Abstract:
:The oxygen radical absorbance capacity (ORAC) assay has been widely used to quantify peroxyl radical scavenging capacity of pure antioxidant compounds and antioxidant plant/food extracts. However, it has never been applied to natural compounds derived from microalgae-based dietary supplements, namely, phycocyanin (PC) and phycocyanobilin (PCB), for which a strong radical scavenger activity has been documented. In this article, we applied the ORAC method to investigate the capacity of PC and PCB purified from the edible microalga Aphanizomenon flos-aquae to directly quench peroxyl radicals in comparison to well-known antioxidants molecules such as Trolox, ascorbic acid, and reduced glutathione. As a result, PCB was found to have the highest ORAC value (22.18 micromol of Trolox/micromol of compound), comparable to that of PC (20.33 micromol of Trolox/micromol of compound), hence confirming that PCB is mostly responsible for the scavenger activity of PC and making the protein a possible source of the antioxidant in vivo. Our data further corroborate the use of these natural compounds from A. flos-aquae as dietary antioxidant supplements in the treatment of clinical conditions related to oxidative stress.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Benedetti S,Benvenuti F,Scoglio S,Canestrari Fdoi
10.1089/jmf.2008.0257subject
Has Abstractpub_date
2010-02-01 00:00:00pages
223-7issue
1eissn
1096-620Xissn
1557-7600journal_volume
13pub_type
杂志文章abstract::Propolis was included in the Argentine Food Code as a functional food. The chemical parameters and antioxidant properties of propolis samples from the same colonies of Apis mellifera in San Juan (Cuyo region, Western Argentine) were compared every month for 1 year using two collection methods. Chemical parameters were...
journal_title:Journal of medicinal food
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journal_title:Journal of medicinal food
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pub_type: 杂志文章
doi:10.1089/jmf.2008.1260
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doi:10.1089/jmf.2012.0184
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更新日期:2010-06-01 00:00:00
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pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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