Abstract：
:We compared regional cerebral blood flow (rCBF) in 15 patients with DSM IIIR obsessive-compulsive disorder (OCD), 15 patients with DSM IIIR panic disorder and 15 healthy controls matched for age, sex and hand preference, using uptake of technetium-99m-D,L-hexamethyl-propylene amine oxime (99mTc HMPAO), on single photon emission computerised tomography (SPECT). Caudate rCBF was significantly reduced in OCD patients compared to healthy subjects and panic disorder patients. When four patients were excluded from each group, right caudate rCBF remained significantly lower in OCD patients than in panic disorder patients or healthy subjects. The data suggest functional involvement of the right caudate nucleus is present in OCD.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Lucey JV,Costa DC,Busatto G,Pilowsky LS,Marks IM,Ell PJ,Kerwin RWdoi
10.1016/s0925-4927(96)03017-xsubject
Has Abstractpub_date
1997-03-14 00:00:00pages
25-33issue
1eissn
0165-1781issn
1872-7123journal_volume
74pub_type
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