Trends and variations in intravenous vitamin D use among hemodialysis patients in the United States.

Abstract:

:Injectable vitamin D agents are commonly used to manage secondary hyperparathyroidism in dialysis patients. Yet, there are few data documenting the trends and geographic variations in the use of these agents in large, representative samples. We sought to describe patterns and variations in the use of vitamin D formulations (calcitriol, paricalcitol, and doxercalciferol) in hemodialysis patients. We studied patients in the United States Renal Data System between January1999 and December 2008 with Medicare as a primary payer. Annual percentages of patients treated with each type of formulation were tabulated by race, sex, and age at dialysis initiation. The geographical distribution of vitamin D dose per patient was mapped at the state level. Intravenous vitamin D use has increased sharply from 1999 to 2008 with 83.9% of patients treated with any vitamin D formulation in 2008. The use of calcitriol has declined since 1999, going from being administered in 58.6% of patients in 1999 to 1.8% in 2008. Paricalcitol was found to be the overwhelmingly preferred formulation during the study years. In 2008, the average dose among black patients was 84% greater than among white patients (136 mcg vs. 73.6 mcg). Higher doses of vitamin D were administered to patients in the southern region of the country. Vitamin D use has increased and parallels the rise in use of paricalcitol and doxercalciferol. Given the variations in use and known pharmacologic differences in vitamin D formulations, future research should focus on whether the formulations differentially affect patient outcomes.

journal_name

Ren Fail

journal_title

Renal failure

authors

Beaubrun AC,Brookhart MA,Sleath B,Wang L,Kshirsagar AV

doi

10.3109/0886022X.2012.734260

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

1-8

issue

1

eissn

0886-022X

issn

1525-6049

journal_volume

35

pub_type

杂志文章
  • SDS-electrophoresis of unconcentrated urine samples using a semi-automatic method.

    abstract::The study of urinary proteins is an important tool in the screening and diagnosis of patients with renal impairment. Quantification of total proteins, although useful, can provide only limited information. Gel electrophoresis of urine samples may provide more detailed information. ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229909085105

    authors: Behets GJ,De Broe ME

    更新日期:1999-05-01 00:00:00

  • Nephro-oncology: a link in evolution.

    abstract::A multidisciplinary approach represents the best method to interact with patients. Neoplastic and renal diseases are closely related to each other because of an increased risk of cancer among individuals with end-stage renal disease and because of the high prevalence of renal failure in cancer patients. Physicians sho...

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.3109/0886022X.2015.1068514

    authors: Lacava V,Coppolino G,Puntorieri E,Cernaro V,Lupica R,Visconti L,Buemi A,Santoro D,Buemi M

    更新日期:2015-01-01 00:00:00

  • Bcıı--RFLP profiles for serum amiloid A1 and mutated MEFV gene prevalence in chronic renal failure patients requiring long-term hemodialysis.

    abstract:BACKGROUND AND AIM:There is an increased mortality risk in long-term hemodialysis patients of renal failure due to the chronic inflammation. The relationship between the chronic renal failure (CRF) and the role of familial genetic markers remains incompletely understood. In the current study, it was aimed to find out t...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.982954

    authors: Ozdemir O,Kayatas M,Cetinkaya S,Yildirim ME,Silan F,Kurtulgan HK,Koksal B,Urfali M,Candan F

    更新日期:2015-03-01 00:00:00

  • A reference equation for objectively adjusting dwell volume to obtain more ultrafiltration in daily practice of peritoneal dialysis.

    abstract:OBJECTIVES:Few studies mention how to objectively adjust peritoneal dialysis (PD) dwell volume for adult continuous ambulatory peritoneal dialysis (CAPD) patients. We proposed a reference equation composed of parameters from the peritoneal equilibrium test (PET) for adjusting daily dialysate dwell volume to obtain more...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860220903541127

    authors: Chien CC,Wang HY,Chien TW,Kan WC,Su SB,Lin CY

    更新日期:2010-01-01 00:00:00

  • The role of mitofilin in left ventricular hypertrophy in hemodialysis patients.

    abstract::Left ventricular hypertrophy (LVH) is a common abnormality in hemodialysis (HD) patients. Mitochondrial dysfunction contributes to the progression of LVH. As an inner mitochondrial membrane structural protein, mitofilin plays a key role in maintaining mitochondrial structure and function. The aim of this study was to ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2018.1456455

    authors: Wu QS,He Q,He JQ,Chao J,Wang WY,Zhou Y,Lou JZ,Kong W,Chen JF

    更新日期:2018-11-01 00:00:00

  • Development of new nephrons in adult kidneys following gentamicin-induced nephrotoxicity.

    abstract::Gentamicin-induced nephrotoxicity results in necrosis of proximal tubular epithelial cells. In mammals, the injured nephron can be repaired by migration and division of surviving cells. We examined this repair process in the fresh-water goldfish, Carassius auratus. Fish were given a single intraperitoneal injection of...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229509026246

    authors: Reimschuessel R,Williams D

    更新日期:1995-03-01 00:00:00

  • Hypocomplementemia is associated with more severe renal disease and worse renal outcomes in patients with ANCA-associated vasculitis: a retrospective cohort study.

    abstract:BACKGROUND:The complement system has been recently proposed to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). This study evaluated the value of serum and kidney deposited C3 in predicting renal outcomes in AAV. METHODS:This was a retrospective study of 47 patients with AAV, who were ca...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1803086

    authors: Chalkia A,Thomas K,Giannou P,Panagiotopoulos A,Hadziyannis E,Kapota A,Gakiopoulou H,Vassilopoulos D,Petras D

    更新日期:2020-11-01 00:00:00

  • Osmotic diuretics and hemodilution in postischemic renal failure.

    abstract::In the acute phase of ischemic renal failure, the severe depression of the glomerular filtration rate (GFR) is due to obstruction of the tubules by cells and cell debris rejected from the proximal tubules, a blockade which can be prevented at least partly, by treatment with osmotic diuretics. The isosthenuria, the sec...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229209106632

    authors: Wolgast M,Bayati A,Hellberg O,Källskog O,Nygren K

    更新日期:1992-01-01 00:00:00

  • Assessment of protein nitrogen appearance in Chinese peritoneal dialysis patients-which method to use?

    abstract:OBJECTIVE:We compared the Bergstrom's and Randerson's formula for PNA determination, and compared the normalization of PNA by ideal body weight (IBW) and standard body weight (SBW) as estimated by the Watson's formula. METHODS. We studied 208 Chinese PD patients. Two 24-h dialysate and urine collections were performed ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120018724

    authors: Szeto CC,Chow KM,Leung CB,Wong TY,Li PK

    更新日期:2003-03-01 00:00:00

  • Urotensin-II immunoreactivity in children with chronic glomerulonephritis.

    abstract:BACKGROUND:Human urotensin-II (hU-II) is one of the most potent vasoconstrictors in mammals. To our knowledge, there is no study about the role of U-II in childhood glomerulonephritis. We first determined the expression of h U-II in kidneys of children with chronic glomerular diseases. METHODS:Normal human kidneys wer...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701392108

    authors: Balat A,Karakök M,Yilmaz K,Kibar Y

    更新日期:2007-01-01 00:00:00

  • Current evidence on the use of anti-RAAS agents in congenital or acquired solitary kidney.

    abstract:RATIONAL:The inhibition of renin-angiotensin-aldosterone system (RAAS) is a major strategy for slowing the progression of chronic kidney disease (CKD). The utility of anti-RAAS agents in patients with congenital or acquired solitary kidney is still controversial. OBJECTIVE:A systematic literature review was conducted....

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.1080/0886022X.2017.1361840

    authors: Simeoni M,Armeni A,Summaria C,Cerantonio A,Fuiano G

    更新日期:2017-11-01 00:00:00

  • Effects of dietary protein on renal ischemia induced tubular necrosis.

    abstract::Previously we have shown that the amount of protein in a dietary regimen prior to the induction of renal ischemia will significantly affect the degree of postischemic acute renal failure (Andrews PM, Bates SB: Kidney Int 30:299-303, 1986). The present investigation was undertaken to determine what effect dietary prote...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229309065566

    authors: Andrews PM

    更新日期:1993-01-01 00:00:00

  • Chronic renal disease in Kuwaiti nationals: a prospective study during the past 4 years.

    abstract::Our study is a prospective one conducted at Al-Amiri Hospital and including all new cases of chronic renal disease (CRD) seen at the capital area of Kuwait between 1 January 1999 and 30 December 2003. Diagnosis of CRD was based on clinical, laboratory, and radiological features. Kidney biopsies were done when indicate...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: El-Reshaid W,El-Reshaid K,Kapoor M,Hakim A

    更新日期:2005-01-01 00:00:00

  • Ureteral anastomosis with a polyimide stent in rat kidney transplantation.

    abstract::Background: Complications associated with ureteral anastomosis in kidney transplantation are highly prevalent, despite the development of various types of stents. The current stent materials and placement methods have several limitations. This study attempts to provide an alternative by investigating ureteral anastomo...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1726386

    authors: Wang T,Yu Z,Chen C,Song Y,Zeng X,Su Y,Yi C

    更新日期:2020-11-01 00:00:00

  • The effects of spironolactone on nephron function in patients with diabetic nephropathy.

    abstract::Increasing evidence suggests that circulating aldosterone per se contributes directly to renal and cardiovascular diseases. We sought to evaluate the effects of a three-month treatment with 25 mg spironolactone, an aldosterone receptor antagonist, on nephron function in 20 type II diabetic patients with persistent mic...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.1080/08860220802389342

    authors: Ustundag A,Tugrul A,Ustundag S,Sut N,Demirkan B

    更新日期:2008-01-01 00:00:00

  • What has changed in the prevalence of hypertension in dialyzed children during the last decade?

    abstract:BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

    journal_title:Renal failure

    pub_type: 杂志文章,多中心研究

    doi:10.1080/0886022X.2016.1260033

    authors: Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

    更新日期:2017-11-01 00:00:00

  • Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells.

    abstract:BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2017.1419972

    authors: Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

    更新日期:2018-11-01 00:00:00

  • Protective effect of N-benzoyl-beta-alanine against cisplatin nephrotoxicity in rats.

    abstract::Prophylactic effects of N-benzoyl-beta-alanine (betamipron, BP), one of a series of N-acyl amino acids, were examined against cisplatin-induced nephrotoxicity. Male Wistar rats were injected i.p. with 6 mg/kg of cisplatin combined with an i.p. BP dose given at various times and various doses. Rats were sacrificed 5 da...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229609052792

    authors: Tokunaga J,Kobayashi M,Nakamura C,Kitagawa A,Arimori K,Nakano M

    更新日期:1996-03-01 00:00:00

  • Effect of fenoldopam on ischemia/reperfusion-induced apoptosis.

    abstract::Recently we demonstrated the effect of fenoldopam on ischemia/reperfusion (I/R) induced NFkappaB mediated pro-inflammatory signal transduction. However, the effect of fenoldopam on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothesis that fenoldopam attenuate...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220600583690

    authors: Aravindan N,Cata JP,Dougherty PM,Shaw AD

    更新日期:2006-01-01 00:00:00

  • Urinary transforming growth factor-beta1 excretion in renal allograft recipients during the early post-transplantation period.

    abstract:BACKGROUND:Transforming growth factor-beta1 (TGF-beta1), the major fibrogenic growth factor, is implicated in the pathogenesis of renal scarring in experimental and clinical nephropathies as well as in chronic allograft nephropathy. In this study we examined the pattern of changes of TGF-beta1 excretion in the urine an...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120022547

    authors: Goumenos DS,Tsakas S,Karavias D,Savidaki I,Karatzas T,Vlachojannis JG

    更新日期:2003-07-01 00:00:00

  • Atrial natriuretic peptide as a preload depressor in acute renal failure secondary to congestive heart failure.

    abstract::The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.3109/08860229809045168

    authors: Seta K,Hayashi T,Sugawara A,Kasuno K,Watanabe S,Sumi Y,Kijima Y,Kawaguchi K,Kotake C,Seo T,Toda T,Kuwahara T

    更新日期:1998-09-01 00:00:00

  • Safety and efficacy of fluvastatin in hyperlipidemic patients with chronic renal disease.

    abstract:BACKGROUND:There are few reports on the safety and efficacy of long-term treatment with statins in patients with chronic renal disease and hyperlipidemia. We evaluated these subjects treated with fluvastatin. METHODS:After a 4-week run-in period, a total of 80 patients with diabetic nephropathy or chronic glomerulonep...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1081/jdi-120039826

    authors: Yasuda G,Kuji T,Hasegawa K,Ogawa N,Shimura G,Ando D,Umemura S

    更新日期:2004-07-01 00:00:00

  • Effect of hormone replacement therapy on CD4+ and CD8+ numbers, CD4+/CD8+ ratio, and immunoglobulin levels in hemodialysis patients.

    abstract::Uremia induces a suppression of the immune status. A large clinical literature suggests that estradiol (E2) plays a critical role in immune function. A large proportion of women hemodialysis patients faced early menopause and inadequate estrogen levels. The aim of the present study is to evaluate the effect of hormone...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Dogan E,Erkoc R,Demir C,Sayarlioglu H,Dilek I,Sayarlioglu M

    更新日期:2005-01-01 00:00:00

  • Tocilizumab treatment for nephrotic syndrome due to amyloidosis in Behcet's disease.

    abstract::Renal involvement is an unusual but significant Behcet´s disease (BD) complication and AA amyloidosis appears to be the most common etiology. IL-6 is a pro-inflammatory cytokine with an important role in AA amyloidosis development. Tocilizumab (TCZ) is a humanized anti-IL-6 receptor antibody that has emerged as an eff...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.773913

    authors: Redondo-Pachón MD,Enríquez R,Sirvent AE,Andrada E,Noguera-Pons R,Millán I,Amorós F

    更新日期:2013-01-01 00:00:00

  • Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats.

    abstract::This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2016.1254659

    authors: Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

    更新日期:2017-11-01 00:00:00

  • Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.832308

    authors: Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

    更新日期:2014-02-01 00:00:00

  • Event- and time-based prospective memory in hemodialysis patients.

    abstract:OBJECTIVE:The present study investigated whether hemodialysis (HD) patients exhibit future memory impairment (PM; the capability of remembering to perform expected future actions) and exploring relevant factors of PM task performance. METHODS:Sixty HD patients and 60 healthy controls matched by age are enrolled in the...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1835673

    authors: Wang B,Li M,Tang F,Wang Y,Han Y,Lu W,Zhang L,Zhang L,Ni W,Zhang L,Zhang L

    更新日期:2020-11-01 00:00:00

  • Protective effect of curcumin on busulfan-induced renal toxicity in male rats.

    abstract:AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1818580

    authors: Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

    更新日期:2020-11-01 00:00:00

  • Intensification of peritoneal dialysis improves valacyclovir neurotoxicity.

    abstract::Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal,...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.743914

    authors: Pipili C,Pantelias K,Deda E,Tsiamalos P,Kostis E,Grapsa E

    更新日期:2013-01-01 00:00:00

  • Fasudil ameliorates rhabdomyolysis-induced acute kidney injury via inhibition of apoptosis.

    abstract::During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI) can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI. We investigated the therapeutic effect of an early application of fasudil on AKI induced by rhabdomyolysis and explored the potential mecha...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.601830

    authors: Wang YD,Zhang L,Cai GY,Zhang XG,Lv Y,Hong Q,Shi SZ,Yin Z,Liu XF,Chen XM

    更新日期:2011-01-01 00:00:00