Abstract：
:Comparative studies are needed to determine whether the cognitive impairments found in various psychiatric disorders are specific to those disorders, or are a more universal consequence of mental illness. This study compares the patterns of cognitive dysfunction in two conditions characterized by working memory dysfunction, schizophrenia and posttraumatic stress disorder (PTSD). Three matched groups (Schizophrenia, PTSD, Control) of 16 subjects had event related potentials recorded, using a 27 electrode array, while they performed a working memory auditory target detection task. Both disorders were associated with impaired task performance, with greater impairment in schizophrenia. Reduction in N1 amplitude was found only in schizophrenia, and an increase in target N2 amplitude and latency was found only in PTSD. Both patient groups showed a reduction in the amplitude of the non-target and target P3, but the groups were distinguished by a reduction in non-target parietal P3 amplitude in the schizophrenia group and a reduction in target P3 amplitude over the left posterior parietal region in the PTSD Group. This study demonstrates that there are specific patterns of cognitive dysfunction associated with schizophrenia and with PTSD.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Galletly CA,McFarlane AC,Clark Rdoi
10.1016/j.psychres.2007.04.001subject
Has Abstractpub_date
2008-05-30 00:00:00pages
196-206issue
1-2eissn
0165-1781issn
1872-7123pii
S0165-1781(07)00110-2journal_volume
159pub_type
杂志文章abstract：:Persistent infection with Herpes Simplex viruses (HSV) and other brain infections is consistently associated with cognitive impairment. These infections can also affect sleep. Thus, sleep abnormalities could explain the cognitive dysfunction. We investigated the association between sleep variables and persistent HSV-1...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112502
更新日期：2019-10-01 00:00:00
abstract：:The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well-characterized community sample of individuals with a current depressive episode. This is a cross-sectional study with young adults aged 24-30 years old. Depressive episode and the presence of anhedonia was ass...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.08.009
更新日期：2019-01-01 00:00:00
abstract：:In a review of the current literature, we identified (1)H MRS studies of major depressive disorder (MDD) that examined the metabolites N-acetylaspartate (NAA), choline (Cho), myo-inositol (mI), glutamate/glutamine/gamma-aminobutyric acid-GABA (Glx), and creatine (Cr). Separate meta-analyses comparing adult and pediatr...
journal_title：Psychiatry research
pub_type： 杂志文章,meta分析
doi：10.1016/j.pscychresns.2005.12.004
更新日期：2006-06-30 00:00:00
abstract：:Bilateral electroconvulsive therapy (ECT) seizure threshold charge averaged 162.8 and 125.1 mC at 900 and 1150 mA, respectively (p<0.02), measured in randomized balanced order (N=18). Results are consistent with stimulus dose strongly depending on current besides charge, rather than charge alone. ECT stimuli of differ...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2011.12.046
更新日期：2012-06-30 00:00:00
abstract：:This study was designed to assess cognitive functioning in a clinical sample of adolescents with heterogeneous psychiatric diagnoses, with a specific focus on patients at clinical high risk (CHR) for psychosis. The sample comprised 22 patients identified at CHR for psychosis, 67 psychotic and 187 non-psychotic, non-CH...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.04.011
更新日期：2010-09-30 00:00:00
abstract：:Suicide rates vary among racel- and age-defined groups, yet little is known about how suicide risk factors differentially impact individual groups. This study assessed differential associations of socioeconomic status among age- and race-defined groups of suicide victims. A database containing demographic information ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.02.003
更新日期：2009-05-30 00:00:00
abstract：:The Morningness-Eveningness Questionnaire (MEQ) is among the most commonly used scales to measure chronotype. We aimed to evaluate psychometric properties and clinical correlates of MEQ in bipolar disorder. Patients with a clinical diagnosis of bipolar disorder (n = 53) answered questionnaires for chronotype (MEQ), mo...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.02.004
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:To examine the construct validity of the 9 item Traumatic Events Questionnaire (TEQ) and to evaluate the extent to which experiences of trauma assessed using the TEQ are associated with symptoms of psychiatric disorders among 3342 pregnant women in Lima, Peru. METHODS:Symptoms of depression were assessed usi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.08.016
更新日期：2017-11-01 00:00:00
abstract：:This study aimed to assess stigma and its sociodemographic and clinical correlates among patients with bipolar disorder while in remission. 185 patients currently in remission were assessed on Internalized Stigma of Mental Illness Scale (ISMIS) for internalized stigma, Explanatory Model Interview Catalogue Stigma Scal...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.07.012
更新日期：2016-10-30 00:00:00
abstract：:Cognitive dysfunction is a chronically disabling feature of schizophrenia, associated with limits in obtaining rehabilitation improvements. The purpose of this study is to assess the effectiveness of intensive computer-aided cognitive remediation treatment (CRT) added to a standard rehabilitation treatment (SRT), in e...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.psychres.2008.06.027
更新日期：2009-10-30 00:00:00
abstract：:A review of medical charts over a 1-year period was carried out in a population of 213 Taiwanese psychiatric inpatients that included 106 patients with schizophrenia. In subgroup analyses within the group of patients with schizophrenia, no significant differences in serum cholesterol levels were found between paranoid...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(00)00206-7
更新日期：2000-10-30 00:00:00
abstract：:There is a strong link between personality disorders (PDs) and aggression. This is reflected in high prevalence rates of PD diagnoses in forensic samples, and in several diagnostic criteria of PDs directly referring to elevated levels of aggression. Aggression can stem from two distinct types of motivation; reactive o...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.psychres.2015.07.052
更新日期：2015-09-30 00:00:00
abstract：:The diagnosis of patients suffering from both anxiety and depression is complex due to mixed effects of the two disorders. This complexity has hardened the task to find an adapted treatment for these patients. Consequently, several instruments, known as depression anxiety scales, have been developed and are now used i...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.02.074
更新日期：2019-04-01 00:00:00
abstract：:Although social skills training (SST) is an effective approach for improving social skills for schizophrenia, the motivational deficit attenuates its efficacy. Virtual reality (VR) applications have allowed individuals with mental disabilities to enhance their motivation for rehabilitation. We compared SST using VR ro...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2011.04.003
更新日期：2011-09-30 00:00:00
abstract：:Defensive responding in schizotypy questionnaires might depend on context. Students completed a schizotypy questionnaire in a "psychiatric" context or a "creativity" context. Positive, but not negative, schizotypy scores were lower in the psychiatry than in the creativity group, but findings applied mainly to male par...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2005.06.006
更新日期：2005-09-15 00:00:00
abstract：:A recent genome-wide association study (GWAS) for major depressive disorder (MDD) in Chinese women identified a single-nucleotide polymorphism (SNP), rs12415800, near the Sirtuin1 (SIRT1) gene as one of the top candidate loci. However, no study has shown a genetic association between SIRT1 and completed suicide, which...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.06.002
更新日期：2019-08-01 00:00:00
abstract：:Reduction of volume and neuronal number has been found in several association nuclei of the thalamus in schizophrenic subjects. Recent evidence suggests that schizophrenic patients exhibit abnormalities in early visual processing and that many of the observed perceptual deficits are consistent with dysfunction of the ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.11.003
更新日期：2007-05-30 00:00:00
abstract：:The Cocaine Craving Questionnaire was administered to 205 cocaine addicts. A 6/5 cut-off corresponded to the scale's best performance. Reliability was 0.803. Receiver Operating Characteristic analysis resulted in an area under the curve of 0.7199 +/- 0.0384, and dimensionality resulted in a three-factor solution. The ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.01.010
更新日期：2006-06-15 00:00:00
abstract：:Platelet serotonin levels were measured in several psychiatric disorders to determine whether they distinguish among major depressive disorder (one or more depressive episodes and no manic episodes), dysthymic disorder (depressive neurosis), and schizophrenic and paranoid disorders. Serotonin levels in 141 subjects we...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(84)90056-8
更新日期：1984-10-01 00:00:00
abstract：:In this study, we investigated whether polymorphisms of the dopamine D4 receptor (DRD4) gene were associated with psychotic symptomatology rather than with a unique diagnosis such as schizophrenia. A number of association studies between the DRD4 gene 48 bp-VNTR polymorphism at exon 3 and psychotic disorders have been...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.12.011
更新日期：2007-12-03 00:00:00
abstract：:In a previous study, we reported a nonrandom segregation between schizophrenia and the pseudoautosomal locus DXYS14 in a sample of 33 sibships. That study has been extended by the addition of 16 new sibships from 16 different families. Data from six other loci of the pseudoautosomal region and of the immediately adjac...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(94)90083-3
更新日期：1994-05-01 00:00:00
abstract：:In many countries fewer than 20% of individuals with schizophrenia receive depot antipsychotic medication. Frequently stated reasons are psychiatrist's, patient's and relative's objections to depot treatment. This is the first study that directly compares the attitudes to depot antipsychotics of psychiatrists, patient...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.11.003
更新日期：2010-01-30 00:00:00
abstract：:Ninety-five patients hospitalized for acute psychosis were reviewed with respect to hallucinogen use and family history of mental illness. Sixty-three percent of admissions had used hallucinogens to some degree within 3 years of the index admission. Drug users were predominantly male, although no age or diagnostic dif...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90030-6
更新日期：1983-06-01 00:00:00
abstract：:There are no articles in the international psychiatric literature reporting subclinical visual system disorders in depressed patients, although a disturbance of circadian rhythms is one of the prominent theories of the etiopathogenesis of depression. Fifty patients aged 21-60 years suffering from major depression acco...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00097-0
更新日期：2003-06-15 00:00:00
abstract：:Affective touch is important for social interaction within families and groups and there is evidence that unmyelinated C tactile fibers are involved in this process. Individuals with autism spectrum disorders show alterations in the perception and processing of affective touch. sThus, we hypothesized that affective to...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.09.011
更新日期：2016-11-30 00:00:00
abstract：:The main goal in the treatment of major depressive disorder (MDD) is to achieve remission, defined as the resolution of symptoms and the return to normal levels of functionality. However, the clinical assessment of remission is usually merely based on scores of symptomatic rating scales. One of the most widely used sc...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.psychres.2010.06.023
更新日期：2011-03-30 00:00:00
abstract：:The mineralocorticoid receptor (Nr3c2) has received increased attention as an important stress-related gene. Here, we sought to uncover candidate genes regulating the expression of Nr3c2. Using a genetical genomics approach, we identified a significant trans-regulated expression quantitative trait locus (eQTL) at Chro...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112760
更新日期：2020-01-07 00:00:00
abstract：:The current study was designed to explore the specific relationship between neurologic soft signs (NSSs) and characteristics of antisocial personality traits in adolescents, and to investigate particular NSSs linked to certain brain regions in adolescents with antisocial personality traits. The research was conducted ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.04.023
更新日期：2016-09-30 00:00:00
abstract：:Medication non-adherence is one of the major obstacles to recovery in first-episode psychosis (FEP). This study aimed to identify the predictors and rates of medication non-adherence in the first and second year after the start of treatment (baseline) in urban Chinese FEP patients. Relevant information on medication n...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.04.047
更新日期：2015-08-30 00:00:00
abstract：:Abnormalities of electroencephalographic (EEG) coherence in schizophrenia are thought to reflect functional disconnections between different brain regions associated with the onset of this disease. To clarify whether these abnormalities change in a symptom-dependent manner in individual patients, we analyzed the coher...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2005.05.020
更新日期：2007-01-15 00:00:00
