Abstract:
:Exponential increase in mobile phone uses, given rise to public concern regarding the alleged deleterious health hazards as a consequence of prolonged exposure. In 2018, the U.S. National toxicology program reported, two year toxicological studies for potential health hazards from exposure to cell phone radiations. Epigenetic modulations play a critical regulatory role in many cellular functions and pathological conditions. In this study, we assessed the dose-dependent and frequency-dependent epigenetic modulation (DNA and Histone methylation) in the hippocampus of Wistar rats. A Total of 96 male Wistar rats were segregated into 12 groups exposed to 900 MHz, 1800 MHz and 2450 MHz RF-MW at a specific absorption rate (SAR) of 5.84 × 10-4 W/kg, 5.94 × 10-4 W/kg and 6.4 × 10-4 W/kg respectively for 2 h per day for 1-month, 3-month and 6-month periods. At the end of the exposure duration, animals were sacrificed to collect the hippocampus. Global hippocampal DNA methylation and histone methylation were estimated by ELISA. However, DNA methylating enzymes, DNA methyltransferase1 (DNMT1) and histone methylating enzymes euchromatic histone methylthransferase1 (EHMT1) expression was evaluated by real-time PCR, as well as further validated with Western blot. Alteration in epigenetic modulation was observed in the hippocampus. Global DNA methylation was decreased and histone methylation was increased in the hippocampus. We observed that microwave exposure led to significant epigenetic modulations in the hippocampus with increasing frequency and duration of exposure. Microwave exposure with increasing frequency and exposure duration brings significant (p < 0.05) epigenetic modulations which alters gene expression in the hippocampus.
journal_name
Environ Resjournal_title
Environmental researchauthors
Kumar R,Deshmukh PS,Sharma S,Banerjee BDdoi
10.1016/j.envres.2020.110297subject
Has Abstractpub_date
2021-01-01 00:00:00pages
110297eissn
0013-9351issn
1096-0953pii
S0013-9351(20)31194-4journal_volume
192pub_type
杂志文章abstract:BACKGROUND:Information about local air quality is reported across the United States using air quality alerts such as the Environmental Protection Agency's Air Quality Index. However, the role of such alerts in raising awareness of air quality is unknown. We conducted this study to evaluate associations between days wit...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109185
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Chronic exposure to inorganic arsenic (iAs) in the US occurs mainly through drinking water and diet. Although American Indian (AI) populations have elevated urinary arsenic concentrations compared to the general US population, dietary sources of arsenic exposure in AI populations are not well characterized. ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108616
更新日期:2019-10-01 00:00:00
abstract::Some studies have reported an association between overexposure to selenium and risk of amyotrophic lateral sclerosis (ALS), a rare degenerative disease of motor neurons. From 1986 through 2015, we followed a cohort in Northern Italy that had been inadvertently consuming tap water with unusually high concentrations of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108742
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:There is mixed evidence implicating prenatal exposure to particulate matter <2.5 μm in aerodynamic diameter (PM2.5) in the risk of gestational diabetes mellitus (GDM) and only one study has examined exposure to PM2.5 constituents, which vary with location because of different emission sources. METHODS:We co...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109988
更新日期:2020-11-01 00:00:00
abstract::There is only limited monitoring data of black carbon for epidemiologic analyses. In the current study, we used the distributed lag models to evaluate the association between mortality outcomes (both total and cause-specific) and exposure to black carbon and fine particle (PM(2.5)) in Shanghai, China. During our resea...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.08.007
更新日期:2013-01-01 00:00:00
abstract::Due to the increase in the occurrence of bisphenols (BPs) in the environments, it is urgent to develop efficient and ecofriendly methods for their removal. A novel, indirect Z-scheme TiO2-C-BiVO4 film was prepared by a sol-gel method combined with hydrothermal carbonization. The doped graphite carbon was generated in ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110221
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:In previous studies investigating the short-term health effects of ambient air pollution the exposure metric that is often used is the daily average across monitors, thus assuming that all individuals have the same daily exposure. Studies that incorporate space-time exposures of individuals are essential to ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.03.017
更新日期:2017-07-01 00:00:00
abstract::2,4,6-trinitrophenol (TNP) is environmentally deleterious substance that has been of pressing societal concern. Therefore, developing a convenient and reliable platforms for its fast and efficient detection is of paramount importance from security point of view. Herein, amphiphilic fluorescent carbon dots (CDs) were p...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108621
更新日期:2019-10-01 00:00:00
abstract::Baseline blood concentrations of metals are important references for monitoring metal exposure in environmental and occupational settings. The purpose of this study was to determine the blood levels of manganese (Mn), copper (Cu), zinc (Zn), lead (Pb), and cadmium (Cd) among the residents (aged 12-60 years old) living...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.03.008
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Epidemiological evidence regarding the relationship between maternal secondhand smoke (SHS) exposure during pregnancy and postnatal SHS exposure and childhood behavioral problems is scarce. OBJECTIVE:The present prebirth cohort study investigated the association between perinatal smoking exposure and behavi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.08.010
更新日期:2016-11-01 00:00:00
abstract::In 1925, Robert A. Kehoe enunciated a paradigm predicated upon categorical distinction between expectations and conjecture ("show me the data" mentality) from hard scientific facts on exposure outcomes. It led to a precedent-setting system of voluntary self-regulation by lead industry as a model for environmental cont...
journal_title:Environmental research
pub_type: 传,历史文章,杂志文章
doi:10.1006/enrs.1997.3808
更新日期:1998-08-01 00:00:00
abstract::There is mounting evidence that maternal exposure to ambient air pollution during pregnancy is associated with adverse birth outcomes. We examined birth weight and small for gestational age (SGA <10th percentile for age and gender) among 26,617 singleton full-term births in Brisbane, Australia (July 2000-June 2003), i...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2006.06.010
更新日期:2007-03-01 00:00:00
abstract::Large areas of mainland China have been suffering frequently from heavy haze pollution during the past years, which feature high concentrations of fine particulate matter (PM2.5, particulate matters with aerodynamic diameters less than 2.5 μm) and low visibility. Moreover, these areas manifested strong regional comple...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109368
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Carbamate pesticides exposure have been linked with adverse health effects during developmental period. Based on 377 mother-child pairs from Sheyang Mini Birth Cohort Study, the present study aimed to assess carbofuranphenol exposure of three-year-old children and explore the associations between prenatal or...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108590
更新日期:2019-10-01 00:00:00
abstract::The cytotoxic activity of the DQ-12 standard dust on the external structure of peritoneal macrophages, after intraperitoneal introduction, was investigated, vs nontreated macrophages, and kept in in vitro cultures for 3, 6, and 24 hr. The alterations related to the external structure were investigated by scanning elec...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90002-6
更新日期:1983-08-01 00:00:00
abstract::A massive fire at a sulfur stockpile in the Western Cape Province of South Africa in December 1995 is estimated to have released over 14,000 t of sulfur dioxide (SO(2)) over a 20-h period. High and persistent winds greatly reduced the effectiveness of fire-fighting activities and increased the severity of impacts. Nea...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1999.3990
更新日期:1999-11-01 00:00:00
abstract::Few studies investigate the impact of air pollution on the leading cause of infant morbidity, acute bronchiolitis. We investigated the influence of PM(2.5) and other metrics of traffic-derived air pollution exposure using a matched case-control dataset derived from 1997 to 2003 birth and infant hospitalization records...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.11.006
更新日期:2009-04-01 00:00:00
abstract::Climate change is one of the biggest and most urgent challenges for the 21st century. Rising average temperatures and ocean levels, altered precipitation patterns and increased occurrence of extreme weather events affect not only the global landscape and ecosystem, but also human health. Multiple environmental factors...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2019.108637
更新日期:2019-10-01 00:00:00
abstract::Chlorinated solvents (CS)-contaminated groundwater poses serious risks to the environment and public health. Microorganisms play a vital role in efficient remediation of CS. In this study, the microbial community (bacterial and archaeal) composition of three CS-contaminated groundwater wells located at an abandoned ch...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109457
更新日期:2020-06-01 00:00:00
abstract::Soil polycyclic aromatic hydrocarbons (PAHs) contamination caused by factory relocations is a serious environmental issue across the world. Electrical resistance heating (ERH) and chemical oxidation are two promising in-situ methods for treating volatile and semi-volatile organic pollutants in contaminated soil. Coupl...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110457
更新日期:2020-11-11 00:00:00
abstract::The role of humic acids in the transport of trace elements in the Sava river biocycle (near Zagreb, Yugloslavia) has been investigated by means of neutron activation analysis. Humic acids can accumulate certain trace elements, but little is known about their selectivity under certain physicochemical conditions. Humic ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80052-4
更新日期:1986-04-01 00:00:00
abstract::This study employs dynamic panel data for 34 Sub Saharan Africa (SSA) countries for the period 1984-2016 to estimate the effects of renewable energy on environmental quality measured by three indicators, namely, per capita CO2 emissions, energy intensity (EI) and Aggregate National Savings (ANS). The study leveraged a...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110094
更新日期:2020-12-01 00:00:00
abstract::Mercury (Hg) has been shown to have immunotoxic effects and to influence the severity of infection. However, the impact of infection on the normal Hg homeostasis in different target organs involved in the disease process has not been studied. In this study, Hg was measured through inductively coupled plasma-mass spect...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.08.002
更新日期:2008-02-01 00:00:00
abstract::Contamination of water by cyanobacteria (blue-green algae) is a serious health problem around the world, largely due to the toxic effects of microcystins, a group of potent hepatotoxins. However, the mechanisms responsible for the cytotoxicity of microcystins have not been fully elucidated. In the present study, oxida...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1998.3843
更新日期:1998-07-01 00:00:00
abstract::Penicillic acid (PA) is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. This mycotoxin is toxic in experimental animals and has also been reported to be carcinogenic. The cytotoxicity of penicillic acid was studied in rat alveolar macrophages (AM) in vitro. The effects of penicillic ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80145-1
更新日期:1986-12-01 00:00:00
abstract::In 1976, the New York Giants professional football team relocated to the newly constructed Meadowlands Sports Complex (MSC) in East Rutherford, NJ. Between 1980 and 1987 four team members developed cancer: one case each of non-Hodgkin's lymphoma, glioblastoma, angiosarcoma, and Hodgkin's disease. Because the surroundi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(05)80003-9
更新日期:1991-12-01 00:00:00
abstract::Despite the behaviors of ZnO nanoparticles (ZnO NPs) in wastewater treatment processes have been widely explored, the impacts of ZnO NPs on the activated sludge's flocculation and sedimentation performances for solid-liquid separation have rarely been involved yet. In this study, ZnO NPs were observed to exert a dose-...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110256
更新日期:2021-01-01 00:00:00
abstract::Hamsters were exposed to an intratracheal instillation of 0.5 ml of 0.08 N nitric, hydrochloric, or sulfuric acid to determine their airway epithelial response. Three weeks after exposure, the left intrapulmonary bronchi in Alcian blue/PAS-stained paraffin sections were evaluated for the amount of secretory product in...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(88)80010-0
更新日期:1988-02-01 00:00:00
abstract:PURPOSE:Knowledge about changes in exposure to toxic metals over time remains very sparse, in particular for children, the most vulnerable group. Here, we assessed whether a reduction in environmental pollution with cadmium (Cd) and mercury (Hg) caused a change in exposure over time. In total, 1257 children (age 4-9) i...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.02.016
更新日期:2016-10-01 00:00:00
abstract::Urinary β2-microgroblin (β2-MG) excretion levels above 300 μg/g creatinine are used to indicate defective tubular reabsorption. Arguably, increased urinary β2-MG excretion could also reflect glomerular filtration rate decline. Thus, we investigated an association between urinary β2-MG and estimated glomerular filtrati...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.03.026
更新日期:2019-06-01 00:00:00