Lithium dilution, pulse power analysis, and continuous thermodilution cardiac output measurements compared with bolus thermodilution in anaesthetized ponies.

Abstract:

BACKGROUND:This study compares cardiac output (CO) measurements obtained by lithium dilution (LiDCO), pulse power analysis (PulseCO), and continuous thermodilution (CTD) with bolus thermodilution (BTD) in ponies. METHODS:Eight isoflurane-anaesthetized Shetland ponies received xylazine, ketamine, and midazolam infusions (0.3, 1.2, and 0.018 mg kg(-1) h(-1), respectively). CO was measured with BTD, CTD, LiDCO, and PulseCO. Lithium was injected into the jugular vein and blood was sampled from the facial artery for lithium detection and this artery was also used for PulseCO. Measurements were obtained during four stable haemodynamic conditions in the following order: isoflurane 1% (end-tidal concentration), isoflurane 2%, isoflurane 1%, and isoflurane 1%+dobutamine 5 µg kg(-1) min(-1). RESULTS:The bias (2 sd) was 2.5 (2.1) and 0.5 (2.9) litre min(-1) for LiDCO-BTD and for CTD-BTD comparisons, respectively. The limits of agreement were wider than ±30%; therefore, interchangeability was rejected for both comparisons. A possible error in LiDCO might explain the bias observed because CTD-BTD comparison showed less bias. Changes in PulseCO did not correlate with those of BTD and a weak correlation (r(2)=0.23; P=0.018) and concordance (Pc=0.42) was found between CTD and BTD. CONCLUSIONS:This is the first study to show a large bias for LiDCO-BTD comparison in animals receiving xylazine, ketamine, and midazolam infusions. The trending abilities of neither PulseCO nor CTD were reliable. Further studies are needed to elucidate possible influences of drugs on the accuracy of the LiDCOplus system.

journal_name

Br J Anaesth

authors

Ambrisko TD,Coppens P,Kabes R,Moens Y

doi

10.1093/bja/aes269

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

864-9

issue

6

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)31591-X

journal_volume

109

pub_type

杂志文章
  • Early cryoprecipitate for major haemorrhage in trauma: a randomised controlled feasibility trial.

    abstract:BACKGROUND:Low fibrinogen (Fg) concentrations in trauma haemorrhage are associated with poorer outcomes. Cryoprecipitate is the standard source for Fg administration in the UK and USA and is often given in the later stages of transfusion therapy. It is not known whether early cryoprecipitate therapy improves clinical o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aev134

    authors: Curry N,Rourke C,Davenport R,Beer S,Pankhurst L,Deary A,Thomas H,Llewelyn C,Green L,Doughty H,Nordmann G,Brohi K,Stanworth S

    更新日期:2015-07-01 00:00:00

  • Sinus bradycardia associated with traumatic haemothorax.

    abstract::A 39-year-old male suffered a closed chest deceleration injury. He presented with clinical and radiological signs consistent with trauma to the thoracic aorta, but also developed sinus bradycardia which was relieved by drainage of a haemothorax. The possible mechanisms of the changes in heart rate are discussed and di...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/72.3.358

    authors: Kong RS,Wood PR

    更新日期:1994-03-01 00:00:00

  • A comparison of the respiratory effects of meptazinol, pentazocine and morphine.

    abstract::The respiratory effects of a new strong analgesic, meptazinol, were compared with a placebo and with equianalgesic doses of morphine and pentazocine in a double-blind crossover trial in seven healthy volunteers. No significant change in the ventilatory response to rebreathing carbon dioxide was observed after meptazin...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/51.6.497

    authors: Jordan C,Lehane JR,Robson PJ,Jones JG

    更新日期:1979-06-01 00:00:00

  • Effect of different kinds of premedication on the induction properties of midazolam.

    abstract::The effects of different premedication (i.m. and i.v.) on the usefulness of midazolam or thiopentone as induction agents for minor surgery was studied in 194 women undergoing either dilatation and curettage or explorative fractionate curettage. Midazolam appeared to produce light sedation which required powerful preme...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/54.5.507

    authors: Kanto J,Sjövall S,Vuori A

    更新日期:1982-05-01 00:00:00

  • Effect of atropine on the QT interval and T-wave amplitude in healthy volunteers.

    abstract::Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respira...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/71.5.736

    authors: Annila P,Yli-Hankala A,Lindgren L

    更新日期:1993-11-01 00:00:00

  • Anaesthesia for laparoscopic cholecystectomy in a patient with Eisenmenger's syndrome.

    abstract::We describe the management of a patient with Eisenmenger's syndrome presenting for laparoscopic cholecystectomy. Of prime concern was maintenance of systemic vascular resistance and this was achieved using infusion of noradrenaline started before induction of anaesthesia and continued after operation. Avoidance of oth...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/79.6.810

    authors: Sammut MS,Paes ML

    更新日期:1997-12-01 00:00:00

  • Analgesic effect of aprotinin in the rat and its inhibition by naloxone.

    abstract::Experiments were performed on rats using two analgesimetric tests (tail-flick; hot-plate) before and after injection i.v. of graded doses of aprotinin (12.5, 25.0 and 50 KIU g-1). A dose-related analgesic effect was noted with both tests. Prior administration of naloxone 0.001 mg g-1 i.p. inhibited the analgesic actio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/52.11.1107

    authors: Novelli GP,Pieraccioli E,Peduto VA,Festimanni F

    更新日期:1980-11-01 00:00:00

  • Anaesthetic management of renin secreting nephroblastoma.

    abstract::We report the successful preoperative control and anaesthetic management of severe hypertension in a 7-month-old baby with nephroblastoma and increased renin activity. The strategy for selection of appropriate antihypertensive pharmacological agents and the anaesthetic implications and management of the condition are ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/69.2.206

    authors: Charlton GA,Sedgwick J,Sutton DN

    更新日期:1992-08-01 00:00:00

  • Cardiovascular and electroencephalographic effects of laudanosine in "nephrectomized" cats.

    abstract::We studied a cat model simulating laudanosine accumulation in the "anephric" patient. Cardiovascular effects were seen only with the bolus doses of laudanosine 2 mg kg-1, and at plasma laudanosine concentrations unlikely to be achieved clinically. Similarly, EEG and power spectra analysis showed no evidence of epilept...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/58.suppl_1.14s

    authors: Ingram MD,Sclabassi RJ,Cook DR,Stiller RL,Bennett MH

    更新日期:1986-01-01 00:00:00

  • Does motor block related to long-acting brachial plexus block cause patient dissatisfaction after minor wrist and hand surgery? A randomized observer-blinded trial.

    abstract:BACKGROUND:Patient dissatisfaction has been previously associated with motor block in shoulder surgery patients receiving brachial plexus block. For elective minor wrist and hand surgery, we tested whether a regional block accelerating the early return of upper extremity motor function would improve patient satisfactio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aes266

    authors: Fredrickson MJ,Wolstencroft PJ,Chinchanwala S,Boland MR

    更新日期:2012-11-01 00:00:00

  • Monitoring in the field.

    abstract::This review looks at the challenges faced when monitoring patients in the field environment. It is considered from the perspective of the UK Defence Medical Services and their experiences over the past 20 yr. The lessons learned are applicable to many other circumstances where a high standard of care, for a large spec...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/ael136

    authors: McGuire NM

    更新日期:2006-07-01 00:00:00

  • Intra-abdominal pressure measurement: validation of intragastric pressure as a measure of intra-abdominal pressure.

    abstract:BACKGROUND:The diagnosis of abdominal compartment syndrome depends upon the demonstration of an elevated intra-abdominal pressure (IAP). Direct measures of IAP are impractical in the critical care unit; intravesical pressure (IVP) and intragastric pressure (IGP) should represent acceptable surrogate measures. IVP is th...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aem060

    authors: Turnbull D,Webber S,Hamnegard CH,Mills GH

    更新日期:2007-05-01 00:00:00

  • Arginine-vasopressin attenuates beneficial norepinephrine effect on jejunal mucosal tissue oxygenation during endotoxinaemia.

    abstract:BACKGROUND:The objective of the present study was to investigate the effects of increasing doses of norepinephrine (NE) with or without arginine-vasopressin (AVP) on intestinal oxygen supply and jejunal mucosal tissue oxygen tension in an acute endotoxic pig model. METHODS:In this prospective, randomized, experimental...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aep239

    authors: Maier S,Hasibeder W,Pajk W,Hengl C,Ulmer H,Hausdorfer H,Wurzinger B,Knotzer H

    更新日期:2009-11-01 00:00:00

  • Measurement of lung volume by multiple indicator dilution. Differences in apparent volumes of distribution of oxygen, nitrogen and argon.

    abstract::A variant of a rebreathing/indicator-dilution technique was used to measure lung volume. Two or three indicators, which should have essentially the same pulmonary volume of distribution, were used. Gas compositions were measured by respiratory mass spectrometry and an extrapolation was used to allow for oxygen consump...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/56.3.289

    authors: Black AM,Hahn CE,Maynard P,Scott IL

    更新日期:1984-03-01 00:00:00

  • Effects of inhalation anaesthetics on the release of acetylcholine in the rat cerebral cortex in vivo.

    abstract::By analysing the EEG, reticular multi-unit activity and behavioural changes, we have classified general anaesthetics into three groups: central nervous system (CNS) depressant, CNS excitant and epileptogenic agents. Changes in CNS neural activity are associated with alteration in transmitter release. We have attempted...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/80.3.365

    authors: Shichino T,Murakawa M,Adachi T,Arai T,Miyazaki Y,Mori K

    更新日期:1998-03-01 00:00:00

  • Lower oesophageal contractility and detection of awareness during anaesthesia.

    abstract::We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant c...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/65.3.319

    authors: Isaac PA,Rosen M

    更新日期:1990-09-01 00:00:00

  • Pharmacokinetics of atracurium besylate in healthy patients (after a single i.v. bolus dose).

    abstract::The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/55.2.113

    authors: Ward S,Neill EA,Weatherley BC,Corall IM

    更新日期:1983-02-01 00:00:00

  • Quantitative EEG in assessment of anaesthetic depth: comparative study of methodology.

    abstract::Methodology for assessment of depth of anaesthesia based on analysis of the electroencephalogram (EEG) is controversial. Techniques range from display of single measures, for example median value of the frequency spectrum, to dedicated pattern recognition systems based on measures of several EEG features. We have comp...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/77.2.172

    authors: Thomsen CE,Prior PF

    更新日期:1996-08-01 00:00:00

  • Acoustic monitoring of intraoperative neuromuscular block.

    abstract::Standard methods for accurate intraoperative measurement of neuromuscular block are either expensive or inconvenient and are not used widely. We have evaluated a new method of monitoring neuromuscular block using a low-frequency microphone. The method is based on the phenomenon of low-frequency sound emission by contr...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/83.3.405

    authors: Dascalu A,Geller E,Moalem Y,Manoah M,Enav S,Rudick Z

    更新日期:1999-09-01 00:00:00

  • Possible effects of anaesthetic management on the 1 yr followed-up risk of herpes zoster after Caesarean deliveries.

    abstract:BACKGROUND:As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster am...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer386

    authors: Chen YH,Rau RH,Keller JJ,Lin HC

    更新日期:2012-02-01 00:00:00

  • Evaluation of postural stability after low-dose droperidol in outpatients undergoing gynaecological dilatation and curettage procedure.

    abstract:BACKGROUND:Low-dose droperidol is suggested to be cost-effective in preventing nausea and vomiting after ambulatory surgery. This clinical study evaluated patient postural stability using a computerized force platform after an i.v. dose of droperidol 0.625 mg in outpatients undergoing gynaecological dilatation and cure...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/88.6.819

    authors: Song D,Chung F,Yogendran S,Wong J

    更新日期:2002-06-01 00:00:00

  • Effect of pre- vs postoperative inguinal field block on postoperative pain after herniorrhaphy.

    abstract::The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/68.4.344

    authors: Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

    更新日期:1992-04-01 00:00:00

  • Priming of pancuronium with magnesium.

    abstract::Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/66.2.247

    authors: James MF,Schenk PA,van der Veen BW

    更新日期:1991-02-01 00:00:00

  • Nitrous oxide or halothane, or both, fail to suppress c-fos expression in rat spinal cord dorsal horn neurones after subcutaneous formalin.

    abstract::In rats injected s.c. with formalin, behavioural correlates of the amount and pattern of Fos-like immunoreactivity (Fos-Ll) (molecular responses to pain) were studied to test if early phase treatment with 75% nitrous oxide or 2% halothane, or both, suppressed subsequent spinal sensitization. Rats were allocated to fou...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/76.1.99

    authors: Sun WZ,Shyu BC,Shieh JY

    更新日期:1996-01-01 00:00:00

  • Effects of minor surgery and endotracheal intubation on postoperative breathing patterns in patients anaesthetized with isoflurane or sevoflurane.

    abstract::We studied the effects of minor surgery and endotracheal intubation on postoperative breathing patterns. We measured breathing patterns and laryngeal resistance during the periods immediately before intubation (preoperative) and immediately after extubation following minor surgery (postoperative) in eight patients ana...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/87.5.706

    authors: Tanaka A,Isono S,Sato J,Nishino T

    更新日期:2001-11-01 00:00:00

  • Modification of the iso-shunt lines for low inspired oxygen concentrations.

    abstract::Arterial PO2 (PaO2) has been related to inspired oxygen concentration (FIO2 range 0.21-0.60) in 20 patients, breathing spontaneously, while recovering from a range of conditions treated in an intensive therapy unit. There was a highly significant linear trend (P < 0.001) for the mean venous admixture ("virtual shunt")...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/72.5.515

    authors: Petros AJ,Doré CJ,Nunn JF

    更新日期:1994-05-01 00:00:00

  • Distinct molecular sites of anaesthetic action: pentobarbital block of human brain sodium channels is alleviated by removal of fast inactivation.

    abstract::Fast inactivation of sodium channel function is modified by anaesthetics. Its quantitative contribution to the overall anaesthetic effect is assessed by removing the fast inactivation mechanism enzymatically. Sodium channels from human brain cortex were incorporated into planar lipid bilayers. After incorporation, cha...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/82.1.74

    authors: Wartenberg HC,Urban BW,Duch DS

    更新日期:1999-01-01 00:00:00

  • Comparison of high- and low-dose intrathecal morphine for spinal fusion in children.

    abstract:BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aen025

    authors: Eschertzhuber S,Hohlrieder M,Keller C,Oswald E,Kuehbacher G,Innerhofer P

    更新日期:2008-04-01 00:00:00

  • An assessment of the Gapmeter Lab Kit.

    abstract::The Gapmeter Lab Kit series of flowmeters has been calibrated using air. Two of the flowmeters were also calibrated using argon and oxygen as the priming gases. Linear calibration graphs have been obtained for all the Gapmeters. The two low flow Gapmeters are extremely susceptible to back-pressure. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/49.3.277

    authors: Barnes P,Birdi H

    更新日期:1977-03-01 00:00:00

  • High plasma ropivacaine concentrations after fascia iliaca compartment block in children.

    abstract:BACKGROUND:The pharmacokinetic profile of local anaesthetics is influenced by the mode of administration. We sought to compare the pharmacokinetics of two doses of ropivacaine after fascia iliaca compartment (FIC) block in children. METHODS:In this prospective, double-blind study, children received an FIC block as a p...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/aeh066

    authors: Paut O,Schreiber E,Lacroix F,Meyrieux V,Simon N,Lavrut T,Camboulives J,Bruguerolle B

    更新日期:2004-03-01 00:00:00