Abstract:
BACKGROUND:Oxidative stress has been implicated as a possible mechanism for adverse health effects associated with traffic emissions. We examined the association of an estimate of traffic emissions with blood biomarkers of antioxidant capacity (glutathione, glutathione peroxidase, trolox-equivalent antioxidant capacity) and oxidative damage (thiobarbituric acid-reactive substances (TBARS)) among 1810 healthy women, randomly selected from Erie and Niagara Counties in Western New York. METHODS:A geographic traffic emission and meteorological dispersion model was used to estimate annual polycyclic aromatic hydrocarbon (PAH) exposure from traffic emissions for each woman based on her residence at the time of study. Associations of traffic-related PAH exposure with measures of oxidative stress and antioxidant capacity were examined in multiple regression analyses with adjustment for potential confounders. RESULTS:Higher traffic-related PAH exposure was associated with decreased glutathione and increased glutathione peroxidase. Stronger associations between traffic-related PAH exposure and levels of glutathione and glutathione peroxidase were suggested among nonsmoking women without secondhand smoke exposure, especially among premenopausal nonsmoking women. Associations were also stronger for measurements made in warmer months. CONCLUSIONS:These findings suggest that PAHs or other components of traffic emissions may impact anti-oxidative capacity among healthy women, particularly premenopausal non-smokers without secondhand smoke exposure.
journal_name
Environ Resjournal_title
Environmental researchauthors
Li Y,Nie J,Beyea J,Rudra CB,Browne RW,Bonner MR,Mu L,Trevisan M,Freudenheim JLdoi
10.1016/j.envres.2012.10.003subject
Has Abstractpub_date
2013-02-01 00:00:00pages
31-8eissn
0013-9351issn
1096-0953pii
S0013-9351(12)00286-1journal_volume
121pub_type
杂志文章abstract:OBJECTIVE:Longitudinal studies on neurobehavioral development in relation to prenatal and postnatal exposure to phthalates in school-age children and adolescents are limited. We investigated the association of prenatal and childhood phthalate exposure with the development of behavioral syndromes in 8-14-year-old childr...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.02.029
更新日期:2019-05-01 00:00:00
abstract::A massive fire at a sulfur stockpile in the Western Cape Province of South Africa in December 1995 is estimated to have released over 14,000 t of sulfur dioxide (SO(2)) over a 20-h period. High and persistent winds greatly reduced the effectiveness of fire-fighting activities and increased the severity of impacts. Nea...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1999.3990
更新日期:1999-11-01 00:00:00
abstract::In 1925, Robert A. Kehoe enunciated a paradigm predicated upon categorical distinction between expectations and conjecture ("show me the data" mentality) from hard scientific facts on exposure outcomes. It led to a precedent-setting system of voluntary self-regulation by lead industry as a model for environmental cont...
journal_title:Environmental research
pub_type: 传,历史文章,杂志文章
doi:10.1006/enrs.1997.3808
更新日期:1998-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0013-9351(05)80186-0
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pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,meta分析
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更新日期:2018-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.03.029
更新日期:2016-07-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.04.007
更新日期:2012-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.08.003
更新日期:2008-05-01 00:00:00
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更新日期:2020-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1006/enrs.2002.4384
更新日期:2002-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-24 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1993.1039
更新日期:1993-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/s0013-9351(02)00009-9
更新日期:2003-05-01 00:00:00
abstract::The long-term drinking of water with a high content of inorganic arsenic can lead to Raynaud's phenomenon, acrocyanosis, and gangrene of the lower legs ("black foot disease"). We have measured the systolic blood pressure in the finger after local cooling in 47 workers from a copper smelter who were habitually exposed ...
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pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80070-6
更新日期:1986-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.envres.2014.12.027
更新日期:2015-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4240
更新日期:2001-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2005.04.007
更新日期:2006-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4082
更新日期:2000-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.09.002
更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.envres.2014.10.003
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,评审
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更新日期:2006-09-01 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2018-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109900
更新日期:2020-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90204-9
更新日期:1983-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.11.024
更新日期:2019-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.envres.2014.06.009
更新日期:2014-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.07.023
更新日期:2017-10-01 00:00:00