The carbohydrate structures of Trypanosoma brucei brucei MITat 1.6 variant surface glycoprotein. A re-investigation of the C-terminal glycan.

abstract：:Transforming growth factor-beta (TGF-beta) is an inhibitor of the proliferation of bovine aortic endothelial cells in culture. Basal cell growth in serum-containing medium and cell proliferation stimulated by fibroblast growth factor (FGF) are inhibited by TGF-beta in a dose-dependent manner. Half-maximal inhibition o...

journal_title：Biochemical and biophysical research communications

authors： Fràter-Schröder M,Müller G,Birchmeier W,Böhlen P

更新日期：1986-05-29 00:00:00

abstract：:Serotype conversion (O-antigen glucosylation) in Shigella flexneri is mediated by temperate bacteriophages, which encode a three-gene cluster that contains gtrA, gtrB, and gtr([type]). Sequence analysis has revealed that gtrA and gtrB are conserved and readily interchangeable between serotypes. The gtr([type]) is uniq...

journal_title：Biochemical and biophysical research communications

authors： Korres H,Mavris M,Morona R,Manning PA,Verma NK

更新日期：2005-03-25 00:00:00

abstract：:Reversible phosphorylation of RNA polymerase (RNAP) II's largest subunit C-terminal domain (CTD) is a key event during mRNA metabolism. The CTD phosphatase, FCP1, catalyzes the dephosphorylation of RNAP II and is thought to play a major role in polymerase recycling. In this study, we isolated a novel phosphatase gene ...

journal_title：Biochemical and biophysical research communications

authors： Zheng H,Ji C,Gu S,Shi B,Wang J,Xie Y,Mao Y

更新日期：2005-06-17 00:00:00

abstract：:A simple and high yield purification procedure for the isolation of F0F1-ATPase from spinach leaf mitochondria has been developed. This is the first report concerning purification and composition of the plant mitochondrial F0F1-ATPase. The enzyme is selectively extracted from inner membrane vesicles with the zwitterio...

journal_title：Biochemical and biophysical research communications

authors： Hamasur B,Glaser E

更新日期：1990-08-16 00:00:00

abstract：:The genome of Saccharomyces cerevisia encodes four mismatch repair MutL proteins and these proteins form three heterocomplexes: Mlh1-Mlh2, Mlh1-Mlh3, and Mlh1-Pms1. Only, the Mlh1-Mlh3 heterocomplex has been implicated specifically in promotion of meiotic crossing-over. In this report, we show that yeast Mlh3 co-immun...

journal_title：Biochemical and biophysical research communications

authors： Wang TF,Kung WM

更新日期：2002-08-30 00:00:00

abstract：:The recent release of COVID-19 spike glycoprotein allows detailed analysis of the structural features that are required for stabilizing the infective form of its quaternary assembly. Trying to disassemble the trimeric structure of COVID-19 spike glycoprotein, we analyzed single protomer surfaces searching for concave ...

journal_title：Biochemical and biophysical research communications

authors： Bongini P,Trezza A,Bianchini M,Spiga O,Niccolai N

更新日期：2020-07-12 00:00:00

abstract：:Induction of glycogenolysis in the perfused liver by platelet activating factor (PAF) was blocked by the cyclooxygenase inhibitor indomethacin. 3H-labeled PAF was shown to interact in the perfused liver primarily with Kupffer cells. The addition of PAF to Kupffer cells resulted in a dose-dependent stimulation of prost...

journal_title：Biochemical and biophysical research communications

authors： Kuiper J,De Rijke YB,Zijlstra FJ,Van Waas MP,Van Berkel TJ

更新日期：1988-12-30 00:00:00

abstract：:We designed a screen to identify starfish oocyte proteins able to bind monomeric cyclin B by affinity chromatography on a cyclin B splice variant displaying low affinity for cdc2. We identified a 15kDa protein previously described as a cdk-binding protein [Biochim. Biophys. Acta Mol. Cell Res. 1589 (2002) 219-231]. Cy...

journal_title：Biochemical and biophysical research communications

authors： Offner N,Derancourt J,Lozano JC,Schatt P,Picard A,Peaucellier G

更新日期：2003-01-03 00:00:00

abstract：:Microglia, brain macrophages, are thought to be the primary target of HIV-1 infection in the brain, because they exclusively express the CD4 antigen which is effectively used for viral entry. The expression of CD4 mRNA in cultured microglia could be detected by the reverse-PCR method. Using this and immunohistochemica...

journal_title：Biochemical and biophysical research communications

authors： Sawada M,Suzumura A,Marunouchi T

更新日期：1992-12-15 00:00:00

abstract：:Photoreceptor-specific gene expression is controlled by a hierarchical network of transcription factors, including the master regulators cone-rod homeobox (Crx) and neural retina leucine zipper (Nrl). Myocyte-enhancer factor 2c (Mef2c) is an ubiquitously expressed transcription factor with important functions in the c...

journal_title：Biochemical and biophysical research communications

authors： Wolf A,Aslanidis A,Langmann T

更新日期：2017-01-29 00:00:00

abstract：:Upregulation of insulin-like growth factor (IGF)-II expression has been reported for a variety of childhood and adulthood tumors. We determined IGF-II gene promoter usage in human cancerous and benign tissues by semiquantitative RT-PCR using P1-P4-specific primers. Although the human IGF-II gene structure is commonly ...

journal_title：Biochemical and biophysical research communications

authors： Mineo R,Fichera E,Liang SJ,Fujita-Yamaguchi Y

更新日期：2000-02-24 00:00:00

abstract：:Lysophosphatidic acid (LPA) receptors belong to G protein-coupled transmembrane receptors (LPA receptors; LPA(1) to LPA(6)). They indicate a variety of cellular response by the interaction with LPA, including cell proliferation, migration and differentiation. Recently, we have reported that constitutive active mutated...

journal_title：Biochemical and biophysical research communications

authors： Kitayoshi M,Kato K,Tanabe E,Yoshikawa K,Fukui R,Fukushima N,Tsujiuchi T

更新日期：2012-06-01 00:00:00

abstract：:The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome coronavirus (SARS-CoV) plays key roles in viral replication and is an attractive target for anti-SARS drug discovery. In this report, a fluorescence resonance energy transfer (FRET)-based method was developed to assess the proteolytic activity of SAR...

journal_title：Biochemical and biophysical research communications

authors： Kuang WF,Chow LP,Wu MH,Hwang LH

更新日期：2005-06-17 00:00:00

abstract：:Tumor invasion of host tissues and trophoblastic penetration of the endometrium share common biological features. Both processes involve the invasion of basement membranes, an event that is initiated by adhesion of cancer or trophoblast cells to basement membrane components and particularly to laminin. Adhesion to thi...

journal_title：Biochemical and biophysical research communications

authors： van den Brûle FA,Price J,Sobel ME,Lambotte R,Castronovo V

更新日期：1994-05-30 00:00:00

abstract：:The upstream activating region that controls cellulose-induced expression of the glucose-repressible cellobiohydrolase I gene (UARcb1) of the filamentous fungus Trichoderma reesei is shown to mediate transcription and glucose repression of a reporter gene in Saccharomyces cerevisiae, a unicellular microorganism that l...

journal_title：Biochemical and biophysical research communications

authors： Carraro DM,Ferreira Júnior JR,Schumacher R,Pereira GG,Hollenberg CP,El-Dorry H

更新日期：1998-12-18 00:00:00

abstract：:The concept of a glycolytic cancer cell was introduced by Warburg over 70 years ago. This perception has since become the rationale that drives a considerable proportion of basic research on cancer, and it influences the current strategies for the diagnosis, monitoring, and treatment of cancer. Here we review the data...

journal_title：Biochemical and biophysical research communications

authors： Zu XL,Guppy M

更新日期：2004-01-16 00:00:00

abstract：:Structure-function relationships in the 6 epidermal growth factor-like domains of human thrombomodulin (TME, residues 227-462) were studied by deletion mutagenesis. Purified and characterised proteins were used for kinetic studies. Deletion of EGF1, EGF2 and residues 310-332 in EGF3 had no effect on thrombin binding (...

journal_title：Biochemical and biophysical research communications

authors： Parkinson JF,Nagashima M,Kuhn I,Leonard J,Morser J

更新日期：1992-06-15 00:00:00

abstract：:Exosomal microRNAs(miRNAs) transfer from tumor to stromal cells is reportedly associated with cancer progression and metastasis in various epithelial cancers. However, the role of exosomal miRNA in the metastasis of osteosarcoma(OS) -the most common bone malignancy-still largely remains unknown. In this study, we puri...

journal_title：Biochemical and biophysical research communications

authors： Gong L,Bao Q,Hu C,Wang J,Zhou Q,Wei L,Tong L,Zhang W,Shen Y

更新日期：2018-06-02 00:00:00

abstract：:This study was designed to investigate the protective effect of the autophagy signaling pathway against Mycobacterium tuberculosis infection in type II alveolar epithelial cells. An in vitro M. tuberculosis system was established using human A549 cells. Infection-induced changes in the expression of the autophagic mar...

journal_title：Biochemical and biophysical research communications

authors： Guo XG,Ji TX,Xia Y,Ma YY

更新日期：2013-03-08 00:00:00

abstract：:Intestinal epithelial cells (IECs) must be tolerant of the large number of commensal bacteria inhabiting the intestinal tract to avoid excessive inflammatory reactions. Toll-interacting protein (Tollip), a negative regulator of Toll-like receptor signaling, is known to be expressed at high levels in IECs, and to there...

journal_title：Biochemical and biophysical research communications

authors： Sugi Y,Takahashi K,Nakano K,Hosono A,Kaminogawa S

更新日期：2011-09-09 00:00:00

abstract：:Neu2 mRNA from the mouse thymus, as we have reported [K. Kotani, A. Kuroiwa, T. Saito, Y. Matsuda, T. Koda, S. Kijimoto-Ochiai, Cloning, chromosomal mapping, and characteristic 5'-UTR sequence of murine cytosolic sialidase, Biochem. Biophys. Res. Commun. 286 (2001) 250-258], has a novel sequence at the 5' terminus tha...

journal_title：Biochemical and biophysical research communications

authors： Koda T,Kijimoto-Ochiai S,Uemura S,Inokuchi J

更新日期：2009-10-02 00:00:00

abstract：:We found by computer analysis that a putative yeast proteasome subunit gene named PRS3 that encodes a protein very similar to subunit C5 of rat and human proteasomes is located immediately 3' to the ERD2 gene of Saccharomyces cerevisiae. The similarity of the primary structures of the two suggests that this subunit ma...

journal_title：Biochemical and biophysical research communications

authors： Lee DH,Tanaka K,Tamura T,Chung CH,Ichihara A

更新日期：1992-01-31 00:00:00

abstract：:The coffee-specific diterpenes cafestol and kahweol (C+K) have been identified as two important chemoprotective agents in coffee. In the present study, the potential preventive effects of C+K against the genotoxicity of B[a]P were investigated in rat primary hepatocytes and in human bronchial Beas-2B cells. Several in...

journal_title：Biochemical and biophysical research communications

authors： Cavin C,Bezencon C,Guignard G,Schilter B

更新日期：2003-06-27 00:00:00

abstract：:Xenopus XmN-cadherin gene appears to have dual functions, since its mRNA is maternally provided in unfertilized eggs, once disappears almost completely during gastrula stage, then accumulates again specifically in neural tissues in later stage embryos. In the present experiment, we first followed the change in XmN-cad...

journal_title：Biochemical and biophysical research communications

authors： Hojyo T,Tooi O,Tashiro K,Shiokawa K

更新日期：1998-01-06 00:00:00

abstract：:To better understand the mechanism of interactions between G-protein-coupled melatonin receptors and their ligands, our previously reported homology model of human MT2 receptor with docked 2-iodomelatonin was further refined and used to select residues within TM3, TM6, and TM7 potentially important for receptor-ligand...

journal_title：Biochemical and biophysical research communications

authors： Mazna P,Berka K,Jelinkova I,Balik A,Svoboda P,Obsilova V,Obsil T,Teisinger J

更新日期：2005-07-08 00:00:00

abstract：:Two different types of fumarase were found in sonic extracts of Escherichia coli; one required Fe-S for the enzyme activity, and the other did not. When the cells were grown without aeration, the Fe-S-independent enzyme occupied over 80% of the overall fumarase activity. Highly purified Fe-S-independent enzyme was sug...

journal_title：Biochemical and biophysical research communications

authors： Yumoto N,Tokushige M

更新日期：1988-06-30 00:00:00

abstract：:We have investigated the effect of PARP gene inactivation on the expression of wild-type (wt) p53 protein. Using immortalized fibroblasts from control and PARP knock-out mice we have found by immunoblotting with the PAb421 antibody a profound decrease of the p53 expression to a barely detectable level in PARP knock-ou...

journal_title：Biochemical and biophysical research communications

authors： Schmid G,Wang ZQ,Wesierska-Gadek J

更新日期：1999-02-16 00:00:00

abstract：:We describe a novel technology for detecting nucleic acids: Probe Alteration Link Self-Assembly Reactions (PALSAR). PALSAR comprises DNA self-assembly of pairs of short DNA probes formed by alternate hybridization of three complementary regions in a pair of honeycomb probes (HCPs). Self-assembly occurs at designated s...

journal_title：Biochemical and biophysical research communications

authors： Usui M,Fujikawa T,Osawa M,Hakii C,Ikumi N,Nozaki T,Kitamura N,Hatta Y,Fujiwara S,Takei M

更新日期：2015-11-27 00:00:00

abstract：:Plant innate immunity varies with age and plant developmental stages. Recently, we reported that Arabidopsis thaliana microRNA miR172b regulates FLS2 transcription through two transcription factors: TARGET OF EAT1 (TOE1) and TOE2. Although the flg22-triggered immune responses were investigated in 2-d-old or even young...

journal_title：Biochemical and biophysical research communications

authors： Zou Y,Wang S,Lu D

更新日期：2020-10-22 00:00:00

abstract：:To examine the possibility that the Orf135 protein of Escherichia coli functions as a hydrolyzing enzyme for a damaged DNA precursor (deoxyribonucleoside 5'-triphosphate), we purified the recombinant Orf135 protein and incubated it with oxidized deoxynucleotides. Of the nucleotides tested, 2-hydroxydeoxyadenosine 5'-t...

journal_title：Biochemical and biophysical research communications

authors： Kamiya H,Murata-Kamiya N,Iida E,Harashima H

更新日期：2001-11-02 00:00:00