Abstract:
OBJECTIVE:We compared the Bergstrom's and Randerson's formula for PNA determination, and compared the normalization of PNA by ideal body weight (IBW) and standard body weight (SBW) as estimated by the Watson's formula. METHODS. We studied 208 Chinese PD patients. Two 24-h dialysate and urine collections were performed six months apart. Protein nitrogen appearance was determined by the Randerson's formula (PNA-Rand) and Bergstrom's formula (PNA-Berg), the latter used as the gold standard. PNA-Berg was normalized with IBW and SBW, denoted as NPNA-IBW and NPNA-Watson respectively. The change of PNA over six months, denoted as APNA-Rand and APNA-Berg, were calculated. The results were compared by the Bland and Altman's method. RESULTS:At zero month, the average PNA-Berg was 61.8 +/- 14.8 g/day, and the average PNA-Rand was 58.1 +/- 14.5 g/day. The value of PNA-Rand was consistently lower than the corresponding PNA-Berg. The bias of PNA-Rand was -3.7g/day. The limits of agreement were -9.2 to +1.8 g/day. When NPNA-Watson was compared to NPNA-IBW, the bias of NPNA-Watson, using NPNA-IBW as gold standard, was 0.01 g/kg/day; the limits of agreement were -0.22 to +0.23 g/kg/day. The difference between NPNA-Watson and NPNA-IBW correlated with the body mass index (r = -0.820, p < 0.001) and body weight (r = -0.834, r < 0.001). After six month, there was a significant reduction in urine protein loss. However, total protein loss was only slightly reduced (7.3 +/- 3.0 to 6.9 +/- 2.8 g/day, p = 0.029). The correlation between APNA-Berg and APNA-Rand remained excellent (r = 0.983, p < 0.001). The bias of APNA-Rand was +0.3 g/day; the limits of agreement were -4.7 to +5.2 g/day. CONCLUSION:Ideal body weight that is validated for specific ethnic group, rather than the Watson's formula, should be used for normalization of PNA. Although the Randerson's formula under-estimates PNA when compared to the Bergstrom's formula, it is a reliable method for serial PNA monitoring because dialysate protein loss is stable in most patients.
journal_name
Ren Failjournal_title
Renal failureauthors
Szeto CC,Chow KM,Leung CB,Wong TY,Li PKdoi
10.1081/jdi-120018724subject
Has Abstractpub_date
2003-03-01 00:00:00pages
235-46issue
2eissn
0886-022Xissn
1525-6049journal_volume
25pub_type
杂志文章相关文献
RENAL FAILURE文献大全abstract:BACKGROUND:Advanced glycation end products (AGEs) have biological properties that may contribute to the mortality of children on hemodialysis (HD). This study examines the relationship of LMW fluorescence AGEs, oxidized LDL (ox-LDL), soluble receptor AGE (sRAGE) as markers of oxidative stress in children with end stage...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1077317
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...
journal_title:Renal failure
pub_type: 杂志文章,随机对照试验
doi:10.3109/0886022X.2016.1172917
更新日期:2016-11-01 00:00:00
abstract::The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...
journal_title:Renal failure
pub_type: 临床试验,杂志文章
doi:10.3109/08860229809045168
更新日期:1998-09-01 00:00:00
abstract::Investigations were done in 10- and 55-day-old Wistar rats. Glutathione (GSH) level in kidney was decreased by 8 mmol buthionine sulfoximine (BSO)/100 g BW. There was no effect on the renal function and nephrotoxicity of cisplatin (0.6 mg CP/100 g BW) in adult rats. In young rats BSO treatment was followed by nephroto...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229309046144
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To describe the epidemiologic features of acute renal failure related to pregnancy (PRARF) and to evaluate its prognostic impact. METHODS:Retrospective study conducted in a Tunisian intensive care unit over a period of 17 years (1995-2011). Women were included if they were more than 20 weeks pregnant and were ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.819767
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The goal of this study was to define the clinical and histological differences in new-onset IgA nephropathy between young adults and the elderly. METHODS:We retrospectively examined renal biopsy findings, clinical features at presentation and outcomes in 82 young adults (mean age 30.3+/-10.2 years) and 17 e...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860221003611687
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Renal cystic disorders (RCD) constitute an important and leading cause of end-stage renal disease (ESRD) in children. It can be acquired or inherited; isolated or associated with extrarenal manifestations. The precise diagnosis represents a difficult clinical challenge. METHODS:The aim of this study was to ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2014.883996
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people. METHODS:In all, 24,886 residents (≥65 years old) were selected f...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2016.1229987
更新日期:2016-11-01 00:00:00
abstract::Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100873
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:This aim of this multi-centric cross-sectional study was to assess the nutritional status in Indian chronic kidney disease (CKD) patients and to compare the nutritional indicators between stage 5 dialyzed (CKD-D) patients below the poverty line (BPL), and stage 3-4 non-dialyzed (CKD-ND) patients above (APL) ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.872570
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:The present study investigated whether hemodialysis (HD) patients exhibit future memory impairment (PM; the capability of remembering to perform expected future actions) and exploring relevant factors of PM task performance. METHODS:Sixty HD patients and 60 healthy controls matched by age are enrolled in the...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2020.1835673
更新日期:2020-11-01 00:00:00
abstract::Oxidative stress is one of the important mechanisms of cisplatin-induced nephrotoxicity. Therefore, this study was designed to explore the potential protective effects of morin and/or hesperidin on oxidative stress in cisplatin-induced nephrotoxicity. This study was performed on 42 Wistar rats. Rats were divided into ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2016.1209383
更新日期:2016-09-01 00:00:00
abstract:RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1062340
更新日期:2015-08-01 00:00:00
abstract::Several studies have shown that hepatocyte growth factor (HGF) ameliorates chronic renal failure, but its mechanism of action is unclear. This study was designed to test the delivery of HGF in the PCI-neo vector, using the 5/6 nephrectomized rat as a model for chronic renal failure, and to confirm that this protective...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2013.867797
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Gastrointestinal complications are frequent in patients with renal disease and are responsible for substantial morbidity and mortality among these patients in developing countries. Many times, these patients are subjected to endoscopic evaluation and mucosal biopsies are taken for definitive diagnosis. This ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.731998
更新日期:2013-01-01 00:00:00
abstract::This study was designed to evaluate the preventive role of melatonin (Mel) and 1,25-dihydroxyvitamin D3 (VD3) in biochemical and apoptotic events leading to tissue injury and renal dysfunction after ischemia-reperfusion (I/R). Thirty male Wistar rats were divided into five groups: sham-operated, I/R, Mel + I/R, VD3 + ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.700887
更新日期:2012-01-01 00:00:00
abstract::During exercise, the plasma urate levels and urinary excretion increase due to the enhanced purine degradation in skeletal muscle. Although urate transporter-1 (URAT1) is the main transporter responsible for the reabsorption of filtered urate, potential changes in its activity and expression during exercise have not b...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2010.494805
更新日期:2010-01-01 00:00:00
abstract::Acute renal failure (ARF) occurs in wide range of conditions, making the evaluation of its prognosis a difficult task. Data regarding prognostic factors in ARF in a general population in developing countries are scarce. The objective of the study was to describe predictors of mortality in ARF that are relevant in the ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220701260651
更新日期:2007-01-01 00:00:00
abstract::This study was designed to investigate whether the treatment with the N-acetyl-L-cysteine prior to the administration of chemotherapy drug would prevent from nephrotoxicity and the loss of reproductive performance induced from chemotherapy treatment. Female rats were divided into five equal groups of six each: 1/contr...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2015.1127742
更新日期:2016-01-01 00:00:00
abstract::Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized meas...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909085095
更新日期:1999-05-01 00:00:00
abstract::Compared to prior studies which frequently pinpoint the impairment of one parameter or function, this paper reports for the first time an extensive characterization of the toxic effects of gentamicin in a single model of primary cultured rabbit proximal tubule cells developed without insulin and glucose. Biochemical, ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229309054962
更新日期:1993-01-01 00:00:00
abstract::The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Normal saline was intraperitoneally and intra...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2018.1561375
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...
journal_title:Renal failure
pub_type: 杂志文章,多中心研究
doi:10.1080/0886022X.2016.1260033
更新日期:2017-11-01 00:00:00
abstract::We present a patient with AL amyloidosis who had an autologous stem cell transplant (ASCT) over 9 years ago. She has since then developed slowly progressive renal insufficiency and the nephrotic syndrome. Hematologic evaluation has failed to identify recurrent disease and a renal biopsy demonstrated extensive amyloid ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2012.669320
更新日期:2012-01-01 00:00:00
abstract::Toxoplasma gondii is one of the important opportunistic pathogen among solid-organ transplant recipients and hemodialysis patients (HD). This study was aimed to detect toxoplasmosis among 50 renal transplant recipients (RTR), 135 HD and 120 healthy individuals in two cities (Kashan and Qom) that located in the center ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2016.1172940
更新日期:2016-07-01 00:00:00
abstract::Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/0886022X.2010.501931
更新日期:2010-01-01 00:00:00
abstract::Although complete blood count is routinely ordered in most upper urinary tract infections (UTI), and information regarding the patient's platelet indices is made available without added cost, the relationship between platelet count and mean platelet volume (MPV) and specific platelet responses to different infectious ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220801947389
更新日期:2008-01-01 00:00:00
abstract::Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/08860220500244781
更新日期:2005-01-01 00:00:00
abstract::Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860220903134571
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:We investigate the mechanism of neutrophil/lymphocyte ratio (NLR) elevation, a useful prognostic marker in patients with cardiovascular diseases (CVDs). METHODS:In this clinical study, we retrospectively searched for factors associated with NLR elevation in cardiovascular outpatients. In animal experiments u...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1080/0886022X.2019.1597736
更新日期:2019-11-01 00:00:00