Abstract:
:Human nail clippings have been used in recent epidemiological studies as a routine bioindicator of arsenic and selenium exposure. To ensure sound application of this biomarker, however, it is important to consider properties and scientific knowledge pertaining to validation of this particular tool. In this review, the use of human nails to measure exposure to arsenic and selenium is discussed in the context of the biomarker validation framework. Literature related to both analytical procedures and intrinsic characteristics of the biomarker is reviewed. Specifically, the followings are addressed: sample collection and preparation methods, establishment of the exposure-biomarker relationship, intraindividual variability and reproducibility of measurements, and biomarker-disease investigations. Drawing from a rapidly growing body of literature, current knowledge of these biomarker validation steps is assessed. Therefore, this review brings attention to the important issue of biomarker validation, laying the framework for future studies measuring elemental composition of nails.
journal_name
Environ Resjournal_title
Environmental researchauthors
Slotnick MJ,Nriagu JOdoi
10.1016/j.envres.2005.12.001subject
Has Abstractpub_date
2006-09-01 00:00:00pages
125-39issue
1eissn
0013-9351issn
1096-0953pii
S0013-9351(05)00190-8journal_volume
102pub_type
杂志文章,评审abstract::Fish are a healthy source of protein and nutrients, but contaminants in fish may provide health risks. Determining the risk from contaminants in fish requires site-specific information on consumption patterns. We examine consumption rates for resident and expatriates in the Jeddah region of Saudi Arabia, by species of...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.05.014
更新日期:2014-08-01 00:00:00
abstract::Comparative growth rates were monitored in the Pacific oyster, Crassostrea gigas, at two sites in Singapore, one uncontaminated and the other contaminated with respect to ambient seawater quality. Growth rates differed significantly at the two sites, revealing that marine water quality can have potentially adverse eff...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2006.06.012
更新日期:2007-03-01 00:00:00
abstract::Epidemiological studies often focus on risk assessments associated with exposures to specific air pollutants or proximity to different air pollution sources. Although this information is essential for devising informed health policies, it is not always helpful when it comes to the estimation of potential health effect...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.109088
更新日期:2020-03-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4240
更新日期:2001-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1006/enrs.1993.1131
更新日期:1993-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envres.2018.02.030
更新日期:2018-07-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.12.006
更新日期:2016-04-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.04.015
更新日期:2019-07-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.05.009
更新日期:2008-03-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,meta分析
doi:10.1016/j.envres.2019.108884
更新日期:2020-01-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.11.020
更新日期:2016-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90004-x
更新日期:1983-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110336
更新日期:2020-10-20 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/s0013-9351(02)00009-9
更新日期:2003-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110565
更新日期:2021-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.03.036
更新日期:2014-07-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.09.002
更新日期:2016-11-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.06.005
更新日期:2018-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(85)90061-1
更新日期:1985-06-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(84)90146-4
更新日期:1984-12-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envres.2005.06.007
更新日期:2006-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.12.031
更新日期:2019-03-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2013.07.007
更新日期:2013-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2009.01.005
更新日期:2009-07-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2004.05.013
更新日期:2005-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2010.05.009
更新日期:2010-08-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.07.020
更新日期:2008-11-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.03.040
更新日期:2019-06-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109368
更新日期:2020-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109192
更新日期:2020-04-01 00:00:00