Prognostic value of serum CA9 in patients with metastatic clear cell renal cell carcinoma under targeted therapy.

abstract：:The effect of Lonidamine (LND), an energolytic chemosensitizing agent, on the MDR (multidrug resistant) phenotype of a human breast cancer cell line (MCF-7) has been studied. The intracellular adriamycin (ADR) accumulation and distribution, the plasma membrane potential and the P170 glycoprotein phosphorylation, have ...

journal_title：Anticancer research

authors： Zupi G,Molinari A,D'Agnano I,Meschini S,Del Bufalo D,Matarrese P,Candiloro A,Calcabrini A,Citro G,Arancia G

更新日期：1995-11-01 00:00:00

abstract：:Cases with deletion of part of the long arm of chromosome 5 (5q-) and a myeloid hemopoietic disorder show a marked female preponderance. We analysed the female preponderance of 328 published cases of myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). MDS without clinical or cytogenetic progression shows ...

journal_title：Anticancer research

authors： Pedersen B

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:The possibilities and limitations of computer tomography (CT) examination for detecting primary gastric cancer tumors have been poorly understood. The aim of the present study was to evaluate the pre-operative assessment of gastric cancer tumors using 32-multidetector row-CT. PATIENTS AND METHODS:A prospect...

journal_title：Anticancer research

authors： Kikuchi S,Futawatari N,Sakuramoto S,Watanabe M,Kubota K,Sasaki M,Murata K,Kida M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Prognosis of renal cell carcinoma (RCC) differs within the same stage and grade. Our aim was to investigate the incidence of COX-2 in primary RCC tumors at different stages according to the occurrence of metastasis, and the impact of this biomarker on the survival of RCC patients. PATIENTS AND METHODS:The c...

journal_title：Anticancer research

authors： Kankuri-Tammilehto MK,Söderström KO,Pelliniemi TT,Vahlberg T,Pyrhönen SO,Salminen EK

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Adverse outcomes in breast cancer patients treated with recombinant human erythropoietin (rhEpo) have been linked to the expression of Epo-receptors (EpoR) in cancer cells, although limited data on the clinical significance of these observations are available. PATIENTS AND METHODS:Tissue samples from 107 pa...

journal_title：Anticancer research

authors： Volgger B,Kurz K,Zöschg K,Theurl I,Ciresa-König A,Marth C,Weiss G

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:It has recently been reported that sulindac has an apoptotic effect on KYN-2 cells, an undifferentiated hepatoma cell line. The present work investigates whether sulindac also has an apoptotic effect on well-differentiated hepatoma cells and what its potential mechanism might be. MATERIALS AND METHODS:Hep G...

journal_title：Anticancer research

authors： Liu JJ,Wang JY,Hertervig E,Nilsson A,Duan RD

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Ethanol injection is widely used in liposome preparation. However, the parameters determining particle size distribution of the liposomal preparation has not been fully defined. MATERIALS AND METHODS:A syringe pump-driven microfluidic injection device was used to produce liposomes under different conditions...

journal_title：Anticancer research

authors： Pradhan P,Guan J,Lu D,Wang PG,Lee LJ,Lee RJ

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the fifth most common cancer in Africa, with significant differences in incidence, biology and clinical behavior from other populations. MATERIALS AND METHODS:We studied prevalence and clinicopathological features of microsatellite instability (MSI) and young onset CRC in 83 archi...

journal_title：Anticancer research

authors： Irabor DO,Oluwasola OA,Ogunbiyi OJ,Ogun OG,Okolo CA,Melas M,Gruber SB,Shi C,Raskin L

更新日期：2017-05-01 00:00:00

abstract：:Concurrent cisplatin-based chemotherapy and radiotherapy (CCRT) plus brachytherapy is standard treatment for locally advanced cervical cancer. Platinum-based neoadjuvant chemotherapy (NACT) followed by radical hysterectomy has been proposed as an alternative approach, especially for patients with stage Ib2-IIb disease...

journal_title：Anticancer research

authors： Gadducci A,Cosio S

更新日期：2020-09-01 00:00:00

abstract：:We report two cases with small cell lung cancer (SCLC) receiving multicyclic dose-intensified chemotherapy (DI-CT) supported by autologous blood progenitor cell transplantation (ABPCT). Both cases were initially treated with cisplatin (CDDP), etoposide (ETP) and concurrent thoracic irradiation, however they had recurr...

journal_title：Anticancer research

authors： Fujimoto N,Ueoka H,Kiura K,Tabata M,Bessho A,Takata I,Sunami K,Hiramatsu Y,Ikeda K,Tanimoto M,Harada M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND/AIM:Few studies have examined postoperative CRP in esophageal cancer. We investigated the relationship between postoperative CRP values according to the postoperative period and prognosis in esophageal cancer. PATIENTS AND METHODS:We performed a retrospective cohort study including 187 patients who underwen...

journal_title：Anticancer research

authors： Katsurahara K,Shiozaki A,Fujiwara H,Konishi H,Kudou M,Shoda K,Arita T,Kosuga T,Morimura R,Murayama Y,Kuriu Y,Ikoma H,Kubota T,Nakanishi M,Okamoto K,Otsuji E

更新日期：2018-11-01 00:00:00

abstract：:Ovarian tumors of low malignant potential (LMPs) are intermediate between adenomas and ovarian carcinomas (OCs); however, whether an LMP is a precursor of OC or is a unique type of tumor that will not progress to OC is still controversial. To gain better insight into the relationship between LMP and OC, we compared pr...

journal_title：Anticancer research

authors： Nakayama K,Takebayashi Y,Hata K,Fujiwaki R,Iida K,Fukumoto M,Miyazaki K

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND/AIM:High-mobility group box 1 (HMGB1) is a nuclear DNA-binding protein that exerts a range of proinflammatory actions when it is secreted extracellularly. We hypothesized that HMGB1 released from damaged cells in pituitary apoplexy would exacerbate the neurological symptoms due to acute inflammation. PATIEN...

journal_title：Anticancer research

authors： Okuda T,Fujita M,Kato A

更新日期：2019-08-01 00:00:00

abstract：AIM:The aim of this study was to investigate if Linomide affects growth and spread of a rat liver tumour when given alone and in combination with interstitial laser thermotherapy (ILT). MATERIALS AND METHODS:Experiments were performed in Wistar rats using a dimethyl-hydrazine-induced adenocarcinoma implanted into the ...

journal_title：Anticancer research

authors： Ivarsson K,Sturesson C,Stenram U,Tranberg KG

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:It is essential that cytotoxic T-lymphocytes (CTLs) recognize tumor-associated antigens (TAAs) and exhibit antitumor effects in immunological responses for tumor rejection. However, only a few cases with oral squamous cell carcinoma (OSCC) have been studied for these antitumor mechanisms. We established a ca...

journal_title：Anticancer research

authors： Okamoto JY,Miyazaki A,Kobayashi JI,Miyamoto S,Sasaki T,Kanaseki T,Hirohashi Y,Torigoe T,Hiratsuka H

更新日期：2017-09-01 00:00:00

abstract：:Metastatic spread of malignancy is the primary cause of treatment failure and subsequent death in cancer patients. All cancers have the capability to metastasize, however, there are notable exceptions which rarely if ever metastasize. These include basal cell carcinoma, or cancers which are primarily locally invasive ...

journal_title：Anticancer research

authors： Kohn EC

更新日期：1993-11-01 00:00:00

abstract：:35 patients suffering from malignant stage III/IV glioma were enrolled into a prospectively randomized clinical trial. All patients were provided with standard oncologic treatment (neurosurgery, radiation, basic clinical care according to protocol and indication) and randomly divided into a) treatment group: receiving...

journal_title：Anticancer research

authors： Lenartz D,Stoffel B,Menzel J,Beuth J

更新日期：1996-11-01 00:00:00

abstract：:Antisense inhibition of the RelA subunit but not the NFKB1 subunit of NK-kappa B transcription factor results in a block of cellular adhesion and inhibition of tumor cell growth in vitro and in vivo. Studies aimed at dissecting the molecular mechanism of antisense relA action led to our identification of a kappa B-lik...

journal_title：Anticancer research

authors： Sharma HW,Higgins-Sochaski K,Perez JR,Narayanan R

更新日期：1995-09-01 00:00:00

abstract：:Methods for improving the estrogen receptor (ER) and progestin receptor (PgR) assay were studied. Using DCC procedure as the basis, the extraction and incubation of ER and PgR is more efficiently achieved by phosphate buffer as compared with water, tris and veronal buffers. The multiple extractions of hormone receptor...

journal_title：Anticancer research

authors： Chen YM,Rice RG,Vaughn CB

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Studies have recommended a 21-gene recurrence score (RS) to optimize adjuvant treatment for patients with early-stage breast cancer (EBC) with hormone receptor-positive (HR+) and human epidermal growth factor receptor-2 negative (HER2-) tumors. This study aimed to prospectively evaluate the impact of this RS...

journal_title：Anticancer research

authors： Zeng Y,Li Q,Qin T,Li S,Jin L,Wu J,Chen K,Deng H,Rao N,Liu Q,Su F,Jia W,Yao H

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND/AIM:4-methylumbelliferone (4-MU) has received considerable attention due to its potential for cancer treatment since it inhibits cell proliferation, migration and invasion. An increasing body of evidence suggests that extracellular matrix (e.g. hyaluronan) and nutrients (e.g. glucose) in the tumor microenvir...

journal_title：Anticancer research

authors： Wang R,Zhou W,Wang J,Liu Y,Chen Y,Jiang S,Luo X,Stupack DG,Luo N

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Live animal studies using an inoculation model of breast cancer indicate that anaesthetic drugs and techniques differentially affect cancer metastasis, inversely related to Natural Killer (NK) cell and T lymphocyte levels. Clinical histological studies demonstrate that the distribution of these immune cells ...

journal_title：Anticancer research

authors： Desmond F,McCormack J,Mulligan N,Stokes M,Buggy DJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The results of chemotherapy in patients with advanced, hormone-refractory prostate cancer (HRPC) have been disappointing. Mitoxantrone has been used in the past for palliation, but it does not prolong survival. It was recently demonstrated that docetaxel is able to improve median survival as compared to mito...

journal_title：Anticancer research

authors： Boehmer A,Anastasiadis AG,Feyerabend S,Nagele U,Kuczyk M,Schilling D,Corvin S,Merseburger AS,Stenzl A

更新日期：2005-11-01 00:00:00

abstract：:The characteristics of Nepalese breast cancer in relation to reproductive factors have not been studied. One hundred and nine Nepalese breast cancer patients were compared with 108 Japanese breast cancer patients and the expression of estrogen (ER) and progesterone receptor (PgR) was evaluated immunohistochemically in...

journal_title：Anticancer research

authors： Singh Y,Sayami P,Sayami G,Nakagawa H,Koreeda T,Hatano T,Tsubura A

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Despite the large use of bevabizumab in the treatment of primary tumors of the brain, there is only limited experience with brain metastases (BM) and no experience in the treatment of previously untreated secondary brain lesions. PATIENTS AND METHODS:We treated patients with BM, not suitable for local treat...

journal_title：Anticancer research

authors： Zustovich F,Ferro A,Lombardi G,Zagonel V,Fiduccia P,Farina P

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated patients undergoing salvage hysterectomy after brachytherapy (BT) following concomitant chemoradiation (CRT) for locally advanced cervical cancers (LACC), when residual disease was suspected. PATIENTS AND METHODS:From 2004 to 2013, 29 patients had a radical hysterectomy at the Gustave Rouss...

journal_title：Anticancer research

authors： Gosset M,Chargari C,Bentivegna E,Leary A,Genestie C,Maulard A,Morice P,Gouy S

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Because of clinicopathologic and genetic differences between left-sided colorectal cancer (LSCRC) and right-sided colon cancer (RSCC), cyclooxygenase-2(COX-2) and adenomatous polyposis coli (APC) expression may be of clinical relevance. MATERIALS AND METHODS:Clinicopathologic information for 72 primary colo...

journal_title：Anticancer research

authors： Nasir A,Lopez A,Boulware D,Malafa M,Coppola D

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To investigate the role of body composition and oxidative stress measured by total thiol groups (TTG) levels in prostate specimens of patients affected by benign prostatic hyperplasia (BPH) or prostate cancer (PCa). PATIENTS AND METHODS:From January 2011 to January 2013, a cohort of 150 consecutive male pati...

journal_title：Anticancer research

authors： Cimino S,Favilla V,Russo GI,Galvano F,Li Volti G,Barbagallo I,Giofrè SV,D'Orazio N,DI Rosa A,Madonia M,Morgia G

更新日期：2014-09-01 00:00:00

abstract：AIM:To investigate whether there is a difference in selenium levels before and after radiotherapy (RT) and to study the effects of serum selenium levels on RT-related toxicity in patients undergoing RT for head and neck cancer. PATIENTS AND METHODS:A population of 47 consecutive patients was enrolled in the study. RT ...

journal_title：Anticancer research

authors： Eroglu C,Unal D,Cetin A,Orhan O,Sivgin S,Oztürk A

更新日期：2012-08-01 00:00:00

abstract：:Angiosarcoma of the breast is a malignant tumour of vascular endothelial cells. It is a rare and difficult tumour to treat. The authors report a case of cutaneous radiation-associated angiosarcoma treated with paclitaxel chemotherapy. A few days after drug administration, bleeding of skin lesions was observed and the ...

journal_title：Anticancer research

authors： Tomasello L,Gardin G,Boccardo F

更新日期：2006-11-01 00:00:00