Abstract:
:Plasma free homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) were measured before drug treatment in 29 patients diagnosed as having major depression with melancholia and in 18 control subjects. Plasma HVA was significantly elevated in the total group of female melancholic patients when compared with female controls or male melancholics. Most female patients with psychotic melancholia had elevated HVA levels. These differences were not found in male patients. No significant differences were found for plasma MHPG.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Devanand DP,Bowers MB Jr,Hoffman FJ Jr,Nelson JCdoi
10.1016/0165-1781(85)90033-2subject
Has Abstractpub_date
1985-05-01 00:00:00pages
1-4issue
1eissn
0165-1781issn
1872-7123pii
0165-1781(85)90033-2journal_volume
15pub_type
杂志文章abstract::Electroconvulsive therapy (ECT) is effective in treatment-resistant depression (TRD). It may act through intracellular process modulation, but its exact mechanism is still unknown. Animal research supports a neurotrophic effect for ECT. We aimed to investigate the association between changes in serum brain-derived neu...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.009
更新日期:2015-06-30 00:00:00
abstract::A cohort of acutely ill, hospitalized patients with chronic psychotic disorders participated in a study of a manualized community reintegration skills training program. Initial data analyses revealed that skill levels improved significantly over the course of treatment, and that higher post-training skill levels were ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(96)03013-2
更新日期:1997-03-24 00:00:00
abstract::Social cognitive deficits in schizophrenia are well documented and related to functional outcome. Current social cognition measures are often not psychometrically validated, too heterogeneous for standardization, and focus principally on one domain of social cognition rather than the simultaneous activation of multipl...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.03.014
更新日期:2014-07-30 00:00:00
abstract::There have been conflicting findings as to whether the P3 brain potential to targets in oddball tasks is reduced in depressed patients. The P3 to novel distracter stimuli in a three-stimulus oddball task has a more frontocentral topography than P3 to targets and is associated with different cognitive operations and ne...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.10.023
更新日期:2009-12-30 00:00:00
abstract::Controversy exists regarding the association of age with postdexamethasone serum cortisol levels. We evaluated this relationship in 95 patients with major depressive disorder and 49 healthy controls. Age and 8 a.m. postdexamethasone cortisol levels were not correlated among the healthy controls, but were positively as...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90036-2
更新日期:1984-11-01 00:00:00
abstract::The current study was designed to explore the specific relationship between neurologic soft signs (NSSs) and characteristics of antisocial personality traits in adolescents, and to investigate particular NSSs linked to certain brain regions in adolescents with antisocial personality traits. The research was conducted ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.04.023
更新日期:2016-09-30 00:00:00
abstract::Impaired visual integration is well documented in schizophrenia and related to functional outcomes. However, it is unclear if this deficit is specific to schizophrenia, or characteristic of psychosis more broadly. To address this question, this study used a Bayesian model comparison approach to examine the evidence of...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.061
更新日期:2018-07-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(96)02888-0
更新日期:1996-09-27 00:00:00
abstract::The current study was the first one to reveal the contribution of DRD3 methylation to the risk of different (SCZ) subtypes. This study comprised a total of 30 paranoid (15 males and 15 females) and 29 undifferentiated (15 males and 14 females) SCZ patients and 26 age- and gender-matched controls. Our results showed a ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.08.032
更新日期:2014-12-30 00:00:00
abstract::We performed spectral analysis on the QRS complex of the electrocardiogram obtained using standard limb leads, sampled at 500 Hz with 12 bit precision in 20 normal subjects and 15 patients with panic disorder. We divided the frequency range of the QRS into two bands based on spectral patterns before and after the post...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(96)02998-8
更新日期:1997-02-07 00:00:00
abstract::Treatment in early intervention services (EIS) seems superior to treatment as usual on several outcomes, but the extent of heterogeneity in response is unclear. In this study, treatment response trajectories up to 2 years in first-episode psychosis (FEP) patients enrolled in an Italian early intervention service (EIS)...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113200
更新日期:2020-09-01 00:00:00
abstract::The Unified Biosocial Theory of Personality developed by Cloninger has been applied in different cultures. Distribution by age and sex of the Temperament and Character Inventory (TCI) dimensions were assessed cross-culturally for samples in Spain and the USA. Three non-clinical samples were included: i) 404 participan...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.07.021
更新日期:2011-04-30 00:00:00
abstract::Although the fear of being scrutinized by others in a social context is a key symptom in social anxiety disorder (SAD), the neural processes underlying the perception of scrutiny have not previously been studied by functional magnetic resonance imaging (fMRI). We used fMRI to map brain activation during a perception-o...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.10.008
更新日期:2012-06-30 00:00:00
abstract::Major depressive disorder is associated with lower medial prefrontal cortex volumes. The role that gender might play in moderating this relationship and what particular medial prefrontal cortex subregion(s) might be implicated is unclear. Magnetic resonance imaging was used to assess dorsal, ventral, and anterior cing...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.06.005
更新日期:2015-08-30 00:00:00
abstract::This study aimed to evaluate the efficacy of a diet and exercise lifestyle intervention on mental health outcomes for patients currently being treated for depression and/or anxiety in primary care. Patients (n=119) referred by general practitioners to the 12-week randomised controlled trial were assigned to either an ...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2015.10.001
更新日期:2015-12-15 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.095
更新日期:2018-11-01 00:00:00
abstract::Transdiagnostic approach has a long history in neuroimaging, predating its recent ascendance as a paradigm for new psychiatric nosology. Various psychiatric disorders have been compared for commonalities and differences in neuroanatomical features and activation patterns, with different aims and rationales. This revie...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.01.026
更新日期:2019-07-01 00:00:00
abstract::The present study continues the examination of the personality styles in normal populations that have been described in the clinical literature. Earlier work has focused on behavioral, attitudinal, and cognitive components of the personality styles. The present study extends our exploration of the cognitive domain by ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90112-9
更新日期:1983-10-01 00:00:00
abstract::There is a need for theoretically-based research on the motivational processes linked to the adoption and maintenance of an active lifestyle in people with affective disorders. Within the Self-Determination Theory (SDT) framework, we investigated the SDT tenets in people with major depressive disorder or bipolar disor...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2015.04.021
更新日期:2015-07-30 00:00:00
abstract::This study examined neuroanatomical differences between male schizophrenic patients with a family history of psychosis (n = 16) and those without such a history (n = 15). Intracranial area, cerebral area, ventricular size, and cortical atrophy were assessed using magnetic resonance imaging (MRI). Third ventricular enl...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0925-4927(91)90028-o
更新日期:1991-05-01 00:00:00
abstract::A variety of studies were addressed to differentiate responders and non-responders to substitution treatment among heroin dependent patients, without conclusive findings. In particular, preliminary pharmacogenetic findings have been reported to predict treatment effectiveness in mental health and substance use disorde...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.11.001
更新日期:2014-01-30 00:00:00
abstract::A family history method for DSM-III anxiety and personality disorders (FHPD) was validated by direct interview of 182 relatives. The categories of "any anxiety disorder," "panic disorder," and "any personality disorder" achieved sensitivities and specificities equivalent to currently accepted psychiatric family histor...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90067-4
更新日期:1988-11-01 00:00:00
abstract::We examined the associations of current alcohol consumption with brain morphometric measures in a healthy, community-dwelling cohort. Cranial T1-weighted 3D-structural MRI scans were obtain in 383 adults (men=211) aged 60-64 years, randomly selected form the larger PATH Through Life study. Voxel-based morphometric ana...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2007.08.009
更新日期:2008-05-30 00:00:00
abstract::Childhood experiences, personality, and polyunsaturated essential fatty acid (PUFA) composition have all been shown to affect the likelihood of depressive symptoms. Few studies have addressed relationships between these factors in their influence on the occurrence or course of depressive symptoms. The following analys...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.06.036
更新日期:2017-10-01 00:00:00
abstract::Plasma levels of homovanillic acid (HVA), a dopamine metabolite, were examined in 19 psychiatric inpatients during maintenance treatment on neuroleptic medications. A significant positive correlation was found between the level of HVA and the severity of tardive dyskinesia (TD) in these patients. Seven patients had th...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90046-x
更新日期:1983-07-01 00:00:00
abstract::Platelet monoamine oxidase (MAO) activity appears to be correlated to certain diagnostic subgroups and symptom patterns. A group of criminal offenders hospitalized for forensic psychiatric assessment were studied. Male nurses and construction workers were used as controls. Patients who were diagnosed as psychopaths ac...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(85)90125-8
更新日期:1985-12-01 00:00:00
abstract::Considerable evidence suggests that there is a relationship between pathologic aggressive behavior and low cerebrospinal fluid (CSF) concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in both humans and non-human primates. The purpose of this investigation is to examine the relationship bet...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(99)00022-0
更新日期:1999-04-19 00:00:00
abstract::Bipolar disorder is prone to being overlooked because its diagnosis is more often based on retrospective report than cross-sectional assessment. Recommendations for improving the detection of bipolar disorder include the use of screening questionnaires. The Mood Disorder Questionnaire (MDQ) is the most widely studied ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.06.025
更新日期:2011-02-28 00:00:00
abstract::This study examined quantitative measures of sleep electroencephalogram (EEG) and phasic rapid eye movements (REM) as correlates of remission and recovery in depressed patients. To address correlates of remission, pre-treatment EEG sleep studies were examined in 130 women outpatients with major depressive disorder tre...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-1781(01)00270-0
更新日期:2001-08-05 00:00:00
abstract::The World Health Organization ranks obsessive compulsive disorder (OCD) among the leading causes of worldwide medical disability. Affecting approximately 3% of the population, OCD, with its damaging effect on psychosocial function, is among the most severe and impairing of mental disorders. In Diagnostic and Statistic...
journal_title:Psychiatry research
pub_type:
doi:10.1016/j.psychres.2014.12.002
更新日期:2015-05-30 00:00:00