Abstract：
:Persistent infection with Herpes Simplex viruses (HSV) and other brain infections is consistently associated with cognitive impairment. These infections can also affect sleep. Thus, sleep abnormalities could explain the cognitive dysfunction. We investigated the association between sleep variables and persistent HSV-1, HSV-2, cytomegalovirus (CMV) and Toxoplasma gondii (Tox) infections. Sleep data were collected from older adults with or without insomnia (N = 311, total); a subset completed polysomnographic and actigraphy studies (N = 145). No significant associations were found between the infections and insomnia or the remaining sleep variables following corrections for multiple comparisons. Sleep dysfunction is unlikely to explain the infection-related cognitive dysfunction.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Meshreky KM,Wood J,Chowdari KV,Hall MH,Wilckens KA,Yolken R,Buysse DJ,Nimgaonkar VLdoi
10.1016/j.psychres.2019.112502subject
Has Abstractpub_date
2019-10-01 00:00:00pages
112502eissn
0165-1781issn
1872-7123pii
S0165-1781(19)30288-4journal_volume
280pub_type
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