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Associations between ambient air pollution and daily mortality among persons with diabetes and cardiovascular disease.

Abstract：

BACKGROUND:Recent studies suggest that persons with diabetes and with cardiovascular disease may be at higher risk for the short-term effects of air pollution. We carried out this mortality time series study in Montreal, Quebec, Canada to confirm these observations and to determine whether diabetics who had other health conditions were also at higher risk of dying when air pollution increases. METHODS AND RESULTS:In one analysis, we related daily deaths from diabetes (using the underlying cause) to daily concentrations of particles and gaseous pollutants. In another analysis, we created subgroups by identifying subjects diagnosed 1 year before death with diabetes and other major health conditions from billing and prescription data from the universal Quebec Health Insurance Plan. The analysis made use of parametric log-linear Poisson models that were adjusted for long-term temporal trends and daily weather conditions. We found positive associations between most air pollutants and daily mortality from diabetes as well as among subjects diagnosed with diabetes 1 year before death. In the latter group of subjects, greater effects were found generally in the warm season and especially among subjects who had diabetes and who also had any cardiovascular disease, chronic coronary disease, and atherosclerosis. We did not find evidence of associations among persons who only had diabetes (i.e., did not also have cancer, cardiovascular disease, or lower respiratory disease). CONCLUSIONS:These data indicate that individuals with diabetes who also have cardiovascular disease may be susceptible to the short-term effects of air pollution.

journal_name

Environ Res

journal_title

Environmental research

authors

Goldberg MS,Burnett RT,Yale JF,Valois MF,Brook JR

doi

10.1016/j.envres.2005.04.007

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

255-67

issue

2

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(05)00064-2

journal_volume

100

pub_type

杂志文章

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