Abstract：
:In a longitudinal study, we assessed the relation between daily exposure to ambient air malodorous sulfur compounds from pulp production and experience of symptoms in a small population living in the vicinity of a pulp mill. Special emphasis was laid on exposure-response pattern, where the intensity of the symptoms of interest was assessed in six consecutive questionnaires after three predefined levels of exposure to malodorous sulfur compounds [total reduced sulfur (TRS)] (reference: daily mean < 10 micrograms/m3, medium exposure: 10-30 micrograms/m3 high exposure: > 30 micrograms/m3). The study population included 81 adults, who responded to the baseline questionnaire (response rate 81%). The outcomes of interest were eye, respiratory, and central nervous symptoms. The mean daily intensity of the outcome symptoms, but not of control symptoms, was significantly higher on days of medium and high exposure compared with the reference days (paired t test). The probability ratios between experiencing more or fever symptoms during the medium and high exposure compared with reference days were increased for all the symptoms of interest with a consistent exposure response pattern. The probability ratios were for eye symptoms 3.17, 95% confidence intervals (CI) 1.21 to 7.47 (medium exposure), and 5.0, 95% CI 1.66 to 12.65 (high exposure); for nasal symptoms 3.13, 1.25 to 7.25 (medium), and 8.50, 3.19 to 18.64 (high); and for pharyngeal symptoms 2.0, 0.92 to 4.14 (medium) and 5.20, 1.95 to 11.99 (high). The results suggest that relatively low daily levels of malodorous sulfur compounds (TRS > 10 micrograms/m3) cause exposure-related short-term adverse effects.
journal_name
Environ Resjournal_title
Environmental researchauthors
Marttila O,Jaakkola JJ,Partti-Pellinen K,Vilkka V,Haahtela Tdoi
10.1006/enrs.1995.1073subject
Has Abstractpub_date
1995-11-01 00:00:00pages
122-7issue
2eissn
0013-9351issn
1096-0953pii
S0013935185710730journal_volume
71pub_type
杂志文章abstract：:A major challenge in both the design of epidemiologic studies of exposure to toxic agents and the interpretation of the findings is to recognize and to accommodate the complex biologic assumptions that underlie population-based research. Environmental health research is grounded on a scientific foundation that blends ...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/s0013-9351(05)80229-4
更新日期：1992-10-01 00:00:00
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doi：10.1016/j.envres.2019.108715
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.02.030
更新日期：2015-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90163-9
更新日期：1983-02-01 00:00:00
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journal_title：Environmental research
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doi：10.1016/j.envres.2017.11.028
更新日期：2018-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110146
更新日期：2020-12-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.03.056
更新日期：2017-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(85)90076-3
更新日期：1985-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3718
更新日期：1997-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.09.014
更新日期：2014-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80088-9
更新日期：1987-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80003-9
更新日期：1991-12-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2013.08.012
更新日期：2013-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.11.042
更新日期：2018-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.05.012
更新日期：2017-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3752
更新日期：1997-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2003.08.008
更新日期：2004-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.04.009
更新日期：2007-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2009.07.005
更新日期：2009-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-10-01 00:00:00
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更新日期：2021-01-20 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.envres.2016.05.002
更新日期：2016-08-01 00:00:00
abstract：:Fifty-two pesticide sprayers in cotton fields were selected for the analysis of chromosomal aberrations in peripheral lymphocytes. Twenty-five samples were collected from healthy males who were not exposed to pesticides. Statistical analysis revealed that there was a significant increase in chromosomal aberrations in ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(89)80017-9
更新日期：1989-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90019-1
更新日期：1983-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.04.020
更新日期：2015-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2016.01.018
更新日期：2016-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90002-6
更新日期：1983-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.09.009
更新日期：2018-01-01 00:00:00
abstract：:Cytogenetic investigations were carried out on 50 workers exposed to stone dust in a stone crusher industry and on 25 control subjects never exposed to such dust. The frequency of chromosomal aberrations and sister chromatid exchanges in exposed individuals was significantly higher than that in controls (P less than 0...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80106-9
更新日期：1991-10-01 00:00:00
