Abstract:
:The anti-herpes simplex virus type 1 and anti-herpes simplex virus type 2 effects of apple pomace, a by-product from the cider-processing industry, were investigated. The mechanisms of antiviral action were assessed using a battery of experiments targeting sequential steps in the viral replication cycle. The anti-herpetic mechanisms of apple pomaces included the inhibition of virus attachment to the cell surface and the arrest of virus entry and uncoating. Quercitrin and procyanidin B2 were found to play a crucial role in the antiviral activity.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Alvarez AL,Melón S,Dalton KP,Nicieza I,Roque A,Suárez B,Parra Fdoi
10.1089/jmf.2011.0308subject
Has Abstractpub_date
2012-06-01 00:00:00pages
581-7issue
6eissn
1096-620Xissn
1557-7600journal_volume
15pub_type
杂志文章abstract::High-performance liquid chromatography (HPLC) or capillary electrophoresis (CE) is particularly suited to the separation and analysis of a wide range of biological compounds. When investigating such compounds in complex matrices (e.g., blood, tissue, urine, foods), specificity of the detection method becomes an import...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.1999.2.111
更新日期:1999-01-01 00:00:00
abstract::Candidiasis is the most frequent infection by opportunistic fungi, frequently caused by Candida albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata, and Candida krusei. Mentha arvensis L. is a herbaceous plant that occurs throughout South America and is used as a tea and in the folk medicine. Turnera ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.0128
更新日期:2012-03-01 00:00:00
abstract::Broccoli belongs to a group of cruciferous vegetables characterized by its content of glucosinolates, secondary metabolites that, upon hydrolysis, release bioactive isothiocyanates (ITCs). Sulforaphane, the major ITC from broccoli, is believed to protect the body from cancer by induction of detoxification enzymes such...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/109662004322984770
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abstract::In South America, particularly in the Northeastern regions of Brazil, Turnera subulata leaf extract is used as an alternative traditional medicine approach for several types of chronic diseases, such as diabetes, hypertension, chronic pain, and general inflammation. Despite its widespread use, little is known about th...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2016.0047
更新日期:2016-10-01 00:00:00
abstract::To evaluate the effect of berberine (BBR) plus bezafibrate administration on the lipid profile of patients with mixed dyslipidemia. A double-blind randomized pilot clinical trial with parallel groups was carried out in 36 patients, aged 30-60 years with mixed dyslipidemia [triglycerides (TG) ≥1.7 mM and total choleste...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2020.0029
更新日期:2020-05-12 00:00:00
abstract::The present study evaluated the protective effect of Centella asiatica (gotu kola) leaf extract (CAE) against indomethacin (IND)-induced gastric mucosal injury in rats. Gastric mucosal injury was induced by the oral administration of IND to the rats after a 24 h fast. CAE (50 or 250 mg/kg) or lansoprazole (a reference...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2015.3464
更新日期:2016-01-01 00:00:00
abstract::Long-term therapy with doxorubicin (DOX) is associated with high incidence of cumulative and irreversible dilated cardiomyopathy. The goal of this study was to evaluate the cardioprotective effects and safety of a phlorotannin extract from a brown algae Ecklonia cava (Seapolynol™, SPN) against DOX-induced cardiotoxici...
journal_title:Journal of medicinal food
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doi:10.1089/jmf.2017.3919
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abstract::Premature ejaculation (PE) is one of the foremost sex-related health problems among men. The global occurrence ranges from 20% to 30%, according to various studies. PE has a great impact on the men's quality of life, with deleterious effects such as embarrassment, frustration, and feeling of incompetence. Considering ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.4661
更新日期:2020-09-01 00:00:00
abstract::High glucose levels can change podocyte gene expression and subsequently induce podocyte damage through altered glucose metabolism. l-Carnitine is known to play a beneficial role in diabetes; however, there are no studies on the effects of l-carnitine on podocyte alteration under high glucose conditions. This study in...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.1079
更新日期:2010-12-01 00:00:00
abstract::We investigated the effect of solid-state fermented rice cultured with Basidiomycota (sangwhang) and Monascus ruber on lipid metabolism and antioxidant activity. Forty 4-week-old male Sprague-Dawley rats were fed high cholesterol diets in which carbohydrate sources in the treatment groups consisted of non-fermented ri...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.227
更新日期:2007-12-01 00:00:00
abstract::An antioxidant substance (AOS) obtained from an enzymatic extract of the red seaweed Gloiopeltis tenax was purified by DEAE-Sephadex CL-6B and Sephadex G-100 column chromatography. The purification yield of AOS was 14.3%. The AOS predominantly contained fucose, mannose, and galactose but also contained a sulfate group...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2007.0688
更新日期:2009-04-01 00:00:00
abstract::Different polysaccharides were isolated from the leaves of Aloe arborescens using the gradient power of hydrogen followed by antitumor and immunomodulatory assay. The total polysaccharide content of different fractions, water-soluble polysaccharide (WAP), acid-soluble polysaccharide (ACP), and alkaline-soluble polysac...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2016.0148
更新日期:2017-05-01 00:00:00
abstract::Impaired fasting blood glucose is one of the landmark signs of metabolic syndrome, together with hyperinsulinemia, dyslipidemia, hypertension, and a chronic proinflammatory, pro-oxidative, and prothrombotic environment. This study investigates the effect of wild blueberry (WB) consumption on blood glucose levels and o...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2014.0065
更新日期:2015-06-01 00:00:00
abstract::Prostatism and erectile dysfunction (ED) are highly prevalent and closely comorbid. Prescription treatments are limitingly expensive but robust in mechanisms of action (MoA). Nutritional supplements (NS) are low-cost but inadequately supported by evidence. Do any NS use robust MoA? Could their efficacy be amplified vi...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2018.0148
更新日期:2019-05-01 00:00:00
abstract::Antimicrobial activities of 10-100% (wt/vol) concentrations of new honey, stored honey, heated honey, ultraviolet-exposed honey, and heated stored honey were tested against common human pathogens, including Escherichia coli, Entrobacter cloacae, Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella sp., Haemophilus...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/1096620041224139
更新日期:2004-07-01 00:00:00
abstract::Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disease resulting in joint destruction and disability in the adult population. The etiology of RA is not well understood and presently there is no known cure for this disease. The accumulation and proliferation of fibroblast-like synoviocytes may be i...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.0046
更新日期:2019-10-01 00:00:00
abstract::The intake of milk has decreased over the past few decades in Western populations and has been replaced by drinks of plant origin. Substitution of cow's milk by vegetable drinks occurs for some reasons, such as the presence of lactose intolerance, reduced calorie intake, prevention of obesity, vegan diets, and concern...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2020.0031
更新日期:2020-06-16 00:00:00
abstract::Probiotic complex, zinc, and coenzyme Q10 (CoQ10) are recognized dietary supplements with an anti-inflammatory role. Although these supplementations are individually known to benefit rheumatoid arthritis (RA), there is no evidence suggesting any synergic effect. The primary goal of this study is to determine whether p...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2017.3952
更新日期:2018-01-01 00:00:00
abstract::The present study investigated the effect of phloretin [2',4',6'-trihydroxy-3-(4-hydroxyphenyl)-propiophenone] on 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression and tumor promotion in mouse skin and explored the underlying molecular mechanisms. Topical application of phloretin s...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.1851
更新日期:2012-03-01 00:00:00
abstract::We investigated the effect of kaikasaponin III (KS-III) on Phase I and II enzymes and tissue factor (TF) activity to elucidate the pharmacological actions of this immunosuppressive saponin in the diabetic rat. This compound was obtained from the flower of Pueraria thunbergiana (Leguminosae) by chromatographic isolatio...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/109662004322984671
更新日期:2004-04-01 00:00:00
abstract::The effects of the turmeric ethyl acetate fraction (TEF) from the methanolic extract from Curcuma longa L. on lipid metabolism and underlying mechanisms of lipolysis were investigated in 3T3-L1 adipocytes. The intracellular lipid droplets were stained with Oil red O dye and quantified. Compared to the control, lipid a...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2009.1276
更新日期:2010-04-01 00:00:00
abstract::Vernonia amygdalina Del. (Family Compositae) is used in Nigerian folk medicine as a tonic and remedy against constipation, fever, high blood pressure, and many infectious diseases. We have evaluated the hepatoprotective and antioxidant effects of an aqueous extract of V. amygdalina leaves against acetaminophen-induced...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.524
更新日期:2006-01-01 00:00:00
abstract::Isoliquiritigenin (ISL), a flavonoid chalcone that is present in licorice, shallot, and bean sprouts, is known to have antitumorigenic activities. The present study examined whether ISL alters prostate cancer cell cycle progression. DU145 human and MatLyLu (MLL) rat prostate cancer cells were cultured with various con...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0039
更新日期:2009-02-01 00:00:00
abstract::The oxygen radical absorbance capacity (ORAC) assay has been widely used to quantify peroxyl radical scavenging capacity of pure antioxidant compounds and antioxidant plant/food extracts. However, it has never been applied to natural compounds derived from microalgae-based dietary supplements, namely, phycocyanin (PC)...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0257
更新日期:2010-02-01 00:00:00
abstract::Overwhelming evidence indicates that consumption of fruits and vegetables with antioxidant properties correlates with reduced risk for cancers, including leukemia. Carrots contain beneficial agents, such as β-carotene and polyacetylenes, which could be effective in the treatment of leukemia. This study investigated th...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.0284
更新日期:2011-11-01 00:00:00
abstract::Cytokine-induced cell death is recognized as a major cause of progressive β-cell loss. Tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and interferon γ (IFN-γ) in combination trigger a series of events that lead to β-cell death. In the past few decades, the use of myricetin as an anti-inflammatory and cytopro...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.2033
更新日期:2012-08-01 00:00:00
abstract::Insufficient sleep, insomnia, and sleep-related problems are important health issues, as their overall prevalence accounts for about 30% of the general population. The aim of this study was to systematically review previous studies investigating the effects of orally administered single plant-derived extracts on sleep...
journal_title:Journal of medicinal food
pub_type: 杂志文章,评审
doi:10.1089/jmf.2017.4064
更新日期:2018-05-01 00:00:00
abstract::Obesity is characterized by an increase in the infiltration of monocytes into the adipose tissue, causing an inflammatory condition associated with, for example, the development of insulin resistance. Thus, anti-inflammatory-based treatments could emerge as a novel and interesting approach. It has been reported that C...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2014.0031
更新日期:2015-05-01 00:00:00
abstract::The antioxidant effect of the ethanolic root extract of Hemidesmus indicus, an indigenous Ayurvedic medicinal plant used in soft drinks in India, was studied in rats with ethanol-induced hepatotoxicity. Administering 20% ethanol (5 g/kg of body weight/day) for 60 days to male Wistar rats resulted in significantly decr...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.110
更新日期:2007-12-01 00:00:00
abstract::Ilex latifolia Thunb. (Aquifoliaceae), a Chinese bitter tea called "kudingcha," has been widely consumed as a health beverage and found to possess antioxidant, antidiabetic, antihypertensive, anti-inflammatory, and anti-ischemic activities. The aim of the present study was to investigate the neuroprotective effects of...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2015.3443
更新日期:2015-12-01 00:00:00