Family history and brain morphology in schizophrenia: an MRI study.

Abstract:

:This study examined neuroanatomical differences between male schizophrenic patients with a family history of psychosis (n = 16) and those without such a history (n = 15). Intracranial area, cerebral area, ventricular size, and cortical atrophy were assessed using magnetic resonance imaging (MRI). Third ventricular enlargement was more prevalent in patients than controls (n = 15). Familial and nonfamilial patients differed significantly. Reduced cranial and cerebral areas without ventricular enlargement characterized familial patients, whereas nonfamilial patients showed marked lateral ventricular enlargement without a reduction in cranial/cerebral size.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Schwarzkopf SB,Nasrallah HA,Olson SC,Bogerts B,McLaughlin JA,Mitra T

doi

10.1016/0925-4927(91)90028-o

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

49-60

issue

1

eissn

0165-1781

issn

1872-7123

pii

0165-1781(91)90144-E

journal_volume

40

pub_type

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