Assessment of water use for estimating exposure to tap water contaminants.

abstract：BACKGROUND:Studies suggest that phthalate exposures may adversely affect child respiratory health. OBJECTIVES:We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEH...

journal_title：Environmental health perspectives

authors： Whyatt RM,Perzanowski MS,Just AC,Rundle AG,Donohue KM,Calafat AM,Hoepner LA,Perera FP,Miller RL

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Lead exposure is associated with elevated blood pressure during pregnancy; however, the magnitude of this relationship at low exposure levels is unclear. OBJECTIVES:Our goal was to determine the association between low-level lead exposure and blood pressure during late pregnancy. METHODS:We collected admis...

journal_title：Environmental health perspectives

authors： Wells EM,Navas-Acien A,Herbstman JB,Apelberg BJ,Silbergeld EK,Caldwell KL,Jones RL,Halden RU,Witter FR,Goldman LR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue. OBJECTIVES:We aimed to examine the relationship between environmental cadmium exposure and dental caries in children 6-12 years of age. METHODS:We analyzed c...

journal_title：Environmental health perspectives

authors： Arora M,Weuve J,Schwartz J,Wright RO

更新日期：2008-06-01 00:00:00

abstract：:The accumulation of genetic damage in the forms of activated proto-oncogenes and inactivated tumor-suppressor genes is the driving force in the evolution of a normal cell to a malignant cell. For example, both the activation of ras oncogenes and the inactivation of several suppressor genes, including p53, have been ob...

journal_title：Environmental health perspectives

authors： Anderson MW,Reynolds SH,You M,Maronpot RM

更新日期：1992-11-01 00:00:00

abstract：:Biological monitoring of genotoxic hazard in the rubber industry was performed in 19 male workers and 20 age-matched controls in a local health unit in northern Italy. Peripheral blood lymphocytes were analyzed for the presence of DNA damage (single-cell microgel-electrophoresis, or comet assay) and for cytogenetic pa...

journal_title：Environmental health perspectives

authors： Moretti M,Villarini M,Scassellati-Sforzolini G,Monarca S,Libraro M,Fatigoni C,Donato F,Leonardis C,Perego L

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:The National Environmental Policy Act and related state laws require many public agencies to analyze and disclose potentially significant environmental effects of agency actions, including effects on human health. In this paper we review the purpose and procedures of environmental impact assessment (EIA), ex...

journal_title：Environmental health perspectives

authors： Bhatia R,Wernham A

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:A growing body of evidence indicates a relationship between household indoor air pollution from cooking fires and adverse neonatal outcomes, such as low birth weight (LBW), in resource-poor countries. OBJECTIVE:We examined the effect of reduced wood smoke exposure in pregnancy on LBW of Guatemalan infants i...

journal_title：Environmental health perspectives

authors： Thompson LM,Bruce N,Eskenazi B,Diaz A,Pope D,Smith KR

更新日期：2011-10-01 00:00:00

abstract：:Much public health research has been directed to studies of cancer risks due to chemical agents. Recently, increasing attention has been given to adverse reproductive outcomes as another, shorter-term biologic indicator of public health impact. Further, several low-level ubiquitous physical agents have been implicated...

journal_title：Environmental health perspectives

authors： Meyer RE,Aldrich TE,Easterly CE

更新日期：1989-05-01 00:00:00

abstract：:This paper summarizes the clinical phenomenology of multiple chemical sensitivity (MCS), outlines the concepts and evidence for the olfactory-limbic, neural sensitization model for MCS, and discusses experimental design implications of the model for exposure-related research. Neural sensitization is the progressive am...

journal_title：Environmental health perspectives

authors： Bell IR,Schwartz GE,Baldwin CM,Hardin EE,Klimas NG,Kline JP,Patarca R,Song ZY

更新日期：1997-03-01 00:00:00

abstract：:Elucidation of the role of vinyl chloride metabolites in the various reaction sequences which comprise the metabolic pathway, including the interaction of reactive metabolities with some purine and pyrimidine residues of target-organ DNA, provides some explanation for the (oncogenic) properties associated with the ori...

journal_title：Environmental health perspectives

authors： Hathway DE

更新日期：1977-12-01 00:00:00

abstract：:In August 1997 we performed a follow-up survey of 146 lead-poisoned children from a community near a previously active auto battery recycling smelter in Haina near Santo Domingo, Dominican Republic. Our follow-up survey confirmed a severe incidence of elevated blood lead (BPb) and erythrocyte protoporphyrin/zinc proto...

journal_title：Environmental health perspectives

authors： Kaul B,Sandhu RS,Depratt C,Reyes F

更新日期：1999-11-01 00:00:00

abstract：:We have witnessed a tremendous increase in our knowledge of the molecular and biochemical mechanisms which underly the activities of the nervous system. Such knowledge is essential in order to determine the basic mechanisms involved in neurotoxic events. An overview of how neurotoxins could conceivably interfere with ...

journal_title：Environmental health perspectives

authors： Damstra T

更新日期：1978-10-01 00:00:00

abstract：:A patient with massive exposure to tetrachloroethylene fumes presented with coma and severe pulmonary edema. Sequential blood gases, chest x-rays, and clinical findings showed dramatic improvement with conventional but aggressive management and the patient recovered completely. There was no evidence of permanent renal...

journal_title：Environmental health perspectives

authors： Patel R,Janakiraman N,Towne WD

更新日期：1977-12-01 00:00:00

abstract：:N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. De...

journal_title：Environmental health perspectives

authors： King CM,Glowinski IB

更新日期：1983-03-01 00:00:00

abstract：:Serious problems emerge when evaluating evidence on lead neurotoxicity in children. The extent of these problems and ways to control them were explored in a study of 1291 children from the first class in the schools of Aarhus municipality, Denmark. The lead retention in circumpulpal dentin in shed deciduous teeth was ...

journal_title：Environmental health perspectives

authors： Grandjean P,Lyngbye T,Hansen ON

更新日期：1991-08-01 00:00:00

abstract：:Epidemiological studies report a small but positive association between short-term increases in airborne particulate matter and small increases in morbidity and mortality from respiratory and cardiovascular disease in urban areas. However, the lack of a mechanistic explanation to link particle exposure and human healt...

journal_title：Environmental health perspectives

authors： Holian A,Hamilton RF Jr,Morandi MT,Brown SD,Li L

更新日期：1998-03-01 00:00:00

abstract：:Environmental health is a subject that has only relatively recently become prominent in the social consciousness. Even as its significance becomes known, finding ways to integrate the subject into education for primary and secondary students is difficult because of federal testing requirements under the No Child Left ...

journal_title：Environmental health perspectives

authors： Brown VJ

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. OBJECTIVES:This study was designed to evaluate whether pren...

journal_title：Environmental health perspectives

authors： Xia W,Du X,Zheng T,Zhang B,Li Y,Bassig BA,Zhou A,Wang Y,Xiong C,Li Z,Yao Y,Hu J,Zhou Y,Liu J,Xue W,Ma Y,Pan X,Peng Y,Xu S

更新日期：2016-01-01 00:00:00

abstract：:Because of their history of widespread use in the United States and unknown long-term health effects, organophosphate pesticides (OPs) are being considered as a chemical class of interest in planning for the National Children's Study, a longitudinal study of children's environmental health. The availability and approp...

journal_title：Environmental health perspectives

authors： Wessels D,Barr DB,Mendola P

更新日期：2003-12-01 00:00:00

abstract：:A case control study of drinking water treatment practices and female cancer mortality was conducted in Wisconsin. Cancer deaths for 1972-1977 from 28 Wisconsin counties and noncancer deaths matched to cancer deaths on age, year of death and county of residence, were compared for characteristics of drinking water supp...

journal_title：Environmental health perspectives

authors： Kanarek MS,Young TB

更新日期：1982-12-01 00:00:00

abstract：:Epidemiologic studies long have played a role in the understanding of the effects of the general environment and various occupational exposures on the occurrence of acute and chronic diseases of the lung. This article is an overview of epidemiologic study designs that have particular relevance to studies of environmen...

journal_title：Environmental health perspectives

authors： Tager IB

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Childhood lead exposure has been associated with growth delay. However, the association between blood lead levels (BLLs) and insulin-like growth factor 1 (IGF-1) has not been characterized in a large cohort with low-level lead exposure. METHODS:We recruited 394 boys 8-9 years of age from an industrial Russi...

journal_title：Environmental health perspectives

authors： Fleisch AF,Burns JS,Williams PL,Lee MM,Sergeyev O,Korrick SA,Hauser R

更新日期：2013-07-01 00:00:00

abstract：:Historical aerial applications of the insecticide Matacil 1.8D provide an opportunity to look for potential effects of the endocrine disrupting compound 4-nonylphenol (4-NP) on Atlantic salmon (Salmo salar) populations. Matacil 1.8D contained the carbamate insecticide aminocarb, with 4-NP as primary solvent. Between 1...

journal_title：Environmental health perspectives

authors： Fairchild WL,Swansburg EO,Arsenault JT,Brown SB

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:According to the 2007 National Research Council report Toxicology for the Twenty-First Century, modern methods (e.g., "omics," in vitro assays, high-throughput testing, computational methods) will lead to the emergence of a new approach to toxicology. The Salmonella mammalian microsome mutagenicity assay has...

journal_title：Environmental health perspectives

authors： Claxton LD,Umbuzeiro Gde A,DeMarini DM

更新日期：2010-11-01 00:00:00

abstract：:In recent years there has been an increasing focus in environmental risk assessment on children as a potentially susceptible population. There also has been growing recognition of the need for a systematic approach for organizing, evaluating, and incorporating the available data on children's susceptibilities in risk ...

journal_title：Environmental health perspectives

authors： Daston G,Faustman E,Ginsberg G,Fenner-Crisp P,Olin S,Sonawane B,Bruckner J,Breslin W,McLaughlin TJ

更新日期：2004-02-01 00:00:00

abstract：:Nicotine and cigarette smoke extract show acute physiological effects: increasing tracheal pressure (PTR), pulmonary artery pressure (PPA), systemic blood pressure (PSYST), and left atrium pressure (PLA); and decreasing cardiac output (QAORTA) and blood flow to the left lower lobe (QLLL). In addition, cigarette smokin...

journal_title：Environmental health perspectives

authors： Kitamura S

更新日期：1987-06-01 00:00:00

abstract：:Mortality curves for groups of fasted male rats treated with single, oral doses of 1,1-dichloroethylene (1,1-DCE, vinylidene chloride) were not monotonically increasing sigmoids, but were complex with maxima or extended plateaus in the region of dose between 100 and 700 mg of 1,1-DCE/kg. The exact shape was a function...

journal_title：Environmental health perspectives

authors： Andersen ME,Jenkins LJ Jr

更新日期：1977-12-01 00:00:00

abstract：:Under a cooperative agreement between New York University and the Environmental Protection Agency, and in collaboration with the University of Sao Paulo (USP), a study is ongoing in Cubatao, Brazil, to try to establish exposure-response relationships on the impact of specific industrial effluents on respiratory functi...

journal_title：Environmental health perspectives

authors： Spektor DM,Hofmeister VA,Artaxo P,Brague JA,Echelar F,Nogueira DP,Hayes C,Thurston GD,Lippmann M

更新日期：1991-08-01 00:00:00

abstract：:In this article we summarize the results of a series of studies that measured the relative bioavailability (RBA) of lead in a variety of soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice a day for 15 days. Blood samples were col...

journal_title：Environmental health perspectives

authors： Casteel SW,Weis CP,Henningsen GM,Brattin WJ

更新日期：2006-08-01 00:00:00

abstract：:Asthma and lead poisoning are prevalent among urban children in the United States. Lead exposure may be associated with excessive production of immunoglobulin E, possibly increasing asthma risk and contributing to racial disparities. The objective of this study was to examine racial differences in the association of b...

journal_title：Environmental health perspectives

authors： Joseph CL,Havstad S,Ownby DR,Peterson EL,Maliarik M,McCabe MJ Jr,Barone C,Johnson CC

更新日期：2005-07-01 00:00:00