Abstract:
:Piwi-interacting RNAs (piRNAs) were reported in 2006 as a novel class of small non-coding RNAs associated with Piwi proteins of the Argonaute/Piwi family. Recent studies have revealed not only the biogenesis of piRNAs and their roles in transposon silencing, but also the function of the Piwi-piRNA pathway in epigenetic and post-transcriptional regulation of gene expression. In addition, the function of this pathway in somatic cells has also been more systematically characterized. The new findings reveal the Piwi-piRNA pathway as a more general mechanism of gene regulation.
journal_name
Curr Opin Cell Bioljournal_title
Current opinion in cell biologyauthors
Peng JC,Lin Hdoi
10.1016/j.ceb.2013.01.010subject
Has Abstractpub_date
2013-04-01 00:00:00pages
190-4issue
2eissn
0955-0674issn
1879-0410pii
S0955-0674(13)00021-5journal_volume
25pub_type
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journal_title:Current opinion in cell biology
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journal_title:Current opinion in cell biology
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journal_title:Current opinion in cell biology
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journal_title:Current opinion in cell biology
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journal_title:Current opinion in cell biology
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