A Randomized Double-Blind Placebo-Control Study to Assess the Efficacy and Safety of OLNP-05 Versus Placebo for the Treatment of Subjects with Premature Ejaculation.

abstract：:Panax ginseng (P. ginseng C.A. Meyer, Araliaceae) is used as a therapeutic agent for various diseases. P. ginseng saponins, known as ginsenosides, are the main bioactive compounds responsible for its pharmacological activities. In this work, we have developed a new method of P. ginseng root processing termed solid-sta...

journal_title：Journal of medicinal food

authors： Park CH,Kim M,Woo M,Lee KH,An BK,Yokozawa T,Song YO

更新日期：2018-04-01 00:00:00

abstract：:One of the critical features of Alzheimer's disease is cognitive dysfunction, which is, in part, due to decreases in acetylcholine (ACh). The ethanol extract of Perilla frutescens was selected for isolating the acetylcholinesterase (AChE) inhibitor based on preliminary screening. In vivo behavioral tests were performe...

journal_title：Journal of medicinal food

authors： Choi SJ,Oh SS,Kim CR,Kwon YK,Suh SH,Kim JK,Park GG,Son SY,Shin DH

更新日期：2016-03-01 00:00:00

abstract：:3,3'-diindolylmethane is a major in vivo metabolite of indole-3-carbinol, a bioactive compound found in cruciferous vegetables. Although 3,3'-diindolylmethane has been implicated to possess antitumorigenic and anti-inflammatory properties, the effect of 3,3'-diindolylmethane on adipogenesis has not been explored previ...

journal_title：Journal of medicinal food

authors： Lee J,Yue Y,Park Y,Lee SH

更新日期：2017-07-01 00:00:00

abstract：:This study investigated the effects and possible mechanism of ferulic acid, a naturally occurring phenolic compound, on endogenous glutamate release in the nerve terminals of the cerebral cortex in rats. Results show that ferulic acid inhibited the release of glutamate evoked by the K⁺ channel blocker 4-aminopyridine ...

journal_title：Journal of medicinal food

authors： Lin TY,Lu CW,Huang SK,Wang SJ

更新日期：2013-02-01 00:00:00

abstract：UNLABELLED:Opuntia ficus-indica (OFI) is a cactus species widely used as an anti-inflammatory, antilipidemic, and hypoglycemic agent. It has been shown that OFI extract (OFIE) inhibits oxidative stress in animal models of diabetes and hepatic disease; however, its antioxidant mechanism remains largely unknown. In this ...

journal_title：Journal of medicinal food

authors： Nakahara T,Mitoma C,Hashimoto-Hachiya A,Takahara M,Tsuji G,Uchi H,Yan X,Hachisuka J,Chiba T,Esaki H,Kido-Nakahara M,Furue M

更新日期：2015-10-01 00:00:00

abstract：:Propolis was included in the Argentine Food Code as a functional food. The chemical parameters and antioxidant properties of propolis samples from the same colonies of Apis mellifera in San Juan (Cuyo region, Western Argentine) were compared every month for 1 year using two collection methods. Chemical parameters were...

journal_title：Journal of medicinal food

authors： Isla MI,Zampini IC,Ordóñez RM,Cuello S,Juárez BC,Sayago JE,Moreno MI,Alberto MR,Vera NR,Bedascarrasbure E,Alvarez A,Cioccini F,Maldonado LM

更新日期：2009-12-01 00:00:00

abstract：:Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a counterintuitive positive correlation between MSTN and muscle mass (MM). Our aim was to investigate the influence of 2 months of resistance training (RT) and diets with different protein contents on plasma MSTN, interleukin 1 b...

journal_title：Journal of medicinal food

authors： Paoli A,Pacelli QF,Neri M,Toniolo L,Cancellara P,Canato M,Moro T,Quadrelli M,Morra A,Faggian D,Plebani M,Bianco A,Reggiani C

更新日期：2015-01-01 00:00:00

abstract：:The prevalence of obesity is expanding rapidly worldwide, making the disease a global burden with limited treatment options. The current obesity drug development trends suggest the possibility of reducing weight and reverse metabolic disturbances of obesity by controlling appetite. In this study, we screened more than...

journal_title：Journal of medicinal food

authors： Yimam M,Jiao P,Hong M,Brownell L,Lee YC,Kim HJ,Nam JB,Kim MR,Jia Q

更新日期：2019-07-01 00:00:00

abstract：:Candidiasis is the most frequent infection by opportunistic fungi, frequently caused by Candida albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata, and Candida krusei. Mentha arvensis L. is a herbaceous plant that occurs throughout South America and is used as a tea and in the folk medicine. Turnera ...

journal_title：Journal of medicinal food

authors： Santos KK,Matias EF,Souza CE,Tintino SR,Braga MF,Guedes GM,Nogueira LF,Morais EC,Costa JG,Menezes IR,Coutinho HD

更新日期：2012-03-01 00:00:00

abstract：:In this study, the effects of Humulus japonicus (HJ) aqueous extract on 3T3-L1 preadipocytes and HepG2 cells (in vitro model) as well as on C57BL/6 mice fed on high-fat diet (HFD) (in vivo model) were evaluated. Mice fed on HFD for 12-weeks were taken the HJ water extract (HJW) at various doses, 50, 150, and 250 mg/kg...

journal_title：Journal of medicinal food

authors： Chung YH,Bang JS,Kang CM,Goh JW,Lee HS,Hong SM,Kim DS,Park ES,Jung TW,Shin YK,Lee JH,Jeong JH

更新日期：2018-10-01 00:00:00

abstract：:Phenethyl isothiocyanate (PITC) is the hydrolysis product of the glucosinolate gluconasturtiin in cruciferous vegetables. This study was conducted to determine whether PITC inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in the mouse ear. Topical application of 5 nmol of TPA to mouse ears mark...

journal_title：Journal of medicinal food

authors： Lee YM,Cho HJ,Ponnuraj SP,Kim J,Kim JS,Kim SG,Park JH

更新日期：2011-04-01 00:00:00

abstract：:The medical ethnobotanical knowledge propagated over generations in the coastal regions of the Eastern Mediterranean, including Lebanon, is one that has built on several ancient cultures and civilizations of these regions. Recent interest in medical ethnobotany and the use of medicinal herbs in treating or preventing ...

journal_title：Journal of medicinal food

authors： Talhouk RS,Karam C,Fostok S,El-Jouni W,Barbour EK

更新日期：2007-03-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of salidroside on lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E₂ (PGE₂) production in RAW 264.7 macrophages and related anti-inflammatory mechanism. PGE₂ production was measured by enzyme-linked immunosorbent assay (ELISA); NO production was tes...

journal_title：Journal of medicinal food

authors： Song B,Huang G,Xiong Y,Liu J,Xu L,Wang Z,Li G,Lu J,Guan S

更新日期：2013-11-01 00:00:00

abstract：:Bilberry (European blueberry) has been reported to have many biological effects, including anticancer activity. In this study, we investigated the antiproliferative effects of bilberry extract in relation to its ability to induce apoptosis and affect microtubule assembly and organization in MCF7 human breast cancer ce...

journal_title：Journal of medicinal food

authors： Nguyen V,Tang J,Oroudjev E,Lee CJ,Marasigan C,Wilson L,Ayoub G

更新日期：2010-04-01 00:00:00

abstract：:The oral cytotoxicity, antimicrobial and anti-demineralizing effects of a tincture from Bauhinia forficata Link tincture (BFLT) were evaluated in vitro and ex vivo. Susceptibility tests (minimum inhibitory and microbicidal concentrations-MIC and time-kill assay-MMC) were performed against planktonic oral microorganism...

journal_title：Journal of medicinal food

authors： Ferreira-Filho JCC,Marre ATO,de Sá Almeida JS,Lobo LA,Farah A,Romanos MTV,Maia LC,Valença AMG,Fonseca-Gonçalves A

更新日期：2020-09-01 00:00:00

abstract：:Different polysaccharides were isolated from the leaves of Aloe arborescens using the gradient power of hydrogen followed by antitumor and immunomodulatory assay. The total polysaccharide content of different fractions, water-soluble polysaccharide (WAP), acid-soluble polysaccharide (ACP), and alkaline-soluble polysac...

journal_title：Journal of medicinal food

authors： Nazeam JA,Gad HA,Esmat A,El-Hefnawy HM,Singab AB

更新日期：2017-05-01 00:00:00

abstract：:This study sought to characterize the effects of some citrus fruit juices (shaddock [Citrus maxima], grapefruit [Citrus paradisii], lemon [Citrus limoni], orange [Citrus sinensis], and tangerine [Citrus reticulata]) on acetylcholinesterase activity in vitro. The total phenolic content, radical scavenging abilities, an...

journal_title：Journal of medicinal food

authors： Ademosun AO,Oboh G

更新日期：2012-05-01 00:00:00

abstract：:To investigate the effectiveness of nutritional supplement Bao Khi Khang as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease (COPD) compared to conventional therapy alone. This was a prospective, randomized, open-label controlled trial in 60 patients presenting with acute exacerbatio...

journal_title：Journal of medicinal food

authors： Hoang BX,Han B,Nguyen HX,Dang KT

更新日期：2018-10-01 00:00:00

abstract：:The effects of the turmeric ethyl acetate fraction (TEF) from the methanolic extract from Curcuma longa L. on lipid metabolism and underlying mechanisms of lipolysis were investigated in 3T3-L1 adipocytes. The intracellular lipid droplets were stained with Oil red O dye and quantified. Compared to the control, lipid a...

journal_title：Journal of medicinal food

authors： Lee J,Yoon HG,Lee YH,Park J,You Y,Kim K,Jang JY,Yang JW,Jun W

更新日期：2010-04-01 00:00:00

abstract：:Species of Hoodia Sweet ex Decne., family Apocynaceae, a southern African succulent plant, have been recognized for their appetite suppressing properties. Products that support appetite and weight control have been developed in Israel from locally cultivated Hoodia spp. To study consumer acceptance, efficacy of, and t...

journal_title：Journal of medicinal food

authors： Landor M,Benami A,Segev N,Loberant B

更新日期：2015-02-01 00:00:00

abstract：:The anti-ulcer potentials of aqueous (AE) and methanol (ME) extracts of whole unripe Carica papaya fruit were evaluated using ethanol- and indomethacin-induced gastric ulcer models in rats. The effect of the extracts on small intestinal propulsion was also investigated. The extracts significantly reduced the ulcer ind...

journal_title：Journal of medicinal food

authors： Ezike AC,Akah PA,Okoli CO,Ezeuchenne NA,Ezeugwu S

更新日期：2009-12-01 00:00:00

abstract：:The major limitation of Doxorubicin (Dox) clinical use is the development of chronic and acute toxic side effects induced through the generation of reactive oxygen species. The present work was designated to investigate in vitro effects of a red grape-seed hydroethanolic extract Burgund Mare (BM), in associated admini...

journal_title：Journal of medicinal food

authors： Postescu ID,Chereches G,Tatomir C,Daicoviciu D,Filip GA

更新日期：2012-07-01 00:00:00

abstract：:Obesity is generally associated with low-grade chronic inflammation that involves the recruitment of macrophages and other inflammation factors to the adipocytes of obese individuals. Tumor necrosis factor-alpha (TNF-α), a cytokine associated with systemic inflammation, is elevated in conditions of obesity. TNF-α is a...

journal_title：Journal of medicinal food

authors： Marthandam Asokan S,Hung TH,Chiang WD,Lin WT

更新日期：2018-03-01 00:00:00

abstract：:The transport behavior and absorption mechanism of Ala-His-Leu-Leu (AHLL) intestinal absorption in Caco-2 cell monolayers were clarified systemically. The safe absorptive concentration of AHLL was 200 μg/mL, which was determined by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. The permeat...

journal_title：Journal of medicinal food

authors： Li Y,Zhao J,Liu X,Xia X,Wang Y,Zhou J

更新日期：2017-03-01 00:00:00

abstract：:High-performance liquid chromatography (HPLC) or capillary electrophoresis (CE) is particularly suited to the separation and analysis of a wide range of biological compounds. When investigating such compounds in complex matrices (e.g., blood, tissue, urine, foods), specificity of the detection method becomes an import...

journal_title：Journal of medicinal food

authors： Barnes S,Wang CC,Smith-Johnson M,Kirk M

更新日期：1999-01-01 00:00:00

abstract：:Standardized extracts of Echinacea, cat's claw, and saw palmetto were each evaluated for ability to activate macrophage and natural killer cells, in vitro, using two independent measures of activation for each immune cell population. A standard series of exposure concentrations were tested for each herbal extract in a...

journal_title：Journal of medicinal food

authors： Groom SN,Johns T,Oldfield PR

更新日期：2007-03-01 00:00:00

abstract：:Garlic protects against degenerative diseases such as hyperlipidemia and cardiovascular diseases. However, raw garlic has a strong pungency, which is unpleasant. In this study, we examined the effect of high temperature/high pressure-processed garlic on plasma lipid profiles in rats. Sprague-Dawley rats were fed a nor...

journal_title：Journal of medicinal food

authors： Sohn CW,Kim H,You BR,Kim MJ,Kim HJ,Lee JY,Sok DE,Kim JH,Lee KJ,Kim MR

更新日期：2012-05-01 00:00:00

abstract：:This 12-week, double-blind, placebo-controlled study investigated the effects of fertilized egg powder (Young Tissue Extract; YT®) intake on outcome measures for depression. Fifty-five patients with depression were randomly assigned to receive YTE, YTE plus Melissa officinalis, or placebo for 12 weeks. At baseline, th...

journal_title：Journal of medicinal food

authors： Solberg E

更新日期：2011-07-01 00:00:00

abstract：:Abnormal expression of pro-inflammatory mediators such as cell adhesion molecules and cytokines has been implicated in various inflammatory skin diseases, including atopic dermatitis. In this study, we investigated the anti-inflammatory activity of Aronia melanocarpa concentrate (AC) and its action mechanisms using in...

journal_title：Journal of medicinal food

authors： Goh AR,Youn GS,Yoo KY,Won MH,Han SZ,Lim SS,Lee KW,Choi SY,Park J

更新日期：2016-07-01 00:00:00

abstract：:Fifty-four potential probiotic candidates were assayed for their phenotypic susceptibility to two batches of antibiotics manufactured by the same company, using the agar disc diffusion method on de Man, Rogosa, and Sharpe (MRS) agar. Cloxacillin was generally resisted (40.0-100%), while gentamicin (3.85-20.0%) was the...

journal_title：Journal of medicinal food

authors： Ogunshe AA

更新日期：2008-12-01 00:00:00