CAS). Using a clinical sample (N=132) of patients with ei...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.04.020
更新日期:2013-11-30 00:00:00
abstract::Neuropsychological performance was examined in a sample of 100 children between the ages of 6 and 18 years who met DSM-III-R criteria for Tourette's syndrome. Neuropsychological test scores were converted to age-corrected t scores based on published normative data. Ratings of Tourette's symptoms were also obtained. Th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(90)90150-4
更新日期:1990-07-01 00:00:00
abstract::Acute Stress Disorder (ASD) was first included in the DSM-IV in 1994. It was proposed to account for traumatic responding in the early post trauma phase and to act as an identifier for later Posttraumatic Stress Disorder (PTSD). Unlike PTSD it included a number of dissociative indicators. The revised DSM-5 PTSD criter...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.11.063
更新日期:2015-02-28 00:00:00
abstract::The aim of this study was to evaluate the relationships between coping strategies and four dimensions of quality of life (QOL) (physical, psychological, social relations and environment) among military wives. We examined these links six months after the military operation termed Protective Edge. Data were collected fr...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.04.037
更新日期:2017-08-01 00:00:00
abstract::Computed axial brain tomograms were recorded in four groups of subjects: (a) subjects who had never taken benzodiazepines (n = 25); (b) subjects who had taken them in the past for less than a year (n = 9); (c) patients currently taking benzodiazepines (n = 30); and (d) patients who had taken benzodiazepines in the pas...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(93)90037-h
更新日期:1993-08-01 00:00:00
abstract::To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seekin...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-1781(93)90108-s
更新日期:1993-07-01 00:00:00
abstract::Impairments on neuropsychological and eye movement tasks have been demonstrated in schizophrenic patients and also reported in their unaffected relatives. However, it is not clear to what extent these phenotypes overlap. This study examined the relationship between specific eye movement and neuropsychological measures...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.05.008
更新日期:2009-08-15 00:00:00
abstract::Social cognition is impaired in schizophrenia, is relatively independent of purely neurocognitive domains such as attention and executive functioning, and may be the strongest predictor of functional outcome in this disease. Within a motivated reasoning framework, we tested the hypothesis that the anti-inflammatory Th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.02.030
更新日期:2017-05-01 00:00:00
abstract::Impaired visual integration is well documented in schizophrenia and related to functional outcomes. However, it is unclear if this deficit is specific to schizophrenia, or characteristic of psychosis more broadly. To address this question, this study used a Bayesian model comparison approach to examine the evidence of...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.061
更新日期:2018-07-01 00:00:00
abstract::Normal brain activity is associated with task-related pH changes. Although central nervous system syndromes associated with significant acidosis and alkalosis are well understood, the effects of less dramatic and chronic changes in brain pH are uncertain. One environmental factor known to alter brain pH is the extreme...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.04.002
更新日期:2014-06-30 00:00:00