Abstract：
:Cognitive dysfunction is a chronically disabling feature of schizophrenia, associated with limits in obtaining rehabilitation improvements. The purpose of this study is to assess the effectiveness of intensive computer-aided cognitive remediation treatment (CRT) added to a standard rehabilitation treatment (SRT), in enhancing neuropsychological performances and daily functioning in patients with schizophrenia. A 12-week, randomized, controlled, single-blind trial of neurocognitive remediation was carried out on 86 patients with clinically stabilized DSM-IV schizophrenia. Patients were assessed on cognitive and daily functioning before and after either CRT or placebo training that had been added to their SRT. After 3 months the repeated measure ANOVA showed a significant time x treatment interaction for executive function and attention performances and in daily functioning assessment in favour of patients in the SRT+CRT treatment. Results confirmed that cognitive remediation added to the SRT of schizophrenia enhanced its neuropsychological effects and increased the effects of a long-term rehabilitation programme in terms of functional outcomes.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Cavallaro R,Anselmetti S,Poletti S,Bechi M,Ermoli E,Cocchi F,Stratta P,Vita A,Rossi A,Smeraldi Edoi
10.1016/j.psychres.2008.06.027subject
Has Abstractpub_date
2009-10-30 00:00:00pages
191-6issue
3eissn
0165-1781issn
1872-7123pii
S0165-1781(08)00197-2journal_volume
169pub_type
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