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Cloning and sequencing of human LH/hCG receptor cDNA.

Abstract：

:We have isolated and sequenced a cDNA encoding the human luteinizing hormone--choriogonadotropin (LH/hCG) receptor. The deduced amino acid sequence (699 residues) containing seven putative transmembrane segments displays sequence similarity to G protein-coupled receptors. The receptor consists of 335 residue extracellular domain which contains six N-linked glycosylation sites. While the protein is 85 and 87% identical overall with the previously cloned rat and porcine LH/hCG receptor respectively, the most highly conserved regions are the putative transmembrane segments (91 and 94% similarity, respectively).

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Minegishi T,Nakamura K,Takakura Y,Miyamoto K,Hasegawa Y,Ibuki Y,Igarashi M,Minegish T corrected to Minegishi T

doi

10.1016/0006-291x(90)91552-4

subject

Has Abstract

pub_date

1990-11-15 00:00:00

pages

1049-54

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)91552-4

journal_volume

172

pub_type

杂志文章

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